Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Rosa SP"'
Autor:
Liza Grosman-Rimon, Leon Rivlin, Rosa Spataro, Zhiqiang Zhu, Jane Casey, Susan Tory, Jhanvi Solanki, Pete Wegier
Publikováno v:
Digital Health, Vol 10 (2024)
Introduction Sepsis alerts based on laboratory and vital sign criteria were found insufficient to improve patient outcomes. While most early sepsis alerts were implemented into smaller scale operating systems, a centralized new approach may provide m
Externí odkaz:
https://doaj.org/article/ea99c89c8ecc4c5494430c3ae7e7a561
Autor:
Michele Longo, Federica Zatterale, Rosa Spinelli, Jamal Naderi, Luca Parrillo, Pasqualina Florese, Cecilia Nigro, Alessia Leone, Augusta Moccia, Antonella Desiderio, Gregory A. Raciti, Claudia Miele, Ulf Smith, Francesco Beguinot
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-24 (2023)
Abstract Background First-degree relatives of type 2 diabetics (FDR) exhibit a high risk of developing type 2 diabetes (T2D) and feature subcutaneous adipocyte hypertrophy, independent of obesity. In FDR, adipose cell abnormalities contribute to earl
Externí odkaz:
https://doaj.org/article/67d0a5fc91c74ab8832d99e8826746b5
Autor:
Fabrizio Villapiano, Ritamaria Di Lorenzo, Rosa Sparaco, Elisa Magli, Francesco Frecentese, Sonia Laneri, Alessandra D’Orsi, Valeria Nele, Marco Biondi, Laura Mayol, Virginia Campani, Vincenzo Santagada, Giuseppe De Rosa
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 777 (2024)
Chronic wounds are marked by an extended healing period during which damaged tissues fail to undergo orderly and timely repair. Examples of chronic wounds encompass venous ulcers, pressure ulcers, and diabetic foot ulcers. The process of wound healin
Externí odkaz:
https://doaj.org/article/5e54e6a42b0f47028cbed75bebae7b29
Autor:
Rosa Sparaco, Pierfrancesco Cinque, Antonia Scognamiglio, Angela Corvino, Giuseppe Caliendo, Ferdinando Fiorino, Elisa Magli, Elisa Perissutti, Vincenzo Santagada, Beatrice Severino, Paolo Luciano, Marcello Casertano, Anna Aiello, Gustavo Yuri Martins Viegas, Gilberto De Nucci, Francesco Frecentese
Publikováno v:
Molecules, Vol 29, Iss 7, p 1598 (2024)
4-Nitro and 7-nitro propranolol have been recently synthesized and characterized by us. (±)-4-NO2-propranolol has been shown to act as a selective antagonist of 6-nitrodopamine (6-ND) receptors in the right atrium of rats. As part of our follow-up t
Externí odkaz:
https://doaj.org/article/1faca57576ae452e9550a466612b7446
Autor:
Rosa Spinelli, Ritesh Kumar Baboota, Silvia Gogg, Francesco Beguinot, Matthias Blüher, Annika Nerstedt, Ulf Smith
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 12 (2023)
Cell senescence (CS) is at the nexus between aging and associated chronic disorders, and aging increases the burden of CS in all major metabolic tissues. However, CS is also increased in adult obesity, type 2 diabetes (T2D), and nonalcoholic fatty li
Externí odkaz:
https://doaj.org/article/385566925a69478882f3d28fa1bafa44
Publikováno v:
BMC Health Services Research, Vol 22, Iss 1, Pp 1-14 (2022)
Abstract Background Rare disease patients and carers report significant impacts on mental health but studies on UK populations have focussed on relatively few, specific conditions. Collectively rare conditions represent a substantial health burden, w
Externí odkaz:
https://doaj.org/article/48010d04ebc845dc8ad4216c1d4a2313
Autor:
Giorgia Andreozzi, Maria Rosaria Ambrosio, Elisa Magli, Giovanni Maneli, Beatrice Severino, Angela Corvino, Rosa Sparaco, Elisa Perissutti, Francesco Frecentese, Vincenzo Santagada, Anna Leśniak, Magdalena Bujalska-Zadrożny, Giuseppe Caliendo, Pietro Formisano, Ferdinando Fiorino
Publikováno v:
Pharmaceuticals, Vol 16, Iss 10, p 1483 (2023)
Arylpiperazines represent one of the most important classes of 5-HT1AR ligands and have attracted considerable interests for their versatile properties in chemistry and pharmacology, leading to the research of new derivatives that has been focused on
Externí odkaz:
https://doaj.org/article/f809eadae0904facb28d7ccc4163c291
Autor:
Maria Rosaria Ambrosio, Elisa Magli, Giuseppe Caliendo, Rosa Sparaco, Paola Massarelli, Vittoria D’Esposito, Teresa Migliaccio, Giusy Mosca, Ferdinando Fiorino, Pietro Formisano
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-14 (2022)
Abstract Background Serotonin (or 5-Hydroxytryptamine, 5-HT) signals in mammary gland becomes dysregulated in cancer, also contributing to proliferation, metastasis, and angiogenesis. Thus, the discovery of novel compounds targeting serotonin signali
Externí odkaz:
https://doaj.org/article/1ff550da64d74d238fdea77957c3ed5d
Autor:
Ritesh K. Baboota, Rosa Spinelli, Malin C. Erlandsson, Bruna B. Brandao, Marsel Lino, Hong Yang, Adil Mardinoglu, Maria I. Bokarewa, Jeremie Boucher, C. Ronald Kahn, Ulf Smith
Publikováno v:
Molecular Metabolism, Vol 64, Iss , Pp 101558- (2022)
Objective: Cellular senescence, an irreversible proliferative cell arrest, is caused by excessive intracellular or extracellular stress/damage. Increased senescent cells have been identified in multiple tissues in different metabolic and other aging-
Externí odkaz:
https://doaj.org/article/82af05ba8e3a4d02a32750880a3b60a8
Autor:
Luca Parrillo, Rosa Spinelli, Michele Longo, Federica Zatterale, Gianluca Santamaria, Alessia Leone, Michele Campitelli, Gregory Alexander Raciti, Francesco Beguinot
Publikováno v:
Cells, Vol 12, Iss 16, p 2090 (2023)
The transcription factor HOXA5, from the HOX gene family, has long been studied due to its critical role in physiological activities in normal cells, such as organ development and body patterning, and pathological activities in cancer cells. Nonethel
Externí odkaz:
https://doaj.org/article/862612a4bea44cc08d945e65e8d35417