Výsledky vyhledávání - "Rosa Maria Moresco 1"

Disruption of redox homeostasis for combinatorial drug efficacy in K-Ras tumors as revealed by metabolic connectivity profiling

Publikováno v: Cancer & Metabolism, Vol 8, Iss 1, Pp 1-15 (2020)
Cancer & metabolism 8 (2020): 22. doi:10.1186/s40170-020-00227-4
info:cnr-pdr/source/autori:Daniela Gaglio 1,2, Marcella Bonanomi 2,3, Silvia Valtorta 1,2,4, Rohit Bharat 23, Marilena Ripamonti 1,2, Federica Conte 2,5, Giulia Fiscon 2,5, Nicole Righi 2,3, Elisabetta Napodano 1,2, Federico Papa 2,5, Isabella Raccagni 1,2,6, Seth J Parker 7,8, Ingrid Cifola 9, Tania Camboni 9, Paola Paci 2,5,10, Anna Maria Colangelo 2,3, Marco Vanoni 2,3, Christian M Metallo 7,8, Rosa Maria Moresco 1,2,4, Lilia Alberghina 2,3/titolo:Disruption of redox homeostasis for combinatorial drug efficacy in K-Ras tumors as revealed by metabolic connectivity profiling/doi:10.1186%2Fs40170-020-00227-4/rivista:Cancer & metabolism/anno:2020/pagina_da:22/pagina_a:/intervallo_pagine:22/volume:8
Cancer & Metabolism

Abstract Background Rewiring of metabolism induced by oncogenic K-Ras in cancer cells involves both glucose and glutamine utilization sustaining enhanced, unrestricted growth. The development of effective anti-cancer treatments targeting metabolism m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::950f4c1a96c7b0580200136e0d3aea0e
http://link.springer.com/article/10.1186/s40170-020-00227-4

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Translation Imaging in Parkinson’s Disease: Focus on Neuroinflammation

Autor: Sara Belloli 1, 2, Michele Morari 3, Valentina Murtaj 2, 4, Silvia Valtorta 1, 5, Rosa Maria Moresco 1, Maria Carla Gilardi 1

Publikováno v: Frontiers in aging neuroscience 12 (2020): 152. doi:10.3389/fnagi.2020.00152
info:cnr-pdr/source/autori:Sara Belloli 1,2, Michele Morari 3, Valentina Murtaj 2,4, Silvia Valtorta 1,2,5, Rosa Maria Moresco 1,2,5 and Maria Carla Gilardi 1,5/titolo:Translation Imaging in Parkinson's Disease: Focus on Neuroinflammation/doi:10.3389%2Ffnagi.2020.00152/rivista:Frontiers in aging neuroscience/anno:2020/pagina_da:152/pagina_a:/intervallo_pagine:152/volume:12
Frontiers in Aging Neuroscience, Vol 12 (2020)
Frontiers in Aging Neuroscience

Parkinson's disease (PD) is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) and the appearance of α-synuclein insoluble aggregates known as Lewy bodies. Neurodegeneration is accompanied by neuroinflamma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7149142c9831865655a3b5262309e468

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Radiosynthesis and Preclinical Evaluation of 11C-VA426, a Cyclooxygenase-2 Selective Ligand

Autor: Assunta Carpinelli 1, 2, Paolo Rainone 2, 3 Sara Belloli 1, Annalisa Reale 4, Andrea Cappelli 4, Giuliani Germano 4, Valentina Murtaj 1, 5, Angela Coliva 2 Giuseppe Di Grigoli 1, Angela Valeri 4, Maria Carla Gilardi 1, Luigi Gianolli 2, Maurizio Anzini 4, Rosa Maria Moresco 1, 6

