Zobrazeno 1 - 10
of 77
for search: '"Rosa Nguyen"'
Author/Creator:
Nan Zhang, Kevin Conlon, Donna Bernstein, Robert Somerville, Thomas Waldmann, Rosa Nguyen, Steven Highfill, Crystal L Mackall, David Stroncek, Sabina Kaczanowska, Julia Segal, Anh Dinh, Melinda S Merchant, Rosandra N Kaplan
Published in:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/25df833e7c744f0a8a4de685ddc03507
Author/Creator:
Nan Li, Haiying Qin, Rosa Nguyen, Mitchell Ho, Ming Sun, Eytan Ruppin, Michael C Kelly, Yingying Cao, Reona Okada, Jeyshka M Reyes-González, Hannah G Stack, Charlie Seibert, Carol J Thiele
Published in:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 1 (2023)
Background Although most patients with newly diagnosed high-risk neuroblastoma (NB) achieve remission after initial therapy, more than 50% experience late relapses caused by minimal residual disease (MRD) and succumb to their cancer. Therapeutic stra
Externí odkaz:
https://doaj.org/article/c2a4dbca004d4ad9aeecc39207e2e0f9
Published in:
Neoplasia: An International Journal for Oncology Research, Vol 26, Iss , Pp 100776- (2022)
Neuroblastoma accounts for 15% of cancer-related deaths in children, highlighting an unmet need for novel therapies. Selinexor is a small molecule inhibitor of XPO1. XPO1 shuffles cargo proteins with a nuclear export sequence from the nucleus to the
Externí odkaz:
https://doaj.org/article/f28c112ca9fd4ed981602df52c5319d8
Published in:
STAR Protocols, Vol 2, Iss 4, Pp 100942- (2021)
Summary: The translation of chimeric antigen receptor (CAR) T cell therapy for pediatric solid tumors is limited by the lack of preclinical models that fully recapitulate solid tumor biology. We describe steps to implement neuroblastoma metastatic an
Externí odkaz:
https://doaj.org/article/51b45698cd264ae3a0c1ea891efc33b3
Author/Creator:
Maged Zeineldin, Sara Federico, Xiang Chen, Yiping Fan, Beisi Xu, Elizabeth Stewart, Xin Zhou, Jongrye Jeon, Lyra Griffiths, Rosa Nguyen, Jackie Norrie, John Easton, Heather Mulder, Donald Yergeau, Yanling Liu, Jianrong Wu, Collin Van Ryn, Arlene Naranjo, Michael D. Hogarty, Marcin M. Kamiński, Marc Valentine, Shondra M. Pruett-Miller, Alberto Pappo, Jinghui Zhang, Michael R. Clay, Armita Bahrami, Peter Vogel, Seungjae Lee, Anang Shelat, Jay F. Sarthy, Michael P. Meers, Rani E. George, Elaine R. Mardis, Richard K. Wilson, Steven Henikoff, James R. Downing, Michael A. Dyer
Published in:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
In most cancers, mutations that lead to oncogene activation and tumor suppressor inactivation synergize to promote tumorigenesis. However, in neuroblastomas, MYCN amplification and ATRX mutations are mutually exclusive and incompatible.
Externí odkaz:
https://doaj.org/article/08a87c1bf95d4f798e9e0d5a7daabd61
Author/Creator:
Nan Li, Madeline B. Torres, Madeline R. Spetz, Ruixue Wang, Luyi Peng, Meijie Tian, Christopher M. Dower, Rosa Nguyen, Ming Sun, Chin-Hsien Tai, Natalia de Val, Raul Cachau, Xiaolin Wu, Stephen M. Hewitt, Rosandra N. Kaplan, Javed Khan, Brad St Croix, Carol J. Thiele, Mitchell Ho
Published in:
Cell Reports Medicine, Vol 2, Iss 6, Pp 100297- (2021)
Summary: Targeting solid tumors must overcome several major obstacles, in particular, the identification of elusive tumor-specific antigens. Here, we devise a strategy to help identify tumor-specific epitopes. Glypican 2 (GPC2) is overexpressed in ne
Externí odkaz:
https://doaj.org/article/1562370b31514de19b560ba348a2c0f6
Author/Creator:
Daniel Olson, Jiajia Zhang, Todd Bartkowiak, Abdul Rafeh Naqash, Vaia Florou, Rosa Nguyen, Rania H Younis, Sarah Church, Maria E Rodriguez-Ruiz, Rachel Howard, Thomas U Marron, Ravi B Patel, Michal Sheffer, Abigail Overacre-Delgoffe, Aideen E Ryan, Sangeetha M Reddy, Sabina Kaczanowska, Dipti Thakkar, Kristin G Anderson, Esha Sachdev, Christopher Fuhrman, Jessica E Thaxton, David H Aggen, Jennifer L Guerriero
Published in:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Immune checkpoint inhibitors (ICIs) have improved overall survival for cancer patients, however, optimal duration of ICI therapy has yet to be defined. Given ICIs were first used to treat patients with metastatic melanoma, a condition that at the tim
Externí odkaz:
https://doaj.org/article/7d235762c1ba404981eaf9960cd816b9
Author/Creator:
Rosa Nguyen, Huiyun Wu, Stanley Pounds, Hiroto Inaba, Raul C. Ribeiro, David Cullins, Barbara Rooney, Teresa Bell, Norman J. Lacayo, Kenneth Heym, Barbara Degar, Deborah Schiff, William E. Janssen, Brandon Triplett, Ching-Hon Pui, Wing Leung, Jeffrey E. Rubnitz
Published in:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-7 (2019)
Abstract Consolidation therapies for children with intermediate- or high-risk acute myeloid leukemia (AML) are urgently needed to achieve higher cure rates while limiting therapy-related toxicities. We determined if adoptive transfer of natural kille
Externí odkaz:
https://doaj.org/article/4196b54e9163489ba534ba9dc6b66a38
Author/Creator:
Scott R Plotkin, Miriam A Bredella, Wenli Cai, Ara Kassarjian, Gordon J Harris, Sonia Esparza, Vanessa L Merker, Lance L Munn, Alona Muzikansky, Manor Askenazi, Rosa Nguyen, Ralph Wenzel, Victor F Mautner
Published in:
PLoS ONE, Vol 7, Iss 4, p e35711 (2012)
Patients with neurofibromatosis 1 (NF1), NF2, and schwannomatosis are at risk for multiple nerve sheath tumors and premature mortality. Traditional magnetic resonance imaging (MRI) has limited ability to assess disease burden accurately. The aim of t
Externí odkaz:
https://doaj.org/article/fa01fa245d85418b9a10cfca1a9dd5da
Author/Creator:
Melanie Spyra, Lan Kluwe, Christian Hagel, Rosa Nguyen, Jens Panse, Andreas Kurtz, Victor Felix Mautner, Samuel David Rabkin, Maria Demestre
Published in:
PLoS ONE, Vol 6, Iss 6, p e21099 (2011)
This study aims to examine whether or not cancer stem cells exist in malignant peripheral nerve sheath tumors (MPNST). Cells of established lines, primary cultures and freshly dissected tumors were cultured in serum free conditions supplemented with
Externí odkaz:
https://doaj.org/article/56228b24137f4c71855b377bafd5a182