Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Rosanna C T Wright"'
Autor:
Jessica E Buddle, Lucy M Thompson, Anne S Williams, Rosanna C T Wright, William M Durham, Claire E Turner, Roy R Chaudhuri, Michael A Brockhurst, Robert P Fagan
Publikováno v:
PLoS Biology, Vol 22, Iss 8, p e3002741 (2024)
Clostridioides difficile is an important human pathogen, for which there are very limited treatment options, primarily the glycopeptide antibiotic vancomycin. In recent years, vancomycin resistance has emerged as a serious problem in several gram-pos
Externí odkaz:
https://doaj.org/article/53a85d31ba3c433588634f1cb67da377
Autor:
James P J Hall, Rosanna C T Wright, Ellie Harrison, Katie J Muddiman, A Jamie Wood, Steve Paterson, Michael A Brockhurst
Publikováno v:
PLoS Biology, Vol 19, Iss 10, p e3001225 (2021)
Plasmids play an important role in bacterial genome evolution by transferring genes between lineages. Fitness costs associated with plasmid carriage are expected to be a barrier to gene exchange, but the causes of plasmid fitness costs are poorly und
Externí odkaz:
https://doaj.org/article/e7b6d25f6bc941739af7e8d0c266d785
Publikováno v:
PLoS Biology, Vol 16, Iss 10, p e2006057 (2018)
Phages shape the structure of natural bacterial communities and can be effective therapeutic agents. Bacterial resistance to phage infection, however, limits the usefulness of phage therapies and could destabilise community structures, especially if
Externí odkaz:
https://doaj.org/article/eea8df8076dc4f3496f2bc186799cf56
Autor:
Eleri A. Ashworth, Rosanna C. T. Wright, Rebecca K. Shears, Janet K. L. Wong, Akram Hassan, James P. J. Hall, Aras Kadioglu, Joanne L. Fothergill
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Pseudomonas aeruginosa is a major nosocomial pathogen that causes severe disease including sepsis. Carbapenem-resistant P. aeruginosa is recognised by the World Health Organisation as a priority 1 pathogen, with urgent need for new therapeut
Externí odkaz:
https://doaj.org/article/d7674a4d2b9846549863382aa65c4b86
Autor:
Rebecca C. Hull, Rosanna C. T. Wright, Jon R. Sayers, Joshua A. F. Sutton, Julia Rzaska, Simon J. Foster, Michael A. Brockhurst, Alison M. Condliffe
Publikováno v:
Antimicrobial Agents and Chemotherapy. 66
Bacterial pathogens are confronted with a range of challenges at the site of infection, including exposure to antibiotic treatment and harsh physiological conditions, that can alter the fitness benefits and costs of acquiring antibiotic resistance. H
Publikováno v:
Nature ecologyevolution. 6(12)
Publikováno v:
Wright, R C T, Friman, V, Smith, M C M & Brockhurst, M A 2021, ' Functional diversity increases the efficacy of phage combinations ', Microbiology, vol. 167, no. 12 . https://doi.org/10.1099/mic.0.001110
Microbiology
Microbiology
Phage therapy is a promising alternative to traditional antibiotics for treating bacterial infections. Such phage-based therapeutics typically contain multiple phages, but how the efficacy of phage combinations scales with phage richness, identity an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58003a4af52ffc1de7069578773eb3aa
https://doi.org/10.1101/2021.07.09.451746
https://doi.org/10.1101/2021.07.09.451746
Autor:
Rosanna C. T. Wright, Jean-Paul Pirnay, Gilbert Verbeken, Els Van Mechelen, Daniel De Vos, Stefan Vermeulen, Ville-Petri Friman, Mario Vaneechoutte, Hans Duyvejonck, Maya Merabishvili, Steven de Soir
Publikováno v:
Viruses
VIRUSES-BASEL
Viruses, Vol 13, Iss 865, p 865 (2021)
Volume 13
Issue 5
VIRUSES-BASEL
Viruses, Vol 13, Iss 865, p 865 (2021)
Volume 13
Issue 5
In Belgium, the incorporation of phages into magistral preparations for human application has been permitted since 2018. The stability of such preparations is of high importance to guarantee quality and efficacy throughout treatments. We evaluated th
Autor:
Rosanna C. T. Wright, Katie J. Muddiman, Jamie Wood, Steve Paterson, James P. J. Hall, Ellie Harrison, Michael A. Brockhurst
Plasmids play an important role in bacterial genome evolution by transferring genes between lineages. Fitness costs associated with plasmid acquisition are expected to be a barrier to gene exchange, but the causes of plasmid fitness costs are poorly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2beb0c77e14bd93c795431a44751db22
http://livrepository.liverpool.ac.uk/3140393/1/journal.pbio.3001225.pdf
http://livrepository.liverpool.ac.uk/3140393/1/journal.pbio.3001225.pdf
Publikováno v:
Ferris, C, Wright, R, Brockhurst, M A & Best, A 2020, ' The evolution of host resistance and parasite infectivity is highest in seasonal resource environments that oscillate at intermediate amplitudes ', Proceedings. Biological sciences, vol. 287, no. 1927 . https://doi.org/10.1098/rspb.2020.0787
Proc Biol Sci
Proc Biol Sci
Seasonal environments vary in their amplitude of oscillation but the effects of this temporal heterogeneity for host–parasite coevolution are poorly understood. Here, we combined mathematical modelling and experimental evolution of a coevolving bac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e83eea97f065f740067979fa0d4a99f4
https://www.research.manchester.ac.uk/portal/en/publications/the-evolution-of-host-resistance-and-parasite-infectivity-is-highest-in-seasonal-resource-environments-that-oscillate-at-intermediate-amplitudes(d79dc3f3-c0d3-4e7f-9110-c7fc6ad9440e).html
https://www.research.manchester.ac.uk/portal/en/publications/the-evolution-of-host-resistance-and-parasite-infectivity-is-highest-in-seasonal-resource-environments-that-oscillate-at-intermediate-amplitudes(d79dc3f3-c0d3-4e7f-9110-c7fc6ad9440e).html