Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rosalia Matteo"'
Autor:
Nicole O'Brien, S. Tarran Jones, David G. Williams, H. Brad Cunningham, Kelli Moreno, Barbara Visentin, Angela Gentile, John Vekich, William Shestowsky, Masao Hiraiwa, Rosalia Matteo, Amy Cavalli, Douglas Grotjahn, Maria Grant, Geneviève Hansen, Mary-Ann Campbell, Roger Sabbadini
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 11, Pp 2245-2257 (2009)
Sphingosine-1-phosphate (S1P) is a pleiotropic bioactive lipid involved in multiple physiological processes. Importantly, dysregulated S1P levels are associated with several pathologies, including cardiovascular and inflammatory diseases and cancer.
Externí odkaz:
https://doaj.org/article/ec8f3648f48c40f293d4a40be6d4c008
Autor:
Jie Su, Emerson Krock, Swapnali Barde, Ada Delaney, Johnny Ribeiro, Jungo Kato, Nilesh Agalave, Gustaf Wigerblad, Rosalia Matteo, Roger Sabbadini, Anna Josephson, Jerold Chun, Kim Kultima, Olivier Peyruchaud, Tomas Hökfelt, Camilla I. Svensson
Publikováno v:
Brain, Behavior, and Immunity
Brain, Behavior, and Immunity, 2022, 101, pp.214-230. ⟨10.1016/j.bbi.2022.01.003⟩
Brain, Behavior, and Immunity, 2022, 101, pp.214-230. ⟨10.1016/j.bbi.2022.01.003⟩
International audience; Inflammatory and neuropathic-like components underlie rheumatoid arthritis (RA)-associated pain, and lysophosphatidic acid (LPA) is linked to both joint inflammation in RA patients and to neuropathic pain. Thus, we investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b29dc2d42c562e763464fb315e36c2d0
https://www.hal.inserm.fr/inserm-03847767
https://www.hal.inserm.fr/inserm-03847767
Thrombin receptor and RhoA mediate cell proliferation through integrins and cysteine‐rich protein 61
Autor:
Dwayne G. Stupack, Rosalia Matteo, Colin Walsh, Julie Radeff-Huang, Albert Hsiao, Joan Heller Brown, Shankar Subramaniam
Publikováno v:
The FASEB Journal. 22:4011-4021
A subset of G-protein coupled receptors (GPCRs), including the thrombin receptor (PAR1), elicits mitogenic responses. Thrombin also activates Ras homolog gene family member A (RhoA) and activating protein (AP-1) -mediated gene expression in 1321N1 as
Publikováno v:
Journal of Cellular Biochemistry. 92:949-966
Agonist activation of a subset of G protein coupled receptors (GPCRs) stimulates cell proliferation, mimicking the better known effects of tyrosine kinase growth factors. Cell survival or apoptosis is also regulated via pathways initiated by stimulat
Autor:
Roger A. Sabbadini, Amy L. Cavalli, Yiling Lu, Shuangxing Yu, John A. Vekich, Barbara Visentin, Kelli Moreno, Vikas Kundra, Hassan Hall, Rosalia Matteo, Gordon B. Mills, Bradley J. Sibbald, William A. Garland
Publikováno v:
Cancer cell. 9(3)
SummaryS1P has been proposed to contribute to cancer progression by regulating tumor proliferation, invasion, and angiogenesis. We developed a biospecific monoclonal antibody to S1P to investigate its role in tumorigenesis. The anti-S1P mAb substanti
Autor:
Roger A. Sabbadini, Alice Pébay, Graham J. Lieschke, Frisca Frisca, Felix Ellett, Kelli Moreno, Rosalia Matteo, Peter D. Currie, Duncan E. Crombie, Tamar E. Sztal, Yona Goldshmit
Publikováno v:
The American Journal of Pathology. (3):978-992
Evidence suggests a proinflammatory role of lysophosphatidic acid (LPA) in various pathologic abnormalities, including in the central nervous system. Herein, we describe LPA as an important mediator of inflammation after spinal cord injury (SCI) in z