Publikováno v: Contrast media & molecular imaging 2019 (2019): 5823261–13. doi:10.1155/2019/5823261.
info:cnr-pdr/source/autori:Assunta Carpinelli 1,2, Paolo Rainone 2,3 Sara Belloli 1,2, Annalisa Reale 4, Andrea Cappelli 4, Giuliani Germano 4, Valentina Murtaj 1,2,5, Angela Coliva 2 Giuseppe Di Grigoli 1,2, Angela Valeri 4, Maria Carla Gilardi 1, Luigi Gianolli 2, Maurizio Anzini 4 and Rosa Maria Moresco 1,2,6/titolo:Radiosynthesis and Preclinical Evaluation of 11C-VA426, a Cyclooxygenase-2 Selective Ligand/doi:10.1155%2F2019%2F5823261./rivista:Contrast media & molecular imaging/anno:2019/pagina_da:5823261/pagina_a:13/intervallo_pagine:5823261–13/volume:2019

Cyclooxygenase-2 (COX-2) is involved in the inflammatory response, and its recurrent overexpression in cancers as well as in neurodegenerative disorders has made it an important target for therapy. For this reason, noninvasive imaging of COX-2 expres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::a2e10f6605c074fd7829dfd4b1a5ca70
http://www.cnr.it/prodotto/i/407685

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18F-VC701-PET and MRI in the in vivo neuroinflammation assessment of a mouse model of multiple sclerosis

Autor: Sara Belloli 1, 2, 3, Lucia Zanotti 4, Valentina Murtaj 2, 5, 6, Cristina Mazzon 7, 8, Giuseppe Di Grigoli 1, Cristina Monterisi 6, Valeria Masiello 6, Leonardo Iaccarino 9, Andrea Cappelli 10, Pietro Luigi Poliani 11, Letterio Salvatore Politi 2, Rosa Maria Moresco 1

Publikováno v: Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-11 (2018)
Journal of neuroinflammation 15 (2018): 33. doi:10.1186/s12974-017-1044-x
info:cnr-pdr/source/autori:Sara Belloli 1,2,3, Lucia Zanotti 4, Valentina Murtaj 2,5,6, Cristina Mazzon 7,8, Giuseppe Di Grigoli 1,2, Cristina Monterisi 6, Valeria Masiello 6, Leonardo Iaccarino 9, Andrea Cappelli 10, Pietro Luigi Poliani 11, Letterio Salvatore Politi 2,12,13* and Rosa Maria Moresco 1,2,6*/titolo:18F-VC701-PET and MRI in the in vivo neuroinflammation assessment of a mouse model of multiple sclerosis./doi:10.1186%2Fs12974-017-1044-x/rivista:Journal of neuroinflammation/anno:2018/pagina_da:33/pagina_a:/intervallo_pagine:33/volume:15

Background Positron emission tomography (PET) using translocator protein (TSPO) ligands has been used to detect neuroinflammatory processes in neurological disorders, including multiple sclerosis (MS). The aim of this study was to evaluate neuroinfla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aade732de1a19528fc8a4752b06da04
http://hdl.handle.net/11379/502008

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Metformin and Temozolomide, a synergic option to overcome resistance in glioblastoma multiforme models

Publikováno v: Oncotarget (2017).
info:cnr-pdr/source/autori:Silvia Valtorta 1,2,3,4,*, Alessia Lo Dico 5,*, Isabella Raccagni 1,2,3,4, Daniela Gaglio 2,4, Sara Belloli 2,3,4, Letterio S. Politi 6,7,8, Cristina Martelli 5, Cecilia Diceglie 5,1, Marcella Bonanomi 4, Giulia Ercoli 9, Valentina Vaira 5,9, Luisa Ottobrini 2,5,* and Rosa Maria Moresco 1,2,3,4,*/titolo:Metformin and Temozolomide, a synergic option to overcome resistance in glioblastoma multiforme models/doi:/rivista:Oncotarget/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume

Glioblastoma multiforme (GBM) is the most aggressive primary brain tumor with poor survival. Cytoreduction in association with radiotherapy and temozolomide (TMZ) is the standard therapy, but response is heterogeneous and life expectancy is limited.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::7ffbe54f58bfb27b307ca2d8e493dcce
https://publications.cnr.it/doc/379984

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