Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Rosamaria Y. Moreno"'
Autor:
Rosamaria Y. Moreno, Kyle J. Juetten, Svetlana B. Panina, Jamie P. Butalewicz, Brendan M. Floyd, Mukesh Kumar Venkat Ramani, Edward M. Marcotte, Jennifer S. Brodbelt, Y. Jessie Zhang
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107581- (2023)
Summary: During eukaryotic transcription, RNA polymerase II undergoes dynamic post-translational modifications on the C-terminal domain (CTD) of the largest subunit, generating an information-rich PTM landscape that transcriptional regulators bind. T
Externí odkaz:
https://doaj.org/article/508e48fd4c6846dc911d42011f3bddbf
Autor:
Rosamaria Y. Moreno, Y. Jessie Zhang
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7dd61c71e3b32a149c66785cb55f911
https://doi.org/10.1096/fasebj.2022.36.s1.r2019
https://doi.org/10.1096/fasebj.2022.36.s1.r2019
Autor:
Edwin E. Escobar, Jamie P. Butalewicz, Haoyi Wu, Seema Irani, Joshua E. Mayfield, Meena Tadros, Jennifer S. Brodbelt, Yan Jessie Zhang, Mukesh Kumar Venkat Ramani, Victoria C. Cotham, Rosamaria Y. Moreno
Publikováno v:
ACS Chem Biol
The phosphorylation states of RNA polymerase II coordinate the process of eukaryotic transcription by recruitment of transcription regulators. The individual residues of the repetitive heptad of the C-terminal domain (CTD) of the biggest subunit of R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee83e328dbc5ab82b20770d0506fc49
https://europepmc.org/articles/PMC8018230/
https://europepmc.org/articles/PMC8018230/
SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia
Autor:
Sofya A. Polyanskaya, Rosamaria Y. Moreno, Bin Lu, Ruopeng Feng, Yu Yao, Seema Irani, Olaf Klingbeil, Zhaolin Yang, Yiliang Wei, Osama E. Demerdash, Lukas A. Benjamin, Mitchell J. Weiss, Yan Jessie Zhang, Christopher R. Vakoc
Publikováno v:
Cell reports
SUMMARY Acute myeloid leukemia (AML) cells rely on phospho-signaling pathways to gain unlimited proliferation potential. Here, we use domain-focused CRISPR screening and identify the nuclear phosphatase SCP4 as a dependency in AML, yet this enzyme is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c91745687cd5858c5579fe8e011b536
https://doi.org/10.1016/j.celrep.2021.110233
https://doi.org/10.1016/j.celrep.2021.110233