Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Rosalie G Hoyle"'
Autor:
Wenjin Wang, Bokai Yun, Rosalie G Hoyle, Zhikun Ma, Shadid Uz Zaman, Gan Xiong, Chen Yi, Nan Xie, Ming Zhang, Xiqiang Liu, Dipankar Bandyopadhyay, Jiong Li, Cheng Wang
Publikováno v:
Advanced Science, Vol 11, Iss 4, Pp n/a-n/a (2024)
Abstract Tumor budding (TB) is a small tumor cell cluster with highly aggressive behavior located ahead of the invasive tumor front. However, the molecular and biological characteristics of TB and the regulatory mechanisms governing TB phenotypes rem
Externí odkaz:
https://doaj.org/article/f651aeea1f5547538cc62c069850f3d1
Autor:
Brittany A Martínez, Rosalie G Hoyle, Scott Yeudall, Mitchell E Granade, Thurl E Harris, J David Castle, Norbert Leitinger, Michelle L Bland
Publikováno v:
PLoS Genetics, Vol 16, Iss 11, p e1009192 (2020)
During infection, cellular resources are allocated toward the metabolically-demanding processes of synthesizing and secreting effector proteins that neutralize and kill invading pathogens. In Drosophila, these effectors are antimicrobial peptides (AM
Externí odkaz:
https://doaj.org/article/68fbace5dc1f44709095beda0b986904
Publikováno v:
Cancer Immunology Research. 11:290-305
Accumulating evidence shows that PD-L1 expression on dendritic cells (DC) is critical for cancer immunotherapy and that Porphyromonas gingivalis (Pg) colonization aggravates the progression of upper gastrointestinal cancers. However, the effects of P
Autor:
Ming Zhang, Ganping Wang, Zhikun Ma, Gan Xiong, Wenjin Wang, Zhengxian Huang, Yuehan Wan, Xiuyun Xu, Rosalie G. Hoyle, Chen Yi, Jinsong Hou, Xiqiang Liu, Demeng Chen, Jiong Li, Cheng Wang
Publikováno v:
Molecular Therapy. 30:3394-3413
BET inhibition has been shown to have a promising antitumor effect in multiple tumors. However, the impact of BET inhibition on antitumor immunity was still not well documented in HNSCC. In this study, we aim to assess the functional role of BET inhi
Accumulating evidence shows that PD-L1 expression on dendritic cells (DC) is critical for cancer immunotherapy and that Porphyromonas gingivalis (Pg) colonization aggravates the progression of upper gastrointestinal cancers. However, the effects of P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b2c126c7cbc17e0bc78af502aea9f63
https://doi.org/10.1158/2326-6066.c.6551141.v1
https://doi.org/10.1158/2326-6066.c.6551141.v1
Expression of PD-1 and secretion of IL-2 by CD3+CD8+ cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::109d5413a69d37994f7fd84347a459be
https://doi.org/10.1158/2326-6066.22546313.v1
https://doi.org/10.1158/2326-6066.22546313.v1
Publikováno v:
Frontiers in Cell and Developmental Biology. 10
Emerging evidence indicates that the cellular electromagnetic field regulates the fundamental physics of cell biology. The electromagnetic oscillations and synchronization of biomolecules triggered by the internal and external pulses serve as the phy
Publikováno v:
Mol Cancer Ther
Epigenetic activation of Wnt/β-catenin signaling plays a critical role in Wnt-induced tumorigenesis, notably in colorectal cancers. KDM3 and KDM4 histone demethylases have been reported to promote oncogenic Wnt signaling through demethylation of H3K
Publikováno v:
FEBS Lett
Programmed death-ligand 1 (PD-L1) is critical for cancer cells ability to evade attacks from the host immune system. However, the molecular mechanisms controlling the PD-L1 expression have not been fully understood. Here, we demonstrate that Sorting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32003a7b051611fbfc68930b427e3d36
https://europepmc.org/articles/PMC8545913/
https://europepmc.org/articles/PMC8545913/
Autor:
Rosalie G. Hoyle, Andrew Morris, Piyusha Pagare, Shadid Uz Zaman, Zhikun Ma, Yan Zhang, Jiong Li
Publikováno v:
Cancer Research. 82:1862-1862
In this study, we performed a structure-activity-relationship study of seven previously identified chloro-naphthoquinone analogs and evaluated their abilities to inhibit the Wnt/β-catenin signaling pathway. The Wnt/β-catenin signaling pathway plays