Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Rosamund F. Langston"'
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
IntroductionEpisodic memory formation requires the binding of multiple associations to a coherent episodic representation, with rich detail of times, places, and contextual information. During postnatal development, the ability to recall episodic mem
Externí odkaz:
https://doaj.org/article/4059500523e34f54b6f6577d9b77ca0e
Autor:
Fiona H. McLean, Fiona M. Campbell, Domenico Sergi, Christine Grant, Amanda C. Morris, Elizabeth A. Hay, Alasdair MacKenzie, Claus D. Mayer, Rosamund F. Langston, Lynda M. Williams
Publikováno v:
Nutrition & Metabolism, Vol 16, Iss 1, Pp 1-12 (2019)
Abstract Background The rise in global obesity makes it crucial to understand how diet drives obesity-related health conditions, such as premature cognitive decline and Alzheimer’s disease (AD). In AD hippocampal-dependent episodic memory is one of
Externí odkaz:
https://doaj.org/article/1e42aeb5fb4b482ea5b66f3a2bbbb077
Autor:
Fiona H. McLean, Fiona M. Campbell, Rosamund F. Langston, Domenico Sergi, Cibell Resch, Christine Grant, Amanda C. Morris, Claus D. Mayer, Lynda M. Williams
Publikováno v:
Nutrition & Metabolism, Vol 16, Iss 1, Pp 1-16 (2019)
Abstract Background Prolonged over-consumption of a high-fat diet (HFD) commonly leads to obesity and insulin resistance. However, even 3 days of HFD consumption has been linked to inflammation within the key homeostatic brain region, the hypothalamu
Externí odkaz:
https://doaj.org/article/2318658f9a1a48a3b56ea4f02d5bb0ee
Autor:
Malcolm R. Macleod, Lynda M. Williams, Fiona J Ramage, Alexander S Clewlow, Rosamund F. Langston
Publikováno v:
BMJ Open Science. 44
Introduction and objective The Western diet that comprises high levels of long-chain saturated fats and sugar is associated not only with metabolic disorders such as obesity and type 2 diabetes but also has been recently linked to brain changes and c
Autor:
Lidy van Aalten, Calum Sutherland, Rory J. McCrimmon, Alison D. McNeilly, Nicola Morrice, Ewan R. Pearson, Rosamund F. Langston
Publikováno v:
BMC Research Notes
BMC Research Notes, Vol 13, Iss 1, Pp 1-6 (2020)
BMC Research Notes, Vol 13, Iss 1, Pp 1-6 (2020)
Objectives GLUT2 is a major facilitative glucose transporter, expressed from the SLC2A2 gene, with essential roles in the liver. Recent work in mice has shown that preventing Glut2 production in specific neuronal populations increases sugar-seeking b
Autor:
Rosamund F. Langston, Claus-Dieter Mayer, Christine Grant, Fiona H. McLean, Fiona Margaret Campbell, Cibell Resch, Domenico Sergi, Lynda M. Williams, Amanda C. Morris
Publikováno v:
Nutrition & Metabolism
Nutrition & Metabolism, Vol 16, Iss 1, Pp 1-16 (2019)
Nutrition & Metabolism, Vol 16, Iss 1, Pp 1-16 (2019)
Background Prolonged over-consumption of a high-fat diet (HFD) commonly leads to obesity and insulin resistance. However, even 3 days of HFD consumption has been linked to inflammation within the key homeostatic brain region, the hypothalamus. Method
Publikováno v:
Behavioural brain research, 2018, Vol.354, pp.48-54 [Peer Reviewed Journal]
Previous work has shown that depletion of the cholinergic input to the hippocampus produces no impairment in an episodic (what-where-which) memory task in rats. However, in contrast a where-which task was significantly impaired. Models of acetylcholi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0f841b8b88f5015b7222a78fc26bd8f
http://dro.dur.ac.uk/22242/1/22242.pdf
http://dro.dur.ac.uk/22242/1/22242.pdf
Autor:
Hirofumi Watari, Sybille Krauss, Katharina Meyer, Sven Buettner, Isabelle Arnoux, Axel Methner, Rosamund F. Langston, Nina Offermann, Daniele Bano, Konstantin Radyushkin, Jennifer Krummeich, Partha Narayan Dey, Erich E. Wanker, Jeremy J. Lambert, Stephanie Weber, Susann Schweiger, Olivia Monteiro, Nadine Griesche, Changwei Chen, Albrecht Stroh, Michael Willam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d264c210d5b7c6d3b9fe835ae7698487
https://doi.org/10.7554/elife.38744.032
https://doi.org/10.7554/elife.38744.032
Autor:
Jennifer Krummeich, Jeremy J. Lambert, Axel Methner, Sven Buettner, Isabelle Arnoux, Hirofumi Watari, Nina Offermann, Daniele Bano, Sybille Krauss, Michael Willam, Albrecht Stroh, Konstantin Radyushkin, Erich E. Wanker, Susann Schweiger, Olivia Monteiro, Stephanie Weber, Rosamund F. Langston, Partha Narayan Dey, Nadine Griesche, Changwei Chen, Katharina Meyer
Publikováno v:
eLife 7, e38744 (2018). doi:10.7554/eLife.38744
eLife, Vol 7 (2018)
eLife, Vol 7 (2018)
Catching primal functional changes in early, ‘very far from disease onset’ (VFDO) stages of Huntington’s disease is likely to be the key to a successful therapy. Focusing on VFDO stages, we assessed neuronal microcircuits in premanifest Hdh150
Autor:
Rachel Buxton, Jeremy J. Lambert, Angela Bridges, Rosamund F. Langston, Argyrides Argyrou, Emma J. Jones, Christina Pancevac Jönsson, Susann Schweiger, Olivia Monteiro, Kelly M Gatfield, Changwei Chen, Ryan P. Bingham, Sybille Krauß, Iain Uings
Publikováno v:
Neuroscience letters 673, 44-50 (2018). doi:10.1016/j.neulet.2018.02.061
Expression of mutant Huntingtin (HTT) protein is central to the pathophysiology of Huntington's Disease (HD). The E3 ubiquitin ligase MID1 appears to have a key role in facilitating translation of the mutant HTT mRNA suggesting that interference with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15711b74e62ed0a10bb56478546bb0e5