Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Rosalie, De Beaumont"'
Autor:
Michael R. Schlabach, Frank Stegmeier, Tobias Schmelzle, William R. Sellers, Francesco Hofmann, Nicholas Keen, E. Robert McDonald, Audrey Kauffmann, Odile Weber, Rosalie de Beaumont, Daniel Rakiec, Sarah Y. Neshat, Matthew D. Shirley, Jessica Wan, Dorothee Abramowski, Antoine DeWeck, Gregory McAllister, Kristine Yu, David A. Ruddy, Javad Golji, Michael D. Jones, Joshua M. Korn, Eric Billy, Li Li, Pamela J. Cassiani, Diana M. Munoz
Correlation analysis matrix displaying features that correlate most strongly with sgRNA's having off target effects.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7173657ab8c9cebbe2e61d7645ea2b63
https://doi.org/10.1158/2159-8290.22531563.v1
https://doi.org/10.1158/2159-8290.22531563.v1
Autor:
Michael R. Schlabach, Frank Stegmeier, Tobias Schmelzle, William R. Sellers, Francesco Hofmann, Nicholas Keen, E. Robert McDonald, Audrey Kauffmann, Odile Weber, Rosalie de Beaumont, Daniel Rakiec, Sarah Y. Neshat, Matthew D. Shirley, Jessica Wan, Dorothee Abramowski, Antoine DeWeck, Gregory McAllister, Kristine Yu, David A. Ruddy, Javad Golji, Michael D. Jones, Joshua M. Korn, Eric Billy, Li Li, Pamela J. Cassiani, Diana M. Munoz
Locus-specific primer pairs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1709535e7c02d2f5f5842d5ce9819973
https://doi.org/10.1158/2159-8290.22531551.v1
https://doi.org/10.1158/2159-8290.22531551.v1
Autor:
Michael R. Schlabach, Frank Stegmeier, Tobias Schmelzle, William R. Sellers, Francesco Hofmann, Nicholas Keen, E. Robert McDonald, Audrey Kauffmann, Odile Weber, Rosalie de Beaumont, Daniel Rakiec, Sarah Y. Neshat, Matthew D. Shirley, Jessica Wan, Dorothee Abramowski, Antoine DeWeck, Gregory McAllister, Kristine Yu, David A. Ruddy, Javad Golji, Michael D. Jones, Joshua M. Korn, Eric Billy, Li Li, Pamela J. Cassiani, Diana M. Munoz
Supplementary Figure Legends, Table Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb53e60107d91f1fd9557bb4a74a377e
https://doi.org/10.1158/2159-8290.22531569
https://doi.org/10.1158/2159-8290.22531569
Autor:
Michael R. Schlabach, Frank Stegmeier, Tobias Schmelzle, William R. Sellers, Francesco Hofmann, Nicholas Keen, E. Robert McDonald, Audrey Kauffmann, Odile Weber, Rosalie de Beaumont, Daniel Rakiec, Sarah Y. Neshat, Matthew D. Shirley, Jessica Wan, Dorothee Abramowski, Antoine DeWeck, Gregory McAllister, Kristine Yu, David A. Ruddy, Javad Golji, Michael D. Jones, Joshua M. Korn, Eric Billy, Li Li, Pamela J. Cassiani, Diana M. Munoz
Annotations for the sgRNA libraries containing sequences, target gene information, Zscore and RNAseq data for each cell line screened.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8168764e4a5b7839ac54b7f252bfc00d
https://doi.org/10.1158/2159-8290.22531560
https://doi.org/10.1158/2159-8290.22531560
Autor:
Michael R. Schlabach, Frank Stegmeier, Tobias Schmelzle, William R. Sellers, Francesco Hofmann, Nicholas Keen, E. Robert McDonald, Audrey Kauffmann, Odile Weber, Rosalie de Beaumont, Daniel Rakiec, Sarah Y. Neshat, Matthew D. Shirley, Jessica Wan, Dorothee Abramowski, Antoine DeWeck, Gregory McAllister, Kristine Yu, David A. Ruddy, Javad Golji, Michael D. Jones, Joshua M. Korn, Eric Billy, Li Li, Pamela J. Cassiani, Diana M. Munoz
Supplementary Figure S1. Comparison of drop out phenotypes in MKN45, RKO, HT1080 highlighting selected pan-lethal genes. Supplementary Figure S2. The genes that scored as lethal by both RNAi and CRISPR were strongly enriched for known essential genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b398466e1fca85bee6e1c3e61c9c3ad
https://doi.org/10.1158/2159-8290.22531566
https://doi.org/10.1158/2159-8290.22531566
Autor:
Michael R. Schlabach, Frank Stegmeier, Tobias Schmelzle, William R. Sellers, Francesco Hofmann, Nicholas Keen, E. Robert McDonald, Audrey Kauffmann, Odile Weber, Rosalie de Beaumont, Daniel Rakiec, Sarah Y. Neshat, Matthew D. Shirley, Jessica Wan, Dorothee Abramowski, Antoine DeWeck, Gregory McAllister, Kristine Yu, David A. Ruddy, Javad Golji, Michael D. Jones, Joshua M. Korn, Eric Billy, Li Li, Pamela J. Cassiani, Diana M. Munoz
Annotations for the sgRNA/shRNA libraries containing average Zscore and copy number information.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::197327064184067f8b015ad082bcce37
https://doi.org/10.1158/2159-8290.22531557.v1
https://doi.org/10.1158/2159-8290.22531557.v1
Autor:
Pamela J. Cassiani, Odile Weber, E. Robert McDonald, Li Li, Sarah Y. Neshat, Diana M Munoz, Matthew D. Shirley, Javad Golji, William R. Sellers, Nicholas Keen, Rosalie de Beaumont, Joshua M. Korn, Eric Billy, Dorothee Abramowski, Kristine Yu, Gregory McAllister, Michael D. Jones, Audrey Kauffmann, David A. Ruddy, Jessica Wan, Daniel P. Rakiec, Frank Stegmeier, Francesco Hofmann, Tobias Schmelzle, Antoine deWeck, Michael R. Schlabach
Publikováno v:
Cancer Discovery. 6:900-913
CRISPR/Cas9 has emerged as a powerful new tool to systematically probe gene function. We compared the performance of CRISPR to RNAi-based loss-of-function screens for the identification of cancer dependencies across multiple cancer cell lines. CRISPR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1f6b84439c1cfc252c37fccb1285fae
https://doi.org/10.1158/2159-8290.cd-16-0178
https://doi.org/10.1158/2159-8290.cd-16-0178
Autor:
Jeffery L. Kutok, Rosalie de Beaumont, Giuliana Strola, Hervé Husson, Elizabeth G. Carideo, Angelo A. Cardoso, Olivier Munoz, Federico Caligaris-Cappio, Joachim L. Schultze, Arnold S. Freedman, Paolo Ghia
Publikováno v:
British Journal of Haematology. 119:492-495
Follicular lymphomas (FLs) localize in lymphoid tissues and recapitulate the structure of normal secondary follicles. The chemokine/chemokine receptor pair CXCL13/CXCR5 is required for the architectural organization of B cells within lymphoid follicl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f697a90855be3373b4cb15af477a434e
https://doi.org/10.1046/j.1365-2141.2002.03832.x
https://doi.org/10.1046/j.1365-2141.2002.03832.x
Publikováno v:
Leukemia & Lymphoma. 43:1663-1671
In this study, we report that the related adhesion focal tyrosine kinase RAFTK, is an upstream kinase in beta1 integrin mediated activation of Akt. Stimulation through beta1 integrins by fibronectin reversed apoptosis induced by adriamycin. Inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56499ca284433b54d82cb57ed55e9424
https://doi.org/10.1080/1042819021000003009
https://doi.org/10.1080/1042819021000003009
Autor:
Hervé, Husson, Arnold S, Freedman, Angelo A, Cardoso, Joachim, Schultze, Olivier, Munoz, Giuliana, Strola, Jeffery, Kutok, Elizabeth G, Carideo, Rosalie, De Beaumont, Federico, Caligaris-Cappio, Paolo, Ghia
Follicular lymphomas (FLs) localize in lymphoid tissues and recapitulate the structure of normal secondary follicles. The chemokine/chemokine receptor pair CXCL13/ CXCR5 is required for the architectural organization of B cells within lymphoid follic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::800f9e540f41488f8ea556675a73acab