Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Rosana F, Marta"'
Autor:
Geraldine De Luca, Nora P. Goette, Paola R. Lev, Maria C. Baroni Pietto, Cecilia P. Marin Oyarzún, Miguel A. Castro Ríos, Beatriz Moiraghi, Federico Sackmann, Laureano J. Kamiya, Veronica Verri, Victoria Caula, Vanina Fernandez, Angeles Vicente, Julio Pose Cabarcos, Vanesa Caruso, Maria F. Camacho, Irene B. Larripa, Marina Khoury, Rosana F. Marta, Ana C. Glembotsky, Paula G. Heller
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Inflammation plays a pivotal role in the pathogenesis of primary and post-essential thrombocythemia or post-polycythemia vera myelofibrosis (MF) in close cooperation with the underlying molecular drivers. This inflammatory state is induced by a dynam
Externí odkaz:
https://doaj.org/article/5df717c398dd4954b8dd7bab8a1b84c2
Autor:
Geraldine De Luca, Paola R. Lev, Maria F. Camacho, Nora P. Goette, Federico Sackmann, Miguel A. Castro Ríos, Beatriz Moiraghi, Veronica Cortes Guerrieri, Georgina Bendek, Emiliano Carricondo, Alicia Enrico, Veronica Vallejo, Ana Varela, Marina Khoury, Marina Gutierrez, Irene B. Larripa, Rosana F. Marta, Ana C. Glembotsky, Paula G. Heller
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Myelofibrosis (MF) is a clonal hematopoietic stem cell disorder classified among chronic myeloproliferative neoplasms, characterized by exacerbated myeloid and megakaryocytic proliferation and bone marrow fibrosis. It is induced by driver (JAK2/CALR/
Externí odkaz:
https://doaj.org/article/5d6f229ff02c42ab976c494419308bc5
Pathogenic mechanisms contributing to thrombocytopenia in patients with systemic lupus erythematosus
Autor:
M. Constanza Baroni Pietto, Paola R. Lev, Ana C. Glembotsky, Cecilia P. Marín Oyarzún, Graciela Gomez, Victoria Collado, Cecilia Pisoni, Ramiro A. Gomez, Matías Grodzielski, Jacqueline Gonzalez, Karina V. Mariño, Paula G. Heller, Nora P. Goette, Rosana F. Marta
Publikováno v:
Platelets, Vol 33, Iss 5, Pp 743-754 (2022)
Systemic lupus erythematosus (SLE) is an autoimmune condition developing thrombocytopenia in about 10–15% of cases, however, mechanisms leading to low platelet count were not deeply investigated in this illness. Here we studied possible causes of t
Externí odkaz:
https://doaj.org/article/6b513b6ff98045f69f1dba0a75e76380
Autor:
Ana C. Glembotsky, Cecilia P. Marin Oyarzún, Geraldine De Luca, Christophe Marzac, Nathalie Auger, Nora P. Goette, Rosana F. Marta, Hana Raslova, Paula G. Heller
Publikováno v:
Haematologica, Vol 105, Iss 10 (2020)
Externí odkaz:
https://doaj.org/article/a61daa6f8d7444bebdd2a4aca751d131
Autor:
Cecilia P. Marín Oyarzún, Ana C. Glembotsky, Nora P. Goette, Paola R. Lev, Geraldine De Luca, María C. Baroni Pietto, Beatriz Moiraghi, Miguel A. Castro Ríos, Angeles Vicente, Rosana F. Marta, Mirta Schattner, Paula G. Heller
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Essential thrombocythemia (ET) is comprised among chronic myeloproliferative neoplasms (MPN) and is caused by driver mutations in JAK2, CALR, and MPL, which lead to megakaryocyte proliferation and prominent thrombocytosis. Thrombosis remains the main
Externí odkaz:
https://doaj.org/article/c645814c0eff4aa58503e674a2eb6b47
Autor:
Juan P. Salim, Ana C. Glembotsky, Paola R. Lev, Cecilia P. Marin Oyarzún, Nora P. Goette, Felisa C. Molinas, Rosana F. Marta, Paula G. Heller
Publikováno v:
Platelets, Vol 28, Iss 6, Pp 602-606 (2017)
The SDF-1-CXCR4 axis plays an essential role in the regulation of platelet production, by directing megakaryocyte (MK) migration toward the vascular niche, thus allowing terminal maturation and proplatelet formation, and also regulates platelet funct
Externí odkaz:
https://doaj.org/article/9930007e5cf5435d86432ae6f12f066b
Autor:
Ana C. Glembotsky, Dominika Sliwa, Dominique Bluteau, Nathalie Balayn, Cecilia P. Marin Oyarzún, Anna Raimbault, Marie Bordas, Nathalie Droin, Iryna Pirozhkova, Valance Washington, Nora P. Goette, Rosana F. Marta, Rémi Favier, Hana Raslova, Paula G. Heller
Publikováno v:
Haematologica, Vol 104, Iss 6 (2019)
Germline RUNX1 mutations lead to thrombocytopenia and platelet dysfunction in familial platelet disorder with predisposition to acute myelogenous leukemia (AML). Multiple aspects of platelet function are impaired in these patients, associated with al
Externí odkaz:
https://doaj.org/article/339e7f5175834da7a016b084f1a82957
Pathogenic mechanisms contributing to thrombocytopenia in patients with systemic lupus erythematosus
Autor:
Cecilia Paola Marin Oyarzún, Jacqueline Gonzalez, Graciela Gómez, Karina Mariño, M. Constanza Baroni Pietto, Paula G. Heller, Victoria Collado, Paola Roxana Lev, Ana C. Glembotsky, Ramiro Gomez, Cecilia Pisoni, Matías Grodzielski, Nora Paula Goette, Rosana F. Marta
Publikováno v:
Platelets. 33:743-754
SummarySystemic lupus erythematosus (SLE) is an autoimmune condition developing thrombocytopenia in about 10-15% of cases, however, mechanisms leading to low platelet count were not deeply investigated in this illness. Here we studied possible causes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e63f822cffa59c40c8819d31f528368
https://doi.org/10.1080/09537104.2021.1988547
https://doi.org/10.1080/09537104.2021.1988547
Autor:
Nora P Goette, Ana C Glembotsky, Paola R Lev, Matías Grodzielski, Geraldine Contrufo, Marta S Pierdominici, Yesica R Espasandin, Dardo Riveros, Alejandro J García, Felisa C Molinas, Paula G Heller, Rosana F Marta
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160563 (2016)
Mechanisms leading to decreased platelet count in immune thrombocytopenia (ITP) are heterogeneous. This study describes increased platelet apoptosis involving loss of mitochondrial membrane potential (ΔΨm), caspase 3 activation (aCasp3) and phospha
Externí odkaz:
https://doaj.org/article/bc764d30bd6a4f0e9a65c2e73f793414
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Primary immune thrombocytopenia (ITP) is an autoimmune disorder characterized by the decrease in peripheral blood platelet count below 100 x 109/L, and an increased bleeding risk when thrombocytopenia drops below 30 x 109/L. The mechanisms leading to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f93a036cca90310053d102add3be28
https://doi.org/10.29245/2578-3009/2020/2.1185
https://doi.org/10.29245/2578-3009/2020/2.1185