Zobrazeno 1 - 10
of 230
pro vyhledávání: '"Rosalinde Masereeuw"'
Autor:
Zhenguo Wang, Chen Xing, Luc J. W. van der Laan, Monique M. A. Verstegen, Bart Spee, Rosalinde Masereeuw
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Background Drug induced bile duct injury is a frequently observed clinical problem leading to a wide range of pathological features. During the past decades, several agents have been identified with various postulated mechanisms of bile duct
Externí odkaz:
https://doaj.org/article/8d28353034a843c4be8fec25debc89e5
Autor:
João Faria, Sandra Calcat-i-Cervera, Renata Skovronova, Bonnie C. Broeksma, Alinda J. Berends, Esther A. Zaal, Benedetta Bussolati, Timothy O’Brien, Silvia M. Mihăilă, Rosalinde Masereeuw
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Background Ischemia/reperfusion injury is the leading cause of acute kidney injury (AKI). The current standard of care focuses on supporting kidney function, stating the need for more efficient and targeted therapies to enhance repair. Mesen
Externí odkaz:
https://doaj.org/article/757863cdf2334d1997254857f5683e3b
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/ccb7c33416ac48ba96aa50419b881b95
Autor:
Marit Keuper-Navis, Markus Walles, Birk Poller, Adam Myszczyszyn, Thomas K. van der Made, Joanne Donkers, Hossein Eslami Amirabadi, Martijn J. Wilmer, Saskia Aan, Bart Spee, Rosalinde Masereeuw, Evita van de Steeg
Publikováno v:
Pharmacological Research, Vol 195, Iss , Pp 106853- (2023)
Organ-on-chip (OoC) technology has led to in vitro models with many new possibilities compared to conventional in vitro and in vivo models. In this review, the potential of OoC models to improve the prediction of human oral bioavailability and intrin
Externí odkaz:
https://doaj.org/article/06d95e9d904945618f9e6018cbd79e94
Bioengineered intestinal tubules as a tool to test intestinal biological efficacy of lettuce species
Autor:
Paulus G. M. Jochems, Bo Heming, Dmitry Lapin, Naomi E. L. Moonen, Guido Van den Ackerveken, Rosalinde Masereeuw
Publikováno v:
npj Science of Food, Vol 6, Iss 1, Pp 1-8 (2022)
Abstract Lettuce (Lactuca sativa) is one of the most consumed and cultivated vegetables globally. Its breeding is focused on the improvement of yield and disease resistance. However, potential detrimental or beneficial health effects for the consumer
Externí odkaz:
https://doaj.org/article/6608032288874fa1b660eb9fe5c28c50
Autor:
Rafael Soares Lindoso, Fjodor A. Yousef Yengej, Franziska Voellmy, Maarten Altelaar, Estela Mancheño Juncosa, Theano Tsikari, Carola M. E. Ammerlaan, Bas W. M. Van Balkom, Maarten B. Rookmaaker, Marianne C. Verhaar, Rosalinde Masereeuw
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract The prevalence of end-stage kidney disease (ESKD) is rapidly increasing with the need for regenerative therapies. Adult stem cell derived kidney tubuloids have the potential to functionally mimic the adult kidney tubule, but still lack the e
Externí odkaz:
https://doaj.org/article/331cae23c0ff4b0498dd6f9d94d91a78
Publikováno v:
Biomedicines, Vol 11, Iss 9, p 2408 (2023)
Chronic kidney disease (CKD) is a progressive condition of kidney dysfunction due to diverse causes of injury. In healthy kidneys, protein-bound uremic toxins (PBUTs) are cleared from the systemic circulation by proximal tubule cells through the conc
Externí odkaz:
https://doaj.org/article/f2c87ce104a84135821f0c511b5d50ec
Autor:
Sabbir Ahmed, Joost C. de Vries, Jingyi Lu, Milan H. Verrijn Stuart, Silvia M. Mihăilă, Robin W. M. Vernooij, Rosalinde Masereeuw, Karin G. F. Gerritsen
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13197 (2023)
Protein-bound uremic toxins (PBUTs) are associated with the progression of chronic kidney disease (CKD) and its associated morbidity and mortality. The conventional dialysis techniques are unable to efficiently remove PBUTs due to their plasma protei
Externí odkaz:
https://doaj.org/article/f5e232913d884b3fae8ab1d62e2ab698
Autor:
João Faria, Sabbir Ahmed, Dimitrios Stamatialis, Marianne C. Verhaar, Rosalinde Masereeuw, Karin G. F. Gerritsen, Silvia M. Mihăilă
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12435 (2023)
Patients with end-stage kidney disease (ESKD) suffer from high levels of protein-bound uremic toxins (PBUTs) that contribute to various comorbidities. Conventional dialysis methods are ineffective in removing these PBUTs. A potential solution could b
Externí odkaz:
https://doaj.org/article/069ce47ad04b47809b09858af751a200
Autor:
Zhenguo Wang, João Faria, Luc J. W. van der Laan, Louis C. Penning, Rosalinde Masereeuw, Bart Spee
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Liver diseases affect hundreds of millions of people worldwide; most often the hepatocytes or cholangiocytes are damaged. Diseases of the biliary tract cause severe patient burden, and cholangiocytes, the cells lining the biliary tract, are sensitive
Externí odkaz:
https://doaj.org/article/cab7f83ee5244511aa9e4af4fb961bd8