Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rosa Sebree"'
Autor:
Charles M. Rudin, Malcolm V. Brock, Stephen B. Baylin, James G. Herman, Steven A. Belinsky, Michelle A. Rudek, Igor Espinoza Delgado, Salina Tsai, Beverly Lee, Noreli Franco, Craig M. Hooker, Kristen Rodgers, Rosa Sebree, Barbara Coleman, Ming Zhao, Sara C. Murphy, Frank P. Vendetti, John Wrangle, Rosalyn A. Juergens
mp3 file (49.6MB). Patients with recurrent metastatic non-small cell lung cancer have a morbid prognosis, but a new epigenetic therapy may have potential for this population. Cancer Discovery Editors-in-Chief Jose Baselga, M.D., Ph.D. and Lewis C. Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::903e2d0eae26ec64c9c6ad1ff3eb7c7f
https://doi.org/10.1158/2159-8290.22529045
https://doi.org/10.1158/2159-8290.22529045
Autor:
Charles M. Rudin, Julie R. Brahmer, Jun O. Liu, David S. Ettinger, Ruth Smith, Peng Huang, Blake T. Aftab, Rosalyn A. Juergens, Christine L. Hann, Rosa Sebree
Publikováno v:
Journal of Thoracic Oncology. 8(5):619-623
Introduction Preclinical studies have suggested that the oral antifungal agent itraconazole specifically inhibits proliferation, migration, and tube formation of endothelial cells. Itraconazole has potent antiangiogenic activity and enhances the effi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7acc2fbfc265f5566cd3165544f010aa
Autor:
Rosalyn A. Juergens, Rosa Sebree, James G. Herman, Frank P. Vendetti, Ming Zhao, Charles M. Rudin, Noreli Franco, Steven A. Belinsky, Igor Espinoza Delgado, Barbara Coleman, Salina Tsai, Malcolm V. Brock, John Wrangle, Beverly Lee, Stephen B. Baylin, Craig M. Hooker, Kristen Rodgers, Sara C. Murphy, Michelle A. Rudek
Epigenetic alterations are strongly associated with the development of cancer. We conducted a phase I/II trial of combined epigenetic therapy with azacitidine and entinostat, inhibitors of DNA methylation and histone deacetylation, respectively, in e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ece3d36f59b6b734c4e86c4bef044d3
https://europepmc.org/articles/PMC3353724/
https://europepmc.org/articles/PMC3353724/
Autor:
Rosalyn A. Juergens, John Wrangle, Charles M. Rudin, James G. Herman, Barbara Coleman, Rosa Sebree, Steven A. Belinsky, Malcolm V. Brock, Stephen B. Baylin, Michelle Rudek-Renaut, Frank P. Vendetti
Publikováno v:
Cancer Research. 71:LB-411
Background: Epigenetic gene silencing is a key contributor to carcinogenesis. Pre-clinical studies suggest that combined inhibition of DNA methyltransferase and of histone deacetylase activity can synergistically re-express aberrantly silenced genes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::334d263567e99e8366c80f47d215dfa4
https://doi.org/10.1158/1538-7445.am2011-lb-411
https://doi.org/10.1158/1538-7445.am2011-lb-411
Autor:
S. Belinsky, Malcolm V. Brock, Stephen B. Baylin, Rosalyn A. Juergens, Rosa Sebree, Barbara Coleman, Charles M. Rudin, James P. Herman, Frank P. Vendetti, Michelle A. Rudek
Publikováno v:
Journal of Clinical Oncology. 27:8055-8055
8055 Background: Epigenetic gene silencing mediated through aberrant DNA methylation and histone deacetylation is a key contributor to lung carcinogenesis. Pre-clinical studies suggest that combining inhibitors of DNA methyltransferase (DNMT) with in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8b6ad2876a45a0f427dbeaf035ddf25
https://doi.org/10.1200/jco.2009.27.15_suppl.8055
https://doi.org/10.1200/jco.2009.27.15_suppl.8055
Autor:
Charles M. Rudin, Barbara Coleman, Rosa Sebree, Rosalyn A. Juergens, James G. Herman, Michelle A. Rudek, Frank P. Vendetti, Malcolm V. Brock, Stephen B. Baylin, Steven A. Belinsky
Publikováno v:
Journal of Clinical Oncology. 26:19036-19036
19036 Background: Epigenetic gene silencing is a key contributor to lung carcinogenesis. Pre-clinical studies suggest that combining inhibitors of DNA methyltransferase (DNMT) with inhibitors of hi...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec8fa1b91c2cdc16d320a0273015f7a4
https://doi.org/10.1200/jco.2008.26.15_suppl.19036
https://doi.org/10.1200/jco.2008.26.15_suppl.19036