Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Rosa Maria Karl"'
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Akademický článek
Two types of functionally distinct Ca2+ stores in hippocampal neurons
Autor: Hsing-Jung Chen-Engerer, Jana Hartmann, Rosa Maria Karl, Jun Yang, Stefan Feske, Arthur Konnerth
Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
It is generally assumed, from previous studies in cerebellar Purkinje neurons, that IP3 and Ry receptors share the same intracellular Ca2+ pool. In this study, the authors demonstrate the existence of two functionally distinct Ca2+ stores in mouse CA
Externí odkaz: https://doaj.org/article/b6b7c12a9b294ae6afc7fbfb980b4c83
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2
Two types of functionally distinct Ca2+ stores in hippocampal neurons
Autor: Arthur Konnerth, Jun Yang, Stefan Feske, Jana Hartmann, Rosa Maria Karl, Hsing-Jung Chen-Engerer
Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Nature Communications
It is widely assumed that inositol trisphosphate (IP3) and ryanodine (Ry) receptors share the same Ca2+ pool in central mammalian neurons. We now demonstrate that in hippocampal CA1 pyramidal neurons IP3- and Ry-receptors are associated with two func
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9808edbe620f227f947f8833c818c46f
http://link.springer.com/article/10.1038/s41467-019-11207-8
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3
Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity
Autor: Wolfgang Wurst, Ingrid Wagner, Thomas Misgeld, Rosa Maria Karl, Ralf Kühn, Jennifer Wettmarshausen, Nicolas Snaidero, Stefan F. Lichtenthaler, Laura Trovò, Stephan A. Müller, Fabiana Perocchi, Doron Merkler, Caroline Fecher, Jana Hartmann, Arthur Konnerth, Sylvia Heink, Thomas Korn, Oskar Ortiz
Publikováno v: Nature Neuroscience
Nature reviews / Neuroscience 22(10), 1731-1742 (2019). doi:10.1038/s41593-019-0479-z
Nature Neuroscience, Vol. 22, No 10 (2019) pp. 1731-1742
Mitochondria vary in morphology and function in different tissues; however, little is known about their molecular diversity among cell types. Here we engineered MitoTag mice, which express a Cre recombinase-dependent green fluorescent protein targete
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c650d2db0b8796ebba9490815ff77185
https://pubmed.ncbi.nlm.nih.gov/31554939
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5
STIM1 Controls Neuronal Ca2+ Signaling, mGluR1-Dependent Synaptic Transmission, and Cerebellar Motor Behavior
Autor: Thomas Misgeld, Ryan P.D. Alexander, Yoshihiro Baba, Charlotta Rühlmann, Arthur Konnerth, Anna Ansel, Helmuth Adelsberger, Tomohiro Kurosaki, Jana Hartmann, Rosa Maria Karl, Monika S. Brill, Kenji Sakimura
Publikováno v: Neuron. 82:635-644
In central mammalian neurons, activation of metabotropic glutamate receptor type1 (mGluR1) evokes a complex synaptic response consisting of IP3 receptor-dependent Ca(2+) release from internal Ca(2+) stores and a slow depolarizing potential involving
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e11a1f450f29bf6b43d8b014450452d8
https://doi.org/10.1016/j.neuron.2014.03.027
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An assay to image neuronal microtubule dynamics in mice
Autor: Martin Kerschensteiner, Jochen Herms, Emily E. Weigand, Tatjana Kleele, Arthur Konnerth, Sina Stern, Thomas Misgeld, Ronald Naumann, Leanne Godinho, Rosa Maria Karl, Philip R. Williams, Derron L. Bishop, Frank Bradke, Petar Marinković, Peter Engerer, Jana Hartmann
Publikováno v: Nature Communications
Nature Communications 5(1), 4827 (2014). doi:10.1038/ncomms5827
Microtubule dynamics in neurons play critical roles in physiology, injury and disease and determine microtubule orientation, the cell biological correlate of neurite polarization. Several microtubule binding proteins, including end-binding protein 3
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::117edd01ebdc277d35e5a5370f0ee58e
https://pubmed.ncbi.nlm.nih.gov/25219969
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The 1,1- dianisyl-2,2,2-trichloroethyl group as 2′-hydroxyl protection of ribonucleotides
Autor: Roland Klösel, Stephan König, Rosa Maria Karl, S. Lehnhoff
Publikováno v: Tetrahedron. 52:1493-1502
The 1,1-dianisyl-2,2,2-trichloroethyl group (DATE, 1) was introduced as a new 2′-hydroxyl protecting group of ribonucleotides. The usefulness of DATE as a 2′-OH protection was demonstrated in the solid phase synthesis of a dinucleotide by the pho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9d6730ca85d7887d386a9cc18d5209df
https://doi.org/10.1016/0040-4020(95)00981-7
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The 1,1-Dianisyl-2,2,2-trichloroethyl Moiety as a New Protective Group for the Synthesis of Dinucleostde Trifluoromethylphosphonates
Autor: Michael Mayer, Wolfgang Richter, Roland Klösel, Rosa Maria Karl, Ivar Ugi
Publikováno v: Nucleosides and Nucleotides. 15:379-386
The new 1,1-Dianisyl-2,2,2-trichloroethyl moiety (DATE) is used as an acid and base stable protective group for nucleosides. 5′-O-DATE-thymidine and 3′-O-acetyl-thymidine are phosphorylated with CF3P(NR2)2 to the corresponding thymidine trifluoro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c7968e8dc1509a0271f99df13c379968
https://doi.org/10.1080/07328319608002391
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