A retrospective study of MYC rearranged diffuse large B-cell lymphoma in the context of the new WHO and ICC classifications

Autor: Dima El-Sharkawi, Amit Sud, Catherine Prodger, Jahanzaib Khwaja, Rohan Shotton, Brian Hanley, Victoria Peacock, Ying Ying Peng, Anita Arasaretnam, Sarkhara Sharma, Frances Aldridge, Bhupinder Sharma, Andrew Wotherspoon, Betty Cheung, Corinne De Lord, Rosalynd Johnston, Shireen Kassam, Ruth Pettengel, Kim Linton, Paul Greaves, Lucy Cook, Kikkeri N. Naresh, Kate Cwynarski, Toby A. Eyre, Ian Chau, David Cunningham, Sunil Iyengar

Publikováno v: Blood Cancer Journal, Vol 13, Iss 1, Pp 1-5 (2023)

Externí odkaz: https://doaj.org/article/f34c82b257694a09bb76d27d1f3ce733

Elucidation of focal adhesion kinase as a modulator of migration and invasion and as a potential therapeutic target in chronic lymphocytic leukemia

Autor: Thomas A. Burley, Andrew Hesketh, Giselda Bucca, Emma Kennedy, Eleni E. Ladikou, Benjamin P. Towler, Simon Mitchell, Colin P. Smith, Christopher Fegan, Rosalynd Johnston, Andrea Pepper, Chris Pepper

Publikováno v: Cancers; Volume 14; Issue 7; Pages: 1600

The retention and re-migration of Chronic Lymphocytic Leukemia cells into cytoprotective and proliferative lymphoid niches is thought to contribute to the development of resistance, leading to subsequent disease relapse. The aim of this study was to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6033be23d4398ad55c99441917225162

Real-world experience of ibrutinib therapy in relapsed chronic lymphocytic leukemia: results of a single-center retrospective analysis

Autor: Elisabeth Nuttall, Timothy Chevassut, Rosalynd Johnston, Ellie Trounce, Joanna Tung

Publikováno v: Journal of Blood Medicine. 10:199-208

Background: Ibrutinib is a Bruton’s tyrosine-kinase (BTK) inhibitor that is approved as a second-line treatment in chronic lymphocytic leukemia (CLL). While recent trials have demonstrated impressive results for ibrutinib, there remains a paucity o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d1b3f8166b2cb90dab913c2ec2326242
https://doi.org/10.2147/jbm.s202286

The effect of initiation of renin-angiotensin system inhibitors on haemoglobin: A national cohort study

Autor: Masao Iwagami, Laurie A. Tomlinson, Dorothea Nitsch, Clemence Leyrat, George Greenhall, Liam Smeeth, Kathryn E. Mansfield, Rosalynd Johnston

Publikováno v: Br J Clin Pharmacol

AIMS: To determine whether initiation of treatment with angiotensin converting enzyme inhibitors or angiotensin II receptor blockers (ACEI/ARBs) is associated with a subsequent reduction in haemoglobin in the general population. METHODS: We undertook

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d794332fefcbe8b3f87eebbd276c13f7
https://researchonline.lshtm.ac.uk/id/eprint/4661628/1/bcp.14429.pdf

Sequence analysis of exon 1 of the ferritin light chain (FTL) gene can reveal the rare disorder ‘hereditary hyperferritinaemia without cataracts’

Autor: Sambit Sen, Charlotte Bradbury, Wale Atoyebi, Helene Dreau, Terence S. Elsey, P Bignell, Meha Bhuva, Rosalynd Johnston, William J.H. Griffiths

Publikováno v: Bradbury, C 2018, ' Sequence analysis of exon 1 of the ferritin light chain (FTL) gene can reveal the rare disorder ‘hereditary hyperferritinaemia without cataracts’ ', British Journal of Haematology . https://doi.org/10.1111/bjh.15231

[no abstract]

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b3971f4e701e48d50fec985631628b
https://hdl.handle.net/1983/c633ad32-eb93-4106-b25c-7bacf8b8a33f