Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Rosa Luisa Potenza"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1751 (2024)
Amyotrophic lateral sclerosis (ALS) is a rare progressive motor neuron disease that, due to its high complexity, still lacks effective treatments. Development of a new drug is a highly costly and time-consuming process, and the repositioning of appro
Externí odkaz:
https://doaj.org/article/f8555b44860549799661bfa58b2fa7d9
Autor:
Maria Puopolo, Cristina Morciano, Maria Buoncervello, Chiara De Nuccio, Rosa Luisa Potenza, Elena Toschi, Lucia Palmisano
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Background The 2019 novel coronavirus disease (COVID-19) pandemic has highlighted the importance of health research and fostered clinical research as never before. A huge number of clinical trials for potential COVID-19 interventions have be
Externí odkaz:
https://doaj.org/article/e2b8fee284f4431390dd9a97cd7093bd
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7426 (2022)
Recently, several chemotherapeutic drugs have been repositioned in neurological diseases, based on common biological backgrounds and the inverse comorbidity between cancer and neurodegenerative diseases. Fenretinide (all-trans-N-(4-hydroxyphenyl) ret
Externí odkaz:
https://doaj.org/article/d1fba85fb9d84835ac5ee5092d163148
Autor:
Valentina Chiodi, Motokazu Uchigashima, Sarah Beggiato, Antonella Ferrante, Monica Armida, Alberto Martire, Rosa Luisa Potenza, Luca Ferraro, Sergio Tanganelli, Masahiko Watanabe, Maria Rosaria Domenici, Patrizia Popoli
Publikováno v:
Neurobiology of Disease, Vol 45, Iss 3, Pp 983-991 (2012)
Cannabinoid CB1 receptors (CB1Rs) are known to be downregulated in patients and in animal models of Huntington's disease (HD). However, the functional meaning of this reduction, if any, is still unclear. Here, the effects of the cannabinoid receptor
Externí odkaz:
https://doaj.org/article/698433aac9624ddc9958c9a644848696
Autor:
Alberto Martire, Antonella Ferrante, Rosa Luisa Potenza, Monica Armida, Roberta Ferretti, Antonella Pézzola, Maria Rosaria Domenici, Patrizia Popoli
Publikováno v:
Neurobiology of Disease, Vol 37, Iss 1, Pp 99-105 (2010)
Excitotoxicity plays a major role in the pathogenesis of Huntington disease (HD), a fatal neurodegenerative disorder. Adenosine A2A receptors (A2ARs) modulate excitotoxicity and have been suggested to play a pathogenetic role in HD. The main aim of t
Externí odkaz:
https://doaj.org/article/29a15203e60540389caee6b147c92159
Autor:
Maria Puopolo, Cristina Morciano, Maria Buoncervello, Chiara De Nuccio, Rosa Luisa Potenza, Elena Toschi, Lucia Palmisano
Publikováno v:
Trials. 23(1)
Background The 2019 novel coronavirus disease (COVID-19) pandemic has highlighted the importance of health research and fostered clinical research as never before. A huge number of clinical trials for potential COVID-19 interventions have been launch
Autor:
Younis Baqi, Patrizia Popoli, Antonella Pèzzola, Rosa Luisa Potenza, Monica Armida, Alessandra Matteucci, Christa E. Müller
Publikováno v:
Neurochemical Research. 44:1037-1042
Amyotrophic lateral sclerosis (ALS) is a fatal progressing neurodegenerative disease; