Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Rosa M. Canet-Avilés"'
Autor:
William Z. Potter, Alzheimer’s Disease Neuroimaging Initiative, Laetitia Cortes, Mark H. Watson, Daniel Chelsky, Susan Baker, Nandini Raghavan, Daniel S. Spellman, Kelly L. Umaña, Clifford R. Jack, Ondrej Libiger, Rosa M. Canet‐Avilés, Michael C. Biarnes, Yannick-André Breton, Leslie M. Shaw, Angus C. Nairn
Publikováno v:
Alzheimers Dement
Introduction Biomarkers that reflect pathologic processes affecting neuronal function during preclinical and early stages of Alzheimer's disease (AD) are needed to aid drug development. Methods A targeted, stable isotope, quantitative mass spectromet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d11592cef2afb777517e0bc5355fbea6
https://europepmc.org/articles/PMC9222372/
https://europepmc.org/articles/PMC9222372/
Autor:
Leslie M. Shaw, Rosa M. Canet‐Avilés, Daniel Chelsky, Angus C. Nairn, Clifford R. Jack, Daniel S Spellman, Nandini Raghavan, Yannick-André Breton, William Z. Potter, Laetitia Cortes, Ondrej Libiger, Mark H. Watson, Susan Baker, Kelly L. Umaña
Publikováno v:
Alzheimer's & Dementia. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5de6d6a2bde87bfed51678be2bcb2d7f
https://doi.org/10.1002/alz.047605
https://doi.org/10.1002/alz.047605
Autor:
Georgia Taylor, Hye-Mee Na, Rosa M. Canet-Avilés, Ron R. Kopito, Ranjita Betarbet, Gary R. Klinefelter, Takao Yagi, Akemi Yagi, Serena Lund, Mark R. Cookson, Chris McLendon, Pier G. Mastroberardino, Neil F. Bence, Todd B. Sherer, Byoung Boo Seo, Jin Ho Kim, J. Timothy Greenamyre
Publikováno v:
Neurobiology of Disease, Vol 22, Iss 2, Pp 404-420 (2006)
Sporadic Parkinson's disease (PD) is most likely caused by a combination of environmental exposures and genetic susceptibilities, although there are rare monogenic forms of the disease. Mitochondrial impairment at complex I, oxidative stress, alpha-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d4d614211d8938dfc5ca070496dd878
http://www.sciencedirect.com/science/article/pii/S0969996105003372
http://www.sciencedirect.com/science/article/pii/S0969996105003372
Autor:
Rosa M. Canet-Avilés, Mona Kaleem, Marcel P. van der Brug, David Miller, Stephen Hague, Rili Ahmad, Jeff Blackinton, Mark R. Cookson
Publikováno v:
Molecular Brain Research. 134:76-83
Mutations in the DJ-1 gene are associated with recessive, early onset Parkinson's disease (PD). We reported previously that one of the point mutations, L166P, destabilizes the protein and thus produces an effective knockout of the gene. Here, we have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bbab168ba679d644185460379d38559
https://doi.org/10.1016/j.molbrainres.2004.09.004
https://doi.org/10.1016/j.molbrainres.2004.09.004
Autor:
Rili Ahmad, Stephen Hague, Gary R. Klinefelter, Chris McLendon, Jayanth Chandran, Mark R. Cookson, Julia Stadler, Rosa M. Canet-Avilés, David Miller, Melisa J. Baptista, Donald M. Carter, Peng-Peng Zhu, Craig Blackstone
Publikováno v:
Journal of Biological Chemistry. 278:36588-36595
Mutations in a gene on chromosome 1, DJ-1, have been reported recently to be associated with recessive, earlyonset Parkinson's disease. While one mutation is a large deletion that is predicted to produce an effective knockout of the gene, the second
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e89de256c93711b070bd9e66b0e8c8
https://doi.org/10.1074/jbc.m304272200
https://doi.org/10.1074/jbc.m304272200
Autor:
Rili Ahmad, Dagmar Ringe, Mark R. Cookson, Mark A. Wilson, Melisa J. Baptista, Gregory A. Petsko, Sourav Bandyopadhyay, David Miller, Chris McLendon, Rosa M. Canet-Avilés
Loss-of-function DJ-1 mutations can cause early-onset Parkinson's disease. The function of DJ-1 is unknown, but an acidic isoform accumulates after oxidative stress, leading to the suggestion that DJ-1 is protective under these conditions. We address
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b673caf5e91202463d977f9d6c3ae2
https://europepmc.org/articles/PMC428480/
https://europepmc.org/articles/PMC428480/
Autor:
Rohan de Silva, Hiroyashi Ariga, Ann E. Kingsbury, Andrew J. Lees, Andrew D. Hope, A.J. Leonard, John Hardy, Patrick M. Abou-Sleiman, Alan M. Pittman, Nicholas W. Wood, Mark R. Cookson, Tamas Revesz, Rina Bandopadhyay, Ian M. Evans, C Strand, Rosa M. Canet-Avilés, Andrew R. Reid, Daniel G. Healy, Tammaryn Lashley, Chris McLendon, David Miller
Publikováno v:
Brain : a journal of neurology. 127(Pt 2)
Two mutations in the DJ-1 gene on chromosome1p36 have been identified recently to cause early-onset, autosomal recessive Parkinson's disease. As no information is available regarding the distribution of DJ-1 protein in the human brain, in this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fed98606c68437ad854722d95b476be
https://pubmed.ncbi.nlm.nih.gov/14662519
https://pubmed.ncbi.nlm.nih.gov/14662519
Autor:
Ranjita Betarbet, Rosa M. Canet-Aviles, Todd B. Sherer, Pier G. Mastroberardino, Chris McLendon, Jin-Ho Kim, Serena Lund, Hye-Mee Na, Georgia Taylor, Neil F. Bence, Ron Kopito, Byoung Boo Seo, Takao Yagi, Akemi Yagi, Gary Klinefelter, Mark R. Cookson, J. Timothy Greenamyre
Publikováno v:
Neurobiology of Disease, Vol 22, Iss 2, Pp 404-420 (2006)
Sporadic Parkinson's disease (PD) is most likely caused by a combination of environmental exposures and genetic susceptibilities, although there are rare monogenic forms of the disease. Mitochondrial impairment at complex I, oxidative stress, α-synu
Externí odkaz:
https://doaj.org/article/81619bfee22e4082851ee792eae91a25