Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Rosalind B. Penney"'
Autor:
Patrick L. Apopa, Lisa Alley, Rosalind B. Penney, Konstantinos Arnaoutakis, Mathew A. Steliga, Susan Jeffus, Emine Bircan, Banu Gopalan, Jing Jin, Preecha Patumcharoenpol, Piroon Jenjaroenpun, Thidathip Wongsurawat, Nishi Shah, Gunnar Boysen, David Ussery, Intawat Nookaew, Pebbles Fagan, Gurkan Bebek, Mohammed S. Orloff
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Non-small cell lung cancer (NSCLC) is the major form of lung cancer, with adenocarcinoma (LUAD) and squamous cell carcinoma (LUSC) being its major subtypes. Smoking alone cannot completely explain the lung cancer etiology. We hypothesize that altered
Externí odkaz:
https://doaj.org/article/dd7d61d8be274cdb9f23954448c017ee
Autor:
Athena Starlard-Davenport, Mohammed S Orloff, Ishwori Dhakal, Rosalind B Penney, Susan A Kadlubar
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117347 (2015)
CYP19A1 facilitates the bioconversion of estrogens from androgens. CYP19A1 intron single nucleotide polymorphisms (SNPs) may alter mRNA splicing, resulting in altered CYP19A1 activity, and potentially influencing disease susceptibility. Genetic studi
Externí odkaz:
https://doaj.org/article/2d694c60066c46f5ad3d4c747d971a0e
Autor:
Daniel R. Sappington, Susanne K. Jeffus, Scott Helms, Thaddeus Bartter, Teka Bartter, Eric R. Siegel, Rosalind B. Penney, Gunnar Boysen
Publikováno v:
Cancer treatment and research communications. 14
Background Treatment of lung cancer is evolving from the use of cytotoxic drugs to drugs that interrupt pathways specific to a malignancy. The field of metabolomics has promise with respect to identification of tumor-specific processes and therapeuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f41bf2dbacfb2d72e719df7f6b0f94d0
https://pubmed.ncbi.nlm.nih.gov/30104001
https://pubmed.ncbi.nlm.nih.gov/30104001
Publikováno v:
International Journal of Environmental Research and Public Health, Vol 14, Iss 3, p 265 (2017)
International Journal of Environmental Research and Public Health
International Journal of Environmental Research and Public Health
Background: Children must be recognized as a sensitive population based on having biological systems and organs in various stages of development. The processes of absorption, distribution, metabolism and elimination of environmental contaminants with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28b854c556d99fd5e20b4c363224459f
http://www.mdpi.com/1660-4601/14/3/265
http://www.mdpi.com/1660-4601/14/3/265
Autor:
Rosalind B. Penney, Aiwei Yao-Borengasser, Martha L. Slattery, Roger K. Wolff, Vineetha Koroth Edavana, Ishwori Dhakal, Abbie Lundgreen, Suzanne Williams, Susan Kadlubar
Publikováno v:
Pharmacogenomics and Personalized Medicine
Rosalind B Penney,1 Abbie Lundgreen,2 Aiwei Yao-Borengasser,3 Vineetha K Edavana,3 Suzanne Williams,3 Ishwori Dhakal,4 Roger K Wolff,2 Susan Kadlubar,3 Martha L Slattery2 1Department of Environmental and Occupational Health, University of Arkansas fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0ce8005b52d68306436bb3ce84eb49e
http://europepmc.org/articles/PMC4109316
http://europepmc.org/articles/PMC4109316
Autor:
Aiwei Yao-Borengasser, Vineetha Koroth Edavana, Ishwori Dhakal, Gunnar Boysen, Susan Kadlubar, Suzanne Williams, Rosalind B. Penney
Publikováno v:
Drug Metabolism and Disposition. 41:870-877
Anastrozole belongs to the nonsteroidal triazole-derivative group of aromatase inhibitors. Recently, clinical trials demonstrated improved antitumoral efficacy and a favorable toxicity with third-generation aromatase inhibitors, compared with tamoxif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b57f8f6de1340258a31b8cc73e094ae9
https://doi.org/10.1124/dmd.112.048157
https://doi.org/10.1124/dmd.112.048157
Autor:
Robert J. Griffin, Daniel R. Sappington, Gunnar Boysen, Gloria Hiatt, Azemat Jamshidi-Parsian, Rosalind B. Penney, Eric R. Siegel, Abhishek Desai
Background Increased glutamine uptake is known to drive cancer cell proliferation, making tumor cells glutamine-dependent. Glutamine provides additional carbon and nitrogen sources for cell growth. The first step in glutamine utilization is its conve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::637f778ad2de463181985361e60bef3f
https://europepmc.org/articles/PMC4768472/
https://europepmc.org/articles/PMC4768472/
Autor:
Athena Starlard-Davenport, Aiwei Yao-Borengasser, Susan Kadlubar, Rosalind B. Penney, Vineetha Koroth Edavana, Ishwori Dhakal
Publikováno v:
International Journal of Cancer Research and Molecular Mechanisms ( ISSN 2381-3318 ). 1
Anastrozole is an aromatase inhibitor (AI) used as adjuvant therapy for breast cancer. Anastrozole is subject to direct glucuronidation catalyzed by UDP-glucuronosyltransferase1A4 (UGT1A4). Interindividual variability in anastrozole glucuronidation m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0986864107d1e83862588668ab315550
https://doi.org/10.16966/2381-3318.112
https://doi.org/10.16966/2381-3318.112
Publikováno v:
International journal of molecular epidemiology and genetics. 5(2)
Background: Candidate pathway approaches in disease association studies often utilize a tagSNP approach to capture genetic variation. In this paper we assess gene expression patterns with SNPs in genes in the CHIEF pathway to help determine their pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::89dec93a7001b51f348bdd2aae9a72b5
https://pubmed.ncbi.nlm.nih.gov/24959314
https://pubmed.ncbi.nlm.nih.gov/24959314
Autor:
Aiwei Yao-Borengasser, Susan Kadlubar, Vineetha Koroth Edavana, Suzanne Williams, Ishwori Dhakal, Lora J. Rogers, Rosalind B. Penney
Publikováno v:
SpringerPlus
Fulvestrant (Faslodex™) is a pure antiestrogen that is effective in treating estrogen receptor-(ER) positive breast cancer tumors that are resistant to selective estrogen receptor modulators such as tamoxifen. Clinical trials investigating the util
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9545623544e9ca09472e1d8a8fbec2a0
http://europepmc.org/articles/PMC3841332
http://europepmc.org/articles/PMC3841332