Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Rosa Marina MELILLO"'
Autor:
Immacolata Maietta, Eleonora Viscusi, Stefano Laudati, Giuseppe Iannaci, Antonio D’Antonio, Rosa Marina Melillo, Maria Letizia Motti, Valentina De Falco
Publikováno v:
Cells, Vol 13, Iss 18, p 1546 (2024)
In most human tumors, the MAPK pathway is constitutively activated. Since p90RSK is downstream of MAPK, it is often hyperactive and capable of phosphorylating oncogenic substrates. We have previously shown that p90RSK phosphorylates MDM2 at S166, pro
Externí odkaz:
https://doaj.org/article/0c2a3e54058746a697d85fc3189d255e
Autor:
Marco De Martino, Simona Pellecchia, Francesco Esposito, Federica Liotti, Sara Carmela Credendino, Nella Prevete, Myriam Decaussin-Petrucci, Paolo Chieffi, Gabriella De Vita, Rosa Marina Melillo, Alfredo Fusco, Pierlorenzo Pallante
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract Thyroid cancer is the most prevalent endocrine malignancy and comprises a wide range of lesions subdivided into differentiated (DTC) and undifferentiated thyroid cancer (UTC), mainly represented by the anaplastic thyroid carcinoma (ATC). Thi
Externí odkaz:
https://doaj.org/article/14328b9a03ed4d13b0d1dc8260b2cacb
Autor:
Federica Liotti, Maria Marotta, Daniela Sorriento, Chiara Pagliuca, Valeria Caturano, Giuseppe Mantova, Elena Scaglione, Paola Salvatore, Rosa Marina Melillo, Nella Prevete
Publikováno v:
Molecular Oncology, Vol 16, Iss 16, Pp 2959-2980 (2022)
Formyl peptide receptors (FPR1, FPR2 and FPR3) are innate immune sensors of pathogen and commensal bacteria and have a role in colonic mucosa homeostasis. We identified FPR1 as a tumour suppressor in gastric cancer cells due to its ability to sustain
Externí odkaz:
https://doaj.org/article/8d233d1b7aba45549cc81e3575cd683a
Autor:
Francesco Morra, Francesco Merolla, Giovanna Damia, Francesca Ricci, Silvia Varricchio, Gennaro Ilardi, Laura Arenare, Daniela Califano, Virginia Napolitano, Robert Fruscio, Rosa Marina Melillo, Luca Palazzo, Angela Celetti
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-21 (2022)
Abstract Background Treatment with PARP inhibitors (PARPi) is primarily effective against high-grade serous ovarian cancers (HGSOC) with BRCA1/2 mutations or other deficiencies in homologous recombination (HR) repair mechanisms. However, resistance t
Externí odkaz:
https://doaj.org/article/adbdda7216ee4ee5a177948cec916279
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/f7829a2bc4334292a8c855433da9caa0
Autor:
Federica Liotti, Narender Kumar, Nella Prevete, Maria Marotta, Daniela Sorriento, Caterina Ieranò, Andrea Ronchi, Federica Zito Marino, Sonia Moretti, Renato Colella, Efiso Puxeddu, Simona Paladino, Yoshihito Kano, Michael Ohh, Stefania Scala, Rosa Marina Melillo
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-16 (2021)
Abstract Background The programmed cell death-1 (PD-1) receptor and its ligands PD-L1 and PD-L2 are immune checkpoints that suppress anti-cancer immunity. Typically, cancer cells express the PD-Ls that bind PD-1 on immune cells, inhibiting their acti
Externí odkaz:
https://doaj.org/article/2f4f62c217e14f8f9af474f8e752ef34
Autor:
Nicola Normanno, Fabiana Tatangelo, Piera Maiolino, Stefania Scala, Caterina Ieranò, Dario Righelli, Crescenzo D'Alterio, Maria Napolitano, Luigi Portella, Giuseppina Rea, Federica Auletta, Sara Santagata, Anna Maria Trotta, Giuseppe Guardascione, Federica Liotti, Nella Prevete, Antonio Luciano, Antonio Barbieri, Annabella Di Mauro, Cristin Roma, Riziero Esposito Abate, Roberto Pacelli, Rosa Marina Melillo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 3 (2022)
Background Colorectal cancer (CRC) is one of the most prevalent and deadly tumors worldwide. The majority of CRC is resistant to anti-programmed cell death-1 (PD-1)-based cancer immunotherapy, with approximately 15% with high-microsatellite instabili
Externí odkaz:
https://doaj.org/article/b1c66c6327b04eacbccc9f2e0878a6d9
Publikováno v:
F1000Research, Vol 8 (2019)
Tumors modulate the host immune cells within their microenvironment to avoid recognition and elimination by our immune system, a phenotype called cancer immune escape. Different mechanisms responsible for cancer immune escape that result either in de
Externí odkaz:
https://doaj.org/article/6590a875d03b4a7883925527949b5e98
Autor:
Nella Prevete, Federica Liotti, Anna Illiano, Angela Amoresano, Piero Pucci, Amato de Paulis, Rosa Marina Melillo
Publikováno v:
OncoImmunology, Vol 6, Iss 4 (2017)
Chronic inflammation can result from inadequate engagement of resolution mechanisms, mainly accomplished by specialized pro-resolving mediators (SPMs) arising from the metabolic activity of lipoxygenases (ALOX5/15) on ω-6 or ω-3 essential polyunsat
Externí odkaz:
https://doaj.org/article/3e9f468db8c841eebeee7e1a406dbbd0
Autor:
Rosa Marina Melillo, Renato Franco, GnanaPrakasam Krishnamoorthy, Maria Svelto, Federica Liotti, Carla Visciano, Valentina Guarino, Elvira Avilla
Supplementary Figure 1 from Activation of TYRO3/AXL Tyrosine Kinase Receptors in Thyroid Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171cffbbbad9443b895fda863b3629d0
https://doi.org/10.1158/0008-5472.22389570.v1
https://doi.org/10.1158/0008-5472.22389570.v1
