Výsledky vyhledávání - "Rosa M. Dalton"

Increased amounts of the influenza virus nucleoprotein do not promote higher levels of viral genome replication

Autor: Anne E. Mullin, Rosa M. Dalton, Paul Digard, Maria João Amorim, Debra Elton

Publikováno v: Journal of General Virology. 85:3689-3698

Influenza virus genome replication requires the virus-encoded nucleoprotein (NP), partly because it is necessary to encapsidate the viral genomic RNA (vRNA) and antigenomic cRNA segments into ribonucleoproteins (RNPs). However, there is also evidence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d604c07f055a804989e9cc4726ac242
https://doi.org/10.1099/vir.0.80518-0

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Astrovirus acute gastroenteritis among children in Madrid, Spain

Autor: Enriqueta Roman, Alicia Sánchez-Fauquier, Roger I. Glass, Ana A. Negredo, Isabel Wilhelmi, Rosa M. Dalton

Publikováno v: The Pediatric Infectious Disease Journal. 21:1038-1041

Human astroviruses cause infantile gastroenteritis worldwide, but the prevalence of disease varies greatly by setting. Since 1997 we have conducted a survey to determine the causes of diarrhea among Spanish children attending an emergency room in Mad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98a228ee5dbe6976e53a80003b2984ec
https://doi.org/10.1097/00006454-200211000-00012

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Rescue of Infectious Birnavirus from Recombinant Ribonucleoprotein Complexes

Autor: José F. Rodríguez, Rosa M. Dalton

Publikováno v: PLoS ONE
PLoS ONE, Vol 9, Iss 1, p e87790 (2014)

Birnaviruses are unconventional members of the icosahedral double-stranded (dsRNA) RNA virus group. The main differential birnavirus trait is the lack of the inner icosahedral transcriptional core, a ubiquitous structure conserved in all other icosah

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dafeda1f8f9e83849745648b878b5994
http://europepmc.org/articles/PMC3907549

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An overlapping protein-coding region in influenza A virus segment 3 modulates the host response

Autor: Rosa M. Dalton, Louis M. Schwartzman, Andrew E. Firth, Amy C. Y. Lo, Jeffery K. Taubenberger, Yongli Xiao, Rebecca L. Dunfee, Norma M. Wills, John C. Kash, Adrian Ozinsky, John F. Atkins, Brett W. Jagger, Stacey Efstathiou, G. L. Bell, Paul Digard, Kathie-Anne Walters, Helen M. Wise

Publikováno v: Jagger, B W, Wise, H M, Kash, J C, Walters, K A, Wills, N M, Xiao, Y L, Dunfee, R L, Schwartzman, L M, Ozinsky, A, Bell, G L, Dalton, R M, Lo, A, Efstathiou, S, Atkins, J F, Firth, A E, Taubenberger, J K & Digard, P 2012, ' An Overlapping Protein-Coding Region in Influenza A Virus Segment 3 Modulates the Host Response ', Science, vol. 337, no. 6091, pp. 199-204 . https://doi.org/10.1126/science.1222213

Influenza's Cryptic Constraint Because of the well-known pandemic potential of influenza viruses, it is important to understand the range of molecular interactions between the virus and its host. Despite years of intensive research on the virus, Jagg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e17e6e153ecd6f5b7453ec3a2b0edd3
https://pubmed.ncbi.nlm.nih.gov/22798590

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Overlapping signals for translational regulation and packaging of influenza A virus segment 2

Autor: Paul Digard, Julia R. Gog, Brett W. Jagger, Helen M. Wise, Jeffery Taubenberger, Martin D. Curran, Cyril Barbezange, Rosa M. Dalton, Emma C. Anderson

Publikováno v: Wise, H M, Barbezange, C, Jagger, B W, Dalton, R M, Gog, J R, Curran, M D, Taubenberger, J K, Anderson, E C & Digard, P 2011, ' Overlapping signals for translational regulation and packaging of influenza A virus segment 2 ', Nucleic Acids Research, vol. 39, no. 17, pp. 7775-7790 . https://doi.org/10.1093/nar/gkr487
Nucleic Acids Research

Influenza A virus segment 2 mRNA expresses three\ud polypeptides: PB1, PB1-F2 and PB1-N40, from AUGs\ud 1, 4 and 5 respectively. Two short open reading\ud frames (sORFs) initiated by AUGs 2 and 3 are also\ud present. To understand translational regul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9812c0bd6e19532665e865eba7ca251
https://hdl.handle.net/20.500.11820/f8763ad7-c0ad-4fa8-8019-fdf487a9041a

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Nuclear export of influenza A virus mRNAs requires ongoing RNA polymerase II activity

Autor: Liz Medcalf, Eliot Read, Paul Digard, Rosa M. Dalton, Maria-Joao Amorim

Publikováno v: Traffic (Copenhagen, Denmark). 8(1)

Influenza A virus transcribes its segmented negative sense RNA genome in the nuclei of infected cells in a process long known to require host RNA polymerase II (RNAP-II). RNA polymerase II synthesizes pre-mRNAs whose 5'-cap structures are scavenged b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::868e5416c0f8bf15d96e9e670d3826f2
https://pubmed.ncbi.nlm.nih.gov/17132145

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Temperature sensitive influenza A virus genome replication results from low thermal stability of polymerase-cRNA complexes

Autor: Rosa M. Dalton, Maria João Amorim, Paul Digard, Anne E. Mullin, Laurence Tiley, Elizabeth Medcalf

Publikováno v: Dalton, R M, Mullin, A E, Amorim, M J, Medcalf, L, Tiley, L S & Digard, P 2006, ' Temperature sensitive influenza A virus genome replication results from low thermal stability of polymerase-cRNA complexes ', Virology Journal, vol. 3, no. 58 . https://doi.org/10.1186/1743-422X-3-58
Virology Journal, Vol 3, Iss 1, p 58 (2006)
Virology Journal

Background The RNA-dependent RNA polymerase of Influenza A virus is a determinant of viral pathogenicity and host range that is responsible for transcribing and replicating the negative sense segmented viral genome (vRNA). Transcription produces capp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5544409a1dc0d4449ec6428db39395da
https://www.pure.ed.ac.uk/ws/files/11478939/Temperature_sensitive_influenza_A_virus_genome_replication_results_from_low_thermal_stability_of_polymerase_cRNA_complexes.pdf

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Vaccinia virus recombinant expressing an 87-kilodalton polyprotein that is sufficient to form astrovirus-like particles

Autor: Esperanza Pérez Pastrana, Rosa M. Dalton, Alicia Sánchez-Fauquier

Publikováno v: Journal of virology. 77(16)

Human astrovirus is an important cause of acute gastroenteritis. We have generated, for the first time, a vaccinia virus recombinant expressing the astrovirus 87-kDa structural polyprotein. The results demonstrate that this expression results in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e7f12aa1e00203d32c6fb66d6278da2
https://pubmed.ncbi.nlm.nih.gov/12885927

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Molecular detection of human calicivirus among Spanish children with acute gastroenteritis

Autor: Ana Isabel Negredo, Rosa M. Dalton, Isabel Wilhelmi, Enriqueta Roman, Alicia Sánchez-Fauquier

Publikováno v: Journal of clinical microbiology. 40(10)

A survey was conducted among Spanish children with gastroenteritis treated in an emergency room. Reverse transcription-PCR with specimens negative for other enteric pathogens was used. The minimum incidence of human calicivirus infection was 7.7%, wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f12a1325da249799f7021d2dde4517d
https://pubmed.ncbi.nlm.nih.gov/12354900

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