Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rosa María Chávez-Santos"'
Autor:
Carolina Castañeda-Fernandez, Rosa María Chávez-Santos, Mayra Silva-Miranda, Clara Espitia-Pinzón, Roberto Martínez, Anna Kozina
Publikováno v:
International journal of pharmaceutics. 622
Rifampicin is one of the most commonly used antibiotics for treating tuberculosis, but shows low bioavailability and requires long-term administration, and hence its use may result in severe side effects. Encapsulation of rifampicin in polymeric rese
Autor:
Rosa María Chávez-Santos, Clara Espitia, Luis Chacón-García, Mayra Silva Miranda, Abel Suárez-Castro, Gustavo Pretelin-Castillo, Rodrigo Aguayo-Ortiz, Roberto Martinez
Publikováno v:
Infection and Drug Resistance
Background Tuberculosis is an infectious disease caused by the bacillus Mycobacterium tuberculosis. Compounds including a sulfur-containing scaffold have been shown to be key scaffolds in various antituberculosis agents. Interestingly, the 3-hydroxy-
Autor:
María Teresa Ramírez-Apan, Paul E. Reyes-Gutiérrez, Roberto Martinez, Rosa María Chávez-Santos, Rubén O. Torres-Ochoa
Publikováno v:
CHEMICAL & PHARMACEUTICAL BULLETIN. 65:973-981
In this study, the pyrrolo[2,1-a]isoquinolines 4a-n were synthesized in good yields in a three steps synthesis from the corresponding α,β-unsaturated esters starting materials. These compounds were tested on six human cancer cells lines to measure
Autor:
Rosa María Chávez-Santos, Roberto Martinez, Clara Inés Espitia-Pinzón, Rogelio Pedraza-Rodríguez, Gustavo Pretelin-Castillo, Ángela M Hernández-Báez, Aldahir Ramos-Orea, Mayra Silva Miranda, Sandra Cotlame-Pérez
Publikováno v:
Drug development researchREFERENCES. 81(3)
Acylthiosemicarbazides 8a-n were designed by structural modification of lead Compound 7. The syntheses of 8a-n involve a five-step procedure starting from carboxylic acids. Compounds 8a-n were tested against three Mycobacterium tuberculosis strains t
Autor:
Rosa María, Chávez-Santos, Paul Eduardo, Reyes-Gutiérrez, Rubén Omar, Torres-Ochoa, María Teresa, Ramírez-Apan, Roberto, Martínez
Publikováno v:
Chemicalpharmaceutical bulletin. 65(10)
In this study, the pyrrolo[2,1-a]isoquinolines 4a-n were synthesized in good yields in a three steps synthesis from the corresponding α,β-unsaturated esters starting materials. These compounds were tested on six human cancer cells lines to measure