Výsledky vyhledávání - "Rosa Quiles-Pérez"

Akademický článek

Variation of transaminases, HCV-RNA levels and Th1/Th2 cytokine production during the post-partum period in pregnant women with chronic hepatitis C.

Autor: Angeles Ruiz-Extremera, José Antonio Muñoz-Gámez, Ana Abril-Molina, María Angustias Salmerón-Ruiz, Paloma Muñoz-de-Rueda, Esther José Pavón-Castillero, Rosa Quiles-Pérez, Angel Carazo, Ana Gila, Sergio Manuel Jimenez-Ruiz, Jorge Casado, Ana Belén Martín, Laura Sanjuán-Núñez, Esther Ocete-Hita, Julián López Viota, Josefa León, Javier Salmerón

Publikováno v: PLoS ONE, Vol 8, Iss 10, p e75613 (2013)

This study analyses the evolution of liver disease in women with chronic hepatitis C during the third trimester of pregnancy and the post-partum period, as a natural model of immune modulation and reconstitution. Of the 122 mothers recruited to this

Externí odkaz: https://doaj.org/article/13124762d536427a8355fe77d3351cff

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Seroprevalence and epidemiology of hepatitis B and C viruses in pregnant women in Spain. Risk factors for vertical transmission

Publikováno v: PLoS ONE, Vol 15, Iss 5, p e0233528 (2020)
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
PLoS ONE
Digibug. Repositorio Institucional de la Universidad de Granada
instname

Background & aim Worldwide, measures are being implemented to eradicate hepatitis B (HBV) and C (HCV) viruses, which can be transmitted from the mother during childbirth. This study aims to determine the prevalence of HBV and HCV in pregnant women in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::111e091d1bea1a41df5bf78d14e7cd2f
http://hdl.handle.net/10481/62704

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Expression and Single Nucleotide Polymorphism of Poly (ADPRibose) Polymerase-1 in Gastrointestinal Tumours: Clinical Involvement

Autor: Josefa León, Rosa Quiles-Pérez, Javier Salmerón, Laura Belmonte, José Antonio Muñoz-Gámez, David Martín-Oliva, Ángeles Ruiz-Extremera, Sandra M. Martín-Guerrero

Publikováno v: Current Medicinal Chemistry. 24

Poly(ADP-ribose) polymerase-1 (PARP-1) is a nuclear enzyme that plays a critical role in diverse cellular functions, such as DNA damage detection and repair, transcriptional regulation and cell death. Furthermore, PARP-1 has emerged as a key player i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9430b74b7304d3d4f2fc7bcb8f43950
https://doi.org/10.2174/0929867324666170316115039

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Hepatitis C virus NS5A region mutation in chronic hepatitis C genotype 1 patients who are non-responders to two or more treatments and its relationship with response to a new treatment

Autor: José Manuel Fuentes Rodríguez, Paloma Rueda, Angeles Ruíz Extremera, Rosa Quiles Pérez, Javier Salmerón, Jorge Casado Ruíz, Ana Gila Medina, Ana Belén Martín Álvarez

Publikováno v: World Journal of Gastroenterology

AIM To determine the number of mutations in the NS5A region of the hepatitis C virus (HCV) and its relationship to the response to antiviral therapy in patients with chronic hepatitis C genotype 1 who are non-responders to two or more treatments. MET

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b2d232d9b35272a401e304a0f8c793
https://hdl.handle.net/10668/11436

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Effects of ribavirin monotherapy on the viral population in patients with chronic hepatitis C genotype 1: Direct sequencing and pyrosequencing of the HCV regions

Autor: Paloma Muñoz-de-Rueda, Josep Quer, A. Martín-Álvarez, Javier Salmerón, Rosa Quiles-Pérez, A. Martín-Lagos Maldonado

Publikováno v: Journal of Medical Virology. 86:1886-1897

Ribavirin remains essential to chronic hepatitis C treatment. This paper investigates the influence of ribavirin priming to steady state before combined pegylated-interferon/ribavirin treatment on viral kinetics, ribavirin trough concentrations, gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e1889b7af48e770d0bb64278610d7392
https://doi.org/10.1002/jmv.24035

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Valor de la genética en la era de la terapia triple frente al virus de la hepatitis C

Autor: Javier Salmerón, Rosa Quiles-Pérez, Isabel Carmona, Esther José Pavón-Castillero, Paloma Muñoz-de-Rueda

Publikováno v: Gastroenterología y Hepatología. 37:427-437

Despite the introduction of protease inhibitors (PI) in the treatment of hepatitis C, the sensitivity of interferon continues to be essential to achieve a sustained virological response (SVR) and to eradicate the viral infection. Currently, pegylated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9ddfcd17eca9cb1e6b0523adbc4ad102
https://doi.org/10.1016/j.gastrohep.2014.04.004

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Inhibition of poly adenosine diphosphate-ribose polymerase decreases hepatocellular carcinoma growth by modulation of tumor-related gene expression

Autor: Ana Belén Martín-Álvarez, Ángeles Ruiz-Extremera, Raúl González, José Antonio Muñoz-Gámez, Rosa Quiles-Pérez, Laura Sanjuan-Nuñez, Jordi Muntané, Paloma Rueda, Josefa León, Francisco O'Valle, Francisco Javier Oliver, T. Caballero, Javier Salmerón, David Martín-Oliva

Publikováno v: Hepatology. 51:255-266

Hepatocellular carcinoma (HCC) is associated with a poor prognosis due to a lack of effective treatment options. In HCC a significant role is played by DNA damage and the inflammatory response. Poly (ADP-ribose) polymerase-1 (PARP-1) is an important

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92ba99aa0bd95a91afcef007ce0d3138
https://doi.org/10.1002/hep.23249

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High-Resolution Hepatitis C Virus Subtyping Using NS5B Deep Sequencing and Phylogeny, an Alternative to Current Methods

Publikováno v: Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Digital.CSIC. Repositorio Institucional del CSIC

All Rights Reserved. HepatitisCvirus(HCV)is classified into seven major genotypesand67 subtypes. Recent studies haveshownthat inHCVgenotype 1-infected patients, response rates to regimens containingdirect-acting antivirals(DAAs)are subtype dependent.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c74b90d1df6e26cb872ca91ea2428039
https://europepmc.org/articles/PMC4290919/

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