Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Rosa Viñas-Castells"'
Autor:
Natàlia Dave, Rosa Viñas-Castells, Alex Frias, Guillem Lambies, Antonio García de Herreros, Víctor M. Díaz, Catalina Martínez-Guillamon
Publikováno v:
Molecular and Cellular Biology. 36:923-940
Notch activation in aortic endothelial cells (ECs) takes place at embryonic stages during cardiac valve formation and induces endothelial-to-mesenchymal transition (EndMT). Using aortic ECs, we show here that active Notch expression promotes EndMT, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd3eca34d622166052dcc5a5b025fc1
https://doi.org/10.1128/mcb.01074-15
https://doi.org/10.1128/mcb.01074-15
Publikováno v:
Cell Adhesion & Migration. 8:418-428
The epithelial to mesenchymal transition (EMT) consists of a rapid change of cell phenotype, characterized by the loss of epithelial characteristics and the acquisition of a more invasive phenotype. Transcription factors regulating EMT (Snail, Twist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b5ec6ba82f95e1858c45153ec468bc
https://doi.org/10.4161/19336918.2014.969998
https://doi.org/10.4161/19336918.2014.969998
Publikováno v:
Bioconjugate Chemistry. 20:2262-2269
Control of gene expression via small interfering RNA has enormous potential for the treatment of a variety of diseases, including cancer and Huntington's disease. However, before any therapies can be developed, effective techniques for controlled del
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a63145a97f52dc52b67e59c3d2d7ab01
https://doi.org/10.1021/bc900241w
https://doi.org/10.1021/bc900241w
Autor:
J. Ignacio Casal, Alberto Peláez-García, María F. López-Lucendo, Antonio García de Herreros, Sofia Torres, Félix Bonilla, Rocco Mazzolini, Rubén Álvaro Bartolomé, Marta Mendes, Rosa Viñas-Castells, Raquel Batlle, Rodrigo Barderas
Adipogenesis requires a differentiation program driven by multiple transcription factors, where PPARγ and C/EBPα play a central role. Recent findings indicate that Snail inhibits adipocyte differentiation in 3T3-L1 and murine mesenchymal stem cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eefe90e65dec0ff1913aa7aba58d4f87
http://hdl.handle.net/10230/26177
http://hdl.handle.net/10230/26177
Autor:
Estefanía Robles-Lanuza, Kun Zhang, Antonio García de Herreros, Víctor M. Díaz, Alex Frias, Rosa Viñas-Castells, Gregory D. Longmore
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
Nucleic Acids Research
instname
Nucleic Acids Research
The zinc finger transcription factor Snail1 regulates epithelial to mesenchymal transition, repressing epithelial markers and activating mesenchymal genes. Snail1 is an extremely labile protein degraded by the cytoplasmic ubiquitin-ligases β-TrCP1/F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b8711910f57a8e49bf26f61c8033406
http://hdl.handle.net/10230/23346
http://hdl.handle.net/10230/23346
Autor:
Mireia Duñach, Sandra Peiró, Arantza Rodríguez-Asiain, A García de Herreros, B Del Valle-Pérez, Rosa Viñas-Castells, Víctor M. Díaz, Patricia Villagrasa, Jose M. Lizcano, J I Casal, Natàlia Dave
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
12 p.-7 fig.
Snail1 is a transcriptional factor essential for triggering epithelial-to-mesenchymal transition. Moreover, Snail1 promotes resistance to apoptosis, an effect associated to PTEN gene repression and Akt stimulation. In this article w
Snail1 is a transcriptional factor essential for triggering epithelial-to-mesenchymal transition. Moreover, Snail1 promotes resistance to apoptosis, an effect associated to PTEN gene repression and Akt stimulation. In this article w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ae421693eaf1f889d4ff38badb45e3e
http://hdl.handle.net/10261/50517
http://hdl.handle.net/10261/50517
Autor:
Félix Bonilla, Irene Gómez, Gabriela Valls, Josep Baulida, Rosa Viñas-Castells, Bàrbara Montserrat-Sentís, Víctor M. Díaz, Antonio García de Herreros, Manuel Beltran, José Miguel García
Publikováno v:
The Journal of biological chemistry. 285(6)
The transcription factor SNAIL1 is a master regulator of epithelial to mesenchymal transition. SNAIL1 is a very unstable protein, and its levels are regulated by the E3 ubiquitin ligase beta-TrCP1 that interacts with SNAIL1 upon its phosphorylation b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8afdcacf9f68467d0b180ba8e5a58774
https://pubmed.ncbi.nlm.nih.gov/19955572
https://pubmed.ncbi.nlm.nih.gov/19955572
Publikováno v:
Bioconjugate Chemistry; Dec2009, Vol. 20 Issue 12, p2262-2269, 8p