Knockdown of the Plasmodium falciparum SURFIN4.1 antigen leads to an increase of its cognate transcript.

Autor: Tatiane Macedo-Silva, Rosana Beatriz Duque Araujo, Kamila Anna Meissner, Wesley Luzetti Fotoran, Márcia Melo Medeiros, Mauro Ferreira de Azevedo, Gerhard Wunderlich

Publikováno v: PLoS ONE, Vol 12, Iss 8, p e0183129 (2017)

The genome of the malaria parasite Plasmodium falciparum contains the surf gene family which encodes large transmembrane proteins of unknown function. While some surf alleles appear to be expressed in sexual stages, others occur in asexual blood stag

Externí odkaz: https://doaj.org/article/d022b7df4155499b907c2817c6f31f58

Inflammasome activation and IL-1 signaling during placental malaria induce poor pregnancy outcomes

Autor: Erika Paula Machado Peixoto, Vinícius Nunes Cordeiro Leal, Rosana Beatriz Duque Araujo, Carla Letícia Bandeira, Gerhard Wunderlich, Carlos Penha-Gonçalves, Rita Neres, Jamille Gregório Dombrowski, Claudio Romero Farias Marinho, Franciele Araujo, Vinícius M. Gomes, Aramys Silva Reis, Flávia Afonso Lima, André Barateiro, Sabrina Epiphanio, Fabio T. M. Costa, Giuseppe Palmisano, Lígia Antunes Gonçalves, Rodrigo Medeiros de Souza, Alessandra Pontillo, Karina R. Bortoluci, Leticia Labriola, Carsten Wrenger, Estela Bevilacqua, Oscar Murillo, Renato Barboza

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Science Advances

IL-1 axis activation during placental malaria induces poor pregnancy outcomes that are obliterated after treatment with Anakinra.
Placental malaria (PM) is associated with severe inflammation leading to abortion, preterm delivery, and intrauteri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2987d6f314e50d16284f588529bb8343
https://doi.org/10.1126/sciadv.aax6346

Independent regulation of Plasmodium falciparum rif gene promoters

Autor: Diego Peres Alonso, Charlotte Sophie Kaiser, Tatiane Macedo Silva, Gabriela Fernandes Leite, Paulo Eduardo Martins Ribolla, Rosana Beatriz Duque Araujo, Gerhard Wunderlich

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Scientific Reports
Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)

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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab8da35319a75d4d74f5d76841f6dd40