Frequency and Clinicopathological Profile Associated with Braf Mutations in Patients with Advanced Melanoma in Spain

Autor: Jose A. Lopez-Martin, Ana Arance Fernández, Juan José Ríos-Martín, Javier Hernández-Losa, Lucía Alós Hernández, Pablo Cerezuela Fuentes, Sebastián Ortiz Reina, Eugenia Ortega Izquierdo, Rosa M Martí, Jesús Soberino García, Berta Ferrer Fábrega, José Luis Rodríguez Peralto

Publikováno v: Translational Oncology, Vol 13, Iss 6, Pp - (2020)

Real-world data on BRAF mutation frequency in advanced melanoma are lacking in Spain. Moreover, data available on clinicopathological profile of patients with advanced BRAF-mutant melanoma are currently limited. This study aimed to assess the frequen

Externí odkaz: https://doaj.org/article/3bbb0562665e42b2b68b69248b9620e6

Descriptive study of naevus involution in a series of 74 patients with atypical naevus syndrome under SIAscopy digital follow‐up

Autor: Sara Moreno, S. Gatius, Josefa Barrera, Carla Barceló, Xavier Matias-Guiu, X. Soria, Rosa M. Martí, Alvar Vea, Oscar Maiques, M. Santacana

Publikováno v: Journal of the European Academy of Dermatology and Venereology. 34:1210-1217

BACKGROUND Characterization of nevi involution could help to understand the biological behaviour of melanocytic neoplasms. OBJECTIVE To describe the frequency and morphology of naevus involution in a series of patients with atypical naevus syndrome u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b1f4ad70a562e9bd274e65be64bac68
https://doi.org/10.1111/jdv.16084

LAP1 supports nuclear plasticity during constrained migration

Autor: Oscar Maiques, Marie-Charlotte Domart, Bruce Fanshawe, Rosa M. Martí, Lucy M. Collinson, Victoria Sanz-Moreno, Matt Renshaw, Irene Rodriguez-Hernandez, Jeremy G. Carlton, Xavier Matias-Guiu, Yaiza Jung-Garcia

Metastasis involves dissemination of cancer cells away from a primary tumour and colonisation at distal sites. During this process, cancer cells must negotiate multiple physical constraints imposed by the microenvironment and tissue structure. The bi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f3cc27d762b387d84ed29954698d2466
https://doi.org/10.1101/2021.06.23.449503

T-Type Calcium Channels: A Potential Novel Target in Melanoma

Autor: Carla Barceló, Oscar Maiques, Inés de la Rosa, Anna Macià, Rosa M. Martí, Pol Sisó

Publikováno v: Cancers
Cancers, Vol 12, Iss 2, p 391 (2020)
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio Abierto de la UdL
Universitad de Lleida
Recercat. Dipósit de la Recerca de Catalunya
instname

T-type calcium channels (TTCCs) are overexpressed in several cancers. In this review, we summarize the recent advances and new insights into TTCC biology, tumor progression, and prognosis biomarker and therapeutic potential in the melanoma field. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88dae66f1b1cde429e40b0dd5e402cbc
https://pubmed.ncbi.nlm.nih.gov/32046241

La señalización WNT11-FZD7-DAAM1 es compatible con las capacidades de iniciación de tumores y la invasión ameboide del melanoma

Autor: Joaquim Marcolval, Irene Rodriguez-Hernandez, Ilaria Malanchi, Gilbert O. Fruhwirth, Bruce Fanshawe, Leonie Kohlhammer, Rosa M. Martí, Oscar Maiques, R.M. Penín, Victoria L. Bridgeman, Joanne Monger, Xavier Matias-Guiu, Gaia Cantelli, Anna Perdrix-Rosell, Victoria Sanz-Moreno, Sophia N. Karagiannis, Jose L. Orgaz

Publikováno v: Biblos-e Archivo. Repositorio Institucional de la UAM
Consejo Superior de Investigaciones Científicas (CSIC)
Recercat. Dipósit de la Recerca de Catalunya
instname
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Biblos-e Archivo: Repositorio Institucional de la UAM
Universidad Autónoma de Madrid
Repositorio Abierto de la UdL
Universitad de Lleida
Rodriguez-Hernandez, I, Maiques, O, Kohlhammer, L, Cantelli, G, Perdrix-Rosell, A, Monger, J, Fanshawe, B, Bridgeman, V L, Karagiannis, S N, Penin, R M, Marcolval, J, Marti, R M, Matias-Guiu, X, Fruhwirth, G O, Orgaz, J L, Malanchi, I & Sanz-Moreno, V 2020, ' WNT11-FZD7-DAAM1 signalling supports tumour initiating abilities and melanoma amoeboid invasion ', Nature Communications, vol. 11, no. 1, 5315, pp. 5315 . https://doi.org/10.1038/s41467-020-18951-2
Digital.CSIC. Repositorio Institucional del CSIC
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Nature Communications

Melanoma is a highly aggressive tumour that can metastasize very early in disease progression. Notably, melanoma can disseminate using amoeboid invasive strategies. We show here that high Myosin II activity, high levels of ki-67 and high tumour-initi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30feb0aa6580ce44cc89db78d547e8ed
http://hdl.handle.net/10486/696040