Two types of functionally distinct Ca2+ stores in hippocampal neurons

Autor: Hsing-Jung Chen-Engerer, Jana Hartmann, Rosa Maria Karl, Jun Yang, Stefan Feske, Arthur Konnerth

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)

It is generally assumed, from previous studies in cerebellar Purkinje neurons, that IP3 and Ry receptors share the same intracellular Ca2+ pool. In this study, the authors demonstrate the existence of two functionally distinct Ca2+ stores in mouse CA

Externí odkaz: https://doaj.org/article/b6b7c12a9b294ae6afc7fbfb980b4c83

Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity

Autor: Wolfgang Wurst, Ingrid Wagner, Thomas Misgeld, Rosa Maria Karl, Ralf Kühn, Jennifer Wettmarshausen, Nicolas Snaidero, Stefan F. Lichtenthaler, Laura Trovò, Stephan A. Müller, Fabiana Perocchi, Doron Merkler, Caroline Fecher, Jana Hartmann, Arthur Konnerth, Sylvia Heink, Thomas Korn, Oskar Ortiz

Publikováno v: Nature Neuroscience
Nature reviews / Neuroscience 22(10), 1731-1742 (2019). doi:10.1038/s41593-019-0479-z
Nature Neuroscience, Vol. 22, No 10 (2019) pp. 1731-1742

Mitochondria vary in morphology and function in different tissues; however, little is known about their molecular diversity among cell types. Here we engineered MitoTag mice, which express a Cre recombinase-dependent green fluorescent protein targete

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c650d2db0b8796ebba9490815ff77185
https://pubmed.ncbi.nlm.nih.gov/31554939

STIM1 Controls Neuronal Ca2+ Signaling, mGluR1-Dependent Synaptic Transmission, and Cerebellar Motor Behavior

Autor: Thomas Misgeld, Ryan P.D. Alexander, Yoshihiro Baba, Charlotta Rühlmann, Arthur Konnerth, Anna Ansel, Helmuth Adelsberger, Tomohiro Kurosaki, Jana Hartmann, Rosa Maria Karl, Monika S. Brill, Kenji Sakimura

Publikováno v: Neuron. 82:635-644

In central mammalian neurons, activation of metabotropic glutamate receptor type1 (mGluR1) evokes a complex synaptic response consisting of IP3 receptor-dependent Ca(2+) release from internal Ca(2+) stores and a slow depolarizing potential involving

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e11a1f450f29bf6b43d8b014450452d8
https://doi.org/10.1016/j.neuron.2014.03.027

The 1,1- dianisyl-2,2,2-trichloroethyl group as 2′-hydroxyl protection of ribonucleotides

Autor: Roland Klösel, Stephan König, Rosa Maria Karl, S. Lehnhoff

Publikováno v: Tetrahedron. 52:1493-1502

The 1,1-dianisyl-2,2,2-trichloroethyl group (DATE, 1) was introduced as a new 2′-hydroxyl protecting group of ribonucleotides. The usefulness of DATE as a 2′-OH protection was demonstrated in the solid phase synthesis of a dinucleotide by the pho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9d6730ca85d7887d386a9cc18d5209df
https://doi.org/10.1016/0040-4020(95)00981-7

Stereoselective Syntheses of Peptide Derivatives with 2‐Acetamido‐3,4,6‐tri‐ O ‐acetyl‐1‐amino‐2‐deoxy‐β‐ D ‐glucopyranose by Four‐Component Condensation

Autor: Stefan Lehnhoff, Ivar Ugi, Rosa Maria Karl, Matthias Goebel, Roland Klösel

Publikováno v: Angewandte Chemie International Edition in English. 34:1104-1107

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::abccca6ad1a7d9f89d5a92522163080d
https://doi.org/10.1002/anie.199511041