Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Rosalin H. Arends"'
Autor:
Anthony W. Tolcher, Rosalin H. Arends, Louis M. Weiner, Gisela Schwab, Rafael G. Amado, Arie S. Belldegrun, Pamela Lockbaum, Jeffrey Crawford, Robert A. Figlin, Lynn Navale
Publikováno v:
Clinical Cancer Research. 14:502-508
Purpose: This phase 1 study evaluated the safety, pharmacokinetics, and activity of panitumumab, a fully human, IgG2 monoclonal antibody that targets the epidermal growth factor receptor in patients with previously treated epidermal growth factor rec
Autor:
John A. Thompson, Naomi B. Haas, Jared A. Gollob, Garry Schwartz, Eric K. Rowinsky, Nicholas J. Vogelzang, Robert A. Figlin, Rosalin H. Arends, Kenneth A. Foon, Yu Ping Li, Pamela Lockbaum, Ronald M. Bukowski, Gisela Schwab, Janice P. Dutcher
Publikováno v:
Journal of Clinical Oncology. 22:3003-3015
PurposeTo determine the antitumor activity of ABX-EGF, a fully human monoclonal antibody to the epidermal growth factor receptor (EGFr), in previously treated patients with metastatic renal cell carcinoma, and to characterize its toxicity, immunogeni
Publikováno v:
Anesthesiology. 92:739-753
Background Despite widespread use, little is known about the comparative pharmacokinetics of intrathecally administered opioids. The present study was designed to characterize the rate and extent of opioid distribution within cerebrospinal fluid, spi
Autor:
Rosalin H. Arends, Gail A. Van Norman, Danny D. Shen, Janet D. Pavlin, Holly C. Gunn, Meagan E. Koerschgen
Publikováno v:
Anesthesiology. 91:97-108
Background The combination of propofol and alfentanil with nitrous oxide provides balanced anesthesia with rapid recovery and minimal emetic side effects. The object of this study was to compare recovery parameters at varying proportions of propofol
Publikováno v:
Epilepsy research. 18(2)
An earlier pharmacodynamic study of the chiral antiepileptic drug stiripentol in an intravenous pentylenetetrazol-induced seizure model in the rat showed the development of a significant degree of tolerance to the anticonvulsant and neurotoxic effect
Autor:
Rosalin H. Arends, Louis M. Weiner, Arie S. Belldegrun, Pamela Lockbaum, Eric K. Rowinsky, Gisela Schwab, Robert A. Figlin, S. Huang, J. Crawford
Publikováno v:
Journal of Clinical Oncology. 23:3059-3059
3059 Background: Panitumumab is a fully human monoclonal antibody to the epidermal growth factor receptor (EGFr). This open-label, multiple-infusion, dose-escalation trial evaluated the safety, pharmacokinetics (PK), and antitumor activity of panitum
Publikováno v:
Journal of Clinical Oncology. 23:3089-3089
3089 Background Panitumumab is a fully human monoclonal antibody directed against the EGFr. In a Phase 1 trial in patients with colorectal, NSCL, renal, prostate, pancreatic, or esophageal cancer, ...
Autor:
Rosalin H. Arends, Meagan E. Koerschgen, G. A. Van Norman, Danny D. Shen, Janet D. Pavlin, Holly C. Gunn
Publikováno v:
Anesthesiology. 87:308A