Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Rosalia Stecconi"'
Publikováno v:
Biogerontology. 10:593-604
Aim of this study was to evaluate the effect of zinc on the kinetic of development of CD34(+) cell progenitors towards NK cells in young and old ages. CD34(+) cells were purified from peripheral blood of healthy subjects and cultured in medium supple
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 39:955-965
The Natural Killer cell maturation from CD34(+) hematopoietic cell precursors is a complex process that requires the synergistic effect of different cytokines and growth factors. Although there have been a number of important advances in our understa
Autor:
Silvia Tesei, Laura Costarelli, Mauro Provinciali, Giovanni Bernardini, Raffaella Moresi, C. Viticchi, Rosalia Stecconi
Publikováno v:
Biogerontology. 6:185-192
The aim of this study was to evaluate the peripheral representation and the clonogenic capacity of CD34(+) progenitor cells from 130 healthy subjects (80 females and 50 males) ranging in age from 16 to 100 years. We demonstrated that the absolute num
Autor:
Giuseppina Carrieri, Francesca Marchegiani, Fabiola Olivieri, Cinzia Molendini, Rosalia Stecconi, Chiara Trapassi, Giovanna De Benedictis, Dimitri Kletsas, Erika Marzi, Maurizio Cardelli, Luca Cavallone, Simona Giovagnetti, Claudio Franceschi
Publikováno v:
Aging Cell. 3:443-448
Sequence variations in a variety of pro- or anti-inflammatory cytokine genes have been found to influence successful aging and longevity. Because of the role played by the transforming growth factor beta1 (TGF-beta1) cytokine in inflammation and regu
Autor:
Maurizio Cardelli, Claudia Giampieri, Fabiola Olivieri, Raffaella Moresi, Rosamaria Lisa, Elena Mugianesi, Massimiliano Bonafè, Francesca Marchegiani, Luca Cavallone, Simona Giovagnetti, Claudio Franceschi, Rosalia Stecconi
Publikováno v:
Experimental Gerontology. 37:309-314
IL-6 in vitro production, as well as the serum/plasma concentration of the cytokine, increase with age. In the present investigation, a total of 62 individuals (31 males and 31 females), aged from 29 to 93 years of age (mean age of males: 60.4 years;
Autor:
Maurizio Cardelli, Maurizio Motta, Liana Spazzafumo, Paolo Sansoni, R. Rapisarda, Rosamaria Lisa, A.M. Franzone, C. Viticchi, Massimiliano Bonafè, L. Amadio, G. Sartoni, R. Mattace, L. Ferrucci, Paola Gueresi, G. De Benedictis, Silvana Valensin, R. Morresi, Fabiola Olivieri, Luca Deiana, Gabriella Pini, Cristiana Barbi, Luca Cavallone, Claudio Franceschi, Gianni Pes, Luciano Motta, M. Berardelli, Claudia Gemelli, Francesca Marchegiani, Maria Speranza Desole, Andrea Cossarizza, L. Troiano, Daniela Monti, Ciriaco Carru, Giovanni Passeri, S. Giunta, G. Baggio, Francesco Lescai, Rosalia Stecconi
Publikováno v:
Scopus-Elsevier
Gender accounts for important differences in the incidence and prevalence of a variety of age-related diseases. Considering people of far advanced age, demographic data document a clear-cut prevalence of females compared to males, suggesting that sex
Autor:
Giuseppina, Carrieri, Erika, Marzi, Fabiola, Olivieri, Francesca, Marchegiani, Luca, Cavallone, Maurizio, Cardelli, Simona, Giovagnetti, Rosalia, Stecconi, Cinzia, Molendini, Chiara, Trapassi, Giovanna, De Benedictis, Dimitri, Kletsas, Claudio, Franceschi
Publikováno v:
Aging cell. 3(6)
Sequence variations in a variety of pro- or anti-inflammatory cytokine genes have been found to influence successful aging and longevity. Because of the role played by the transforming growth factor beta1 (TGF-beta1) cytokine in inflammation and regu
Autor:
Rosamaria Lisa, Simona Giovagnetti, Lorenzo Falsetti, Claudio Franceschi, Matteo Centurelli, Liana Spazzafumo, Stefano Salvioli, C. Viticchi, Elena Mugianesi, Raffaella Moresi, Fabiola Olivieri, Silvia Tesei, Luca Cavallone, Massimiliano Bonafè, Claudia Giampieri, Maurizio Cardelli, Giuseppina Carrieri, Rosalia Stecconi, Francesca Marchegiani
Publikováno v:
Mechanisms of ageing and development. 124(4)
In the present investigation we analysed Interleukin 6 (IL-6) in vitro production by Epstein–Barr virus (EBV)-immortalized B lymphocytes established from 43 subjects, 15 young people and 28 elderly people, including 18 centenarians, after 3, 6, 9,
Autor:
Domenico Lio, Luigi M.E. Grimaldi, Rosalia Stecconi, Fabiola Olivieri, Grazia Di Stasio, Giovanna De Benedictis, Simona Giovagnetti, Claudio Franceschi, Claudia Giampieri, Calogero Caruso, Elena Mugianesi, Francesca L. Sciacca, Francesca Marchegiani, Massimiliano Bonafè, Maurizio Cardelli, Luca Cavallone
Publikováno v:
Mechanisms of ageing and development. 124(4)
In this study, we analysed the polymorphic variants of IL-1alpha (C-T transition at position -889), IL-1beta (C-T transition at position -511) and IL-1 receptor antagonist (Ra) (86-bp repeated sequence in intron 2) in 1131 subjects (453 females and 6
Autor:
Katia Altomare, Claudio Franceschi, Giuseppe Passarino, Peter A. Underhill, Giovanna De Benedictis, Rosalia Stecconi, Serena Dato, Gianpiero L. Cavalleri, L. Luca Cavalli Sforza, Valentina Greco
Publikováno v:
Human mutation. 21(5)
Understanding DNA variation within the human genome is fundamental to the identification and interpretation of genetic components underlying complex traits and diseases. Despite their role in many crucial cellular pathways and their reported involvem