Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Rosalind C. Williamson"'
Autor:
Christopher A. M. Cowell, Mark D. Bass, James A. Roper, Rosalind C. Williamson, Thomas Rendall, Thomas Reville
Publikováno v:
The Journal of Biological Chemistry
Background: Directional migration requires removal of Rac1 from the back of the cell. Results: Coronin-1C and caveolin provide parallel pathways for constitutive recycling or fibronectin-inducible degradation of Rac1. Discussion: Redundant traffickin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a18cdb0f9983be4434397a1161dc34cc
http://europepmc.org/articles/PMC4505459
http://europepmc.org/articles/PMC4505459
Publikováno v:
Small GTPases
Upon wounding, syndecan-4 detects the appearance of fibronectin in the wound bed and mediates regulation of the small GTPases, Rac1, RhoA and RhoG. Cohesive regulation of these molecules results in cycles of membrane protrusion and cytoskeletal contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b1e1c13437cc29a38c234c4ebc629c2
https://doi.org/10.4161/sgtp.19301
https://doi.org/10.4161/sgtp.19301
Publikováno v:
The Journal of Physiology. 590:2009-2034
The renal electrogenic Na(+)/HCO(3)(−) cotransporter (NBCe1-A) contributes to the basolateral step of transepithelial HCO(3)(−) reabsorption in proximal tubule epithelia, contributing to the buffering of blood pH. Elsewhere in the body (e.g. musc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65699052c2a426462824d172b1c6723d
https://doi.org/10.1113/jphysiol.2011.224733
https://doi.org/10.1113/jphysiol.2011.224733
Autor:
Paul Martin, Mark D. Bass, Robert Nunan, Martin J. Humphries, Adam Byron, Jonathan D. Humphries, Rosalind C. Williamson, Mark R. Morgan
Publikováno v:
Developmental Cell
Summary Cell migration during wound healing requires adhesion receptor turnover to enable the formation and disassembly of cell-extracellular matrix contacts. Although recent advances have improved our understanding of integrin trafficking pathways,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9380bfea794bb4ca969e133023f84d75
Publikováno v:
Blood Cells, Molecules, and Diseases. 45:1-8
The bicarbonate/chloride exchanger band 3 (Anion Exchanger 1, AE1) is the most abundant protein in the erythrocyte membrane, it has an important role in gas exchange and functions as a point of attachment for the cytoskeletons maintaining the mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ecb3b1a1bed40539a276389b8a64792
https://doi.org/10.1016/j.bcmd.2010.02.019
https://doi.org/10.1016/j.bcmd.2010.02.019
Autor:
Ashley M. Toye, Rosalind C. Williamson
Publikováno v:
Blood Cells, Molecules, and Diseases. 41:35-43
Band 3 (B3) is a major site of cytoskeletal attachment to the erythrocyte membrane and is important for gas exchange. A truncated isoform of B3 (kB3) is expressed in the alpha-intercalated cells of the kidney and its functional activity and basolater
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::943aa08c38900230665b17f426369dab
https://doi.org/10.1016/j.bcmd.2008.01.001
https://doi.org/10.1016/j.bcmd.2008.01.001
Autor:
Ashley M. Toye, Jean Delaunay, Brigitte Bader-Meunier, Moudji Khanfar, Gil Tchernia, Madeleine Thibault, Thérèse Cynober, Lesley J. Bruce, Rosalind C. Williamson, Michèle Dechaux
Publikováno v:
Blood
We describe a mutation in human erythrocyte band 3 (anion exchanger 1; SLC4A1) causing both hereditary spherocytosis and distal renal tubular acidosis. The proband developed a transfusion-dependent, hemolytic anemia following birth. Immunoblotting sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba28f26630c15a8d7d5e13e63d892a8
https://doi.org/10.1182/blood-2007-07-099473
https://doi.org/10.1182/blood-2007-07-099473
Autor:
Philip Stephens, James A. Roper, Rebecca Brooks, Andrew Harrison, Mark D. Bass, Christopher A. M. Cowell, Rosalind C. Williamson, Blandine Bally
Publikováno v:
The Journal of investigative dermatology. 135(11)
Chronic skin-healing defects are one of the leading challenges to lifelong well-being, affecting 2–5% of populations. Chronic wound formation is linked to age and diabetes and frequently leads to major limb amputation. Here we identify a strategy t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1625ea9ec759cc29a1ad6efd35085afe
https://pubmed.ncbi.nlm.nih.gov/26079528
https://pubmed.ncbi.nlm.nih.gov/26079528
Autor:
Rosalind C, Williamson, Christopher A M, Cowell, Christina L, Hammond, Dylan J M, Bergen, James A, Roper, Yi, Feng, Thomas C S, Rendall, Paul R, Race, Mark D, Bass
Publikováno v:
Journal of Cell Science
Sustained forward migration through a fibrillar extracellular matrix requires localization of protrusive signals. Contact with fibronectin at the tip of a cell protrusion activates Rac1, and for linear migration it is necessary to dampen Rac1 activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::531f28031d3b66b76b69725f19231c07
https://pubmed.ncbi.nlm.nih.gov/25074804
https://pubmed.ncbi.nlm.nih.gov/25074804
Autor:
Seth L. Alper, Simone M. Blattner, Timothy J. Satchwell, Mark T. Young, Nicola B. Kampik, Tibor Toth, Graham White, Mark D. Parker, Rosalind C. Williamson, Moin A. Saleem, Lan Ni, Carsten A. Wagner, Fiona Wu, Ashley M. Toye
Publikováno v:
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
The central role of the multifunctional protein nephrin within the macromolecular complex forming the glomerular slit diaphragm is well established, but the mechanisms linking the slit diaphragm to the cytoskeleton and to the signaling pathways invol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c96b2ce4905e34dc920989f636bc9495
https://europepmc.org/articles/PMC3013520/
https://europepmc.org/articles/PMC3013520/
