Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Rosana Gonzalez-Quintial"'
Autor:
Juan Yu, Elsa Meneses-Salas, Jennifer L. Johnson, Susanna Manenti, Mouad Ait Kbaich, Danni Chen, Kasra Askari, Jing He, Aparna Shukla, Binchu Shaji, Rosana Gonzalez-Quintial, Ben A. Croker, Jinzhong Zhang, Hal Hoffman, William B. Kiosses, Catherine Hedrick, Kersi Pestonjamasp, Nathan Wineinger, Roberto Baccala, Sergio D. Catz
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114598- (2024)
Summary: Endosomal Toll-like receptors (eTLRs) are essential for the sensing of non-self through RNA and DNA detection. Here, using spatiotemporal analysis of vesicular dynamics, super-resolution microscopy studies, and functional assays, we show tha
Externí odkaz:
https://doaj.org/article/45ad18936d5d4d02bc4122545d0ebb95
Autor:
Travis S Young, Argyrios N Theofilopoulos, Hua Huang, Sophie Viaud, Dwight H Kono, Ivo Rimann, Parker Mace, Rosana Gonzalez-Quintial, Eduardo Laborda, Hannah Mora
Publikováno v:
Lupus Science and Medicine, Vol 9, Iss Suppl 3 (2022)
Externí odkaz:
https://doaj.org/article/3a60732fcea74c6eacd12ca649110527
Autor:
Rosana Gonzalez-Quintial, Anthony Nguyen, Dwight H Kono, Michael B A Oldstone, Argyrios N Theofilopoulos, Roberto Baccala
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0203118 (2018)
Viruses have long been implicated in the pathogenesis of autoimmunity, yet their contribution remains circumstantial partly due to the lack of well-documented information on infections prior to autoimmune disease onset. Here, we used the lymphocytic
Externí odkaz:
https://doaj.org/article/b5446786087442ccab9764e2f21a58b1
Autor:
Rosana Gonzalez-Quintial, Brian R Lawson, John C Scatizzi, Joseph Craft, Dwight H Kono, Roberto Baccala, Argyrios N Theofilopoulos
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27528 (2011)
Lupus is characterized by disturbances in lymphocyte homeostasis, as demonstrated by the marked accumulation of activated/memory T cells. Here, we provide evidence that proliferation of the CD8+ precursors for the accumulating CD4⁻CD8⁻ T cells in
Externí odkaz:
https://doaj.org/article/b9d7bec00d634e8283fc46b4c6097ea2
Autor:
Michael J Barnes, Philippe Krebs, Nathaniel Harris, Celine Eidenschenk, Rosana Gonzalez-Quintial, Carrie N Arnold, Karine Crozat, Sosathya Sovath, Eva Marie Moresco, Argyrios N Theofilopoulos, Bruce Beutler, Kasper Hoebe
Publikováno v:
PLoS Biology, Vol 7, Iss 3, p e51 (2009)
Regulatory T (T(reg)) cells expressing forkhead box P3 (Foxp3) arise during thymic selection among thymocytes with modestly self-reactive T cell receptors. In vitro studies suggest Foxp3 can also be induced among peripheral CD4(+) T cells in a cytoki
Externí odkaz:
https://doaj.org/article/81de9018dcbd4a3388ceff1a8b7757de
Autor:
Ivo Rimann, Hua Huang, Parker Mace, Rosana Gonzalez-Quintial, Eduardo Laborda, Sophie Viaud, Hannah Mora, Argyrios N Theofilopoulos, Travis S Young, Dwight H Kono
Publikováno v:
Lupus 21st Century 2022 Abstract.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cc5b1f4d5b22522a1f0b5cdf60444a8
https://doi.org/10.1136/lupus-2022-lupus21century.87
https://doi.org/10.1136/lupus-2022-lupus21century.87
Autor:
Ivo Rimann, Rosana Gonzalez-Quintial, Roberto Baccala, William B. Kiosses, John R. Teijaro, Christopher G. Parker, Xiaohong Li, Bruce Beutler, Dwight H. Kono, Argyrios N. Theofilopoulos
Publikováno v:
Proceedings of the National Academy of Sciences. 119
A function-impairing mutation (feeble) or genomic deletion of SLC15A4 abolishes responses of nucleic acid–sensing endosomal toll-like receptors (TLRs) and significantly reduces disease in mouse models of lupus. Here, we demonstrate disease reductio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a688a515daff2177953b9730f9c51c79
https://doi.org/10.1073/pnas.2200544119
https://doi.org/10.1073/pnas.2200544119
Autor:
Jessica M. Mayeux, Rosana Gonzalez-Quintial, Kenneth Michael Pollard, Roberto Baccala, Argyrios N. Theofilopoulos, Dwight H. Kono
Publikováno v:
Clin Immunol
Considerable evidence indicates that autoimmune disease expression depends on both genetic and environmental factors. Among potential environmental triggers, occupational airway exposure to crystalline silica and virus infections have been linked to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4705d480c4610c981ae0668d8292b41
https://doi.org/10.1016/j.clim.2019.06.003
https://doi.org/10.1016/j.clim.2019.06.003
Autor:
Theodoros Eleftheriadis, Michael A. Farrar, Dwight H. Kono, Argyrios N. Theofilopoulos, Dorian B. McGavern, Karsten Sauer, Rosana Gonzalez-Quintial, Brian R. Lawson, Stephen D. Miller, Roberto Baccala
Publikováno v:
Clinical Immunology. 161:260-269
IL-7 is known to be vital for T cell homeostasis but has previously been presumed to be dispensable for TCR-induced activation. Here, we show that IL-7 is critical for the initial activation of CD4(+) T cells in that it provides some of the necessary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::826cec7bff93d6a3976eaf3ea6bf74c0
https://doi.org/10.1016/j.clim.2015.08.007
https://doi.org/10.1016/j.clim.2015.08.007
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1604
Hemorrhagic fever (HF) viruses, such as Lassa, Ebola, and dengue viruses, represent major human health risks due to their highly contagious nature, the severity of the clinical manifestations induced, the lack of vaccines, and the very limited therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e8a85578abe157c027a9f44e4b05d14c
https://pubmed.ncbi.nlm.nih.gov/28986841
https://pubmed.ncbi.nlm.nih.gov/28986841