Výsledky vyhledávání - "Rosalind F, Cook"

β 2 ‐Adrenoceptors indirectly support impaired β 1 ‐adrenoceptor responsiveness in the isolated type 2 diabetic rat heart

Autor: Carol T. Bussey, Gillian Hughes, Andrew Bahn, Patricia A. Cragg, Regis R. Lamberts, Ingrid C. Fomison-Nurse, Rosalind F. Cook

Publikováno v: Experimental Physiology. 104:808-818

NEW FINDINGS What is the central question of this study? Are there specific contributions of β1 - and β2 -adrenoceptor subtypes to the impaired β-adrenoceptor responsiveness of the type 2 diabetic heart? What is the main finding and its importance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7ef565c05c3ae6f8e47859b9ce62b985
https://doi.org/10.1113/ep087437

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β1-Adrenoceptor, but not β2-adrenoceptor, subtype regulates heart rate in type 2 diabetic ratsin vivo

Autor: Kimberley M. Mellor, Regis R. Lamberts, Carol T. Bussey, Patricia A. Cragg, Rosalind F. Cook

Publikováno v: Experimental Physiology. 102:911-923

New Findings What is the central question of the study? The sympathetic system regulates heart rate via β-adrenoceptors; this is impaired during diabetes. However, the specific β-adrenoceptor subtype contributions in heart rate regulation in diabet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a38498ea6cc65f3ea57a1f39d6f5959b
https://doi.org/10.1113/ep086293

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Autor: Rosalind F, Cook, Carol T, Bussey, Ingrid C, Fomison-Nurse, Gillian, Hughes, Andrew, Bahn, Patricia A, Cragg, Regis R, Lamberts

Publikováno v: Experimental physiology. 104(6)

What is the central question of this study? Are there specific contributions of βImpaired β-adrenoceptor (β-AR) responsiveness causes cardiac vulnerability in patients with type 2 diabetes, but the independent contributions of β

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c6e116e137f016d074ed45013b174233
https://pubmed.ncbi.nlm.nih.gov/30889297

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Dual implantation of a radio-telemeter and vascular access port allows repeated hemodynamic and pharmacological measures in conscious lean and obese rats

Autor: John C. Schofield, Zoe Ashley, Carol T. Bussey, Regis R. Lamberts, Rosalind F. Cook, A E de Leeuw

Publikováno v: Laboratory Animals. 48:250-260

Expansion of physiological knowledge increasingly requires examination of processes in the normal, conscious state. The current study describes a novel approach combining surgical implantation of radio-telemeters with vascular access ports (VAPs) to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a27c443b89bc252627f7df87208c87eb
https://doi.org/10.1177/0023677214530687

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Autor: Rosalind F, Cook, Carol T, Bussey, Kimberley M, Mellor, Patricia A, Cragg, Regis R, Lamberts

Publikováno v: Experimental physiology. 102(8)

What is the central question of the study? The sympathetic system regulates heart rate via β-adrenoceptors; this is impaired during diabetes. However, the specific β-adrenoceptor subtype contributions in heart rate regulation in diabetes in vivo ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dddee358288af4cede5354cc296243d1
https://pubmed.ncbi.nlm.nih.gov/28543947

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Increased Efferent Cardiac Sympathetic Nerve Activity and Defective Intrinsic Heart Rate Regulation in Type 2 Diabetes

Autor: Andrew Bahn, Peter P. Jones, Regis R. Lamberts, Rosalind F. Cook, Carol T. Bussey, Daryl O. Schwenke, H. P. Aye Thaung, J. Chris Baldi, Phil W Sheard, Heng-Yu Wang, Gillian Hughes

Publikováno v: Diabetes. 64(8)

Elevated sympathetic nerve activity (SNA) coupled with dysregulated β-adrenoceptor (β-AR) signaling is postulated as a major driving force for cardiac dysfunction in patients with type 2 diabetes; however, cardiac SNA has never been assessed direct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7741153ddc71d6a78c60526ab78de8b7
https://pubmed.ncbi.nlm.nih.gov/26207035

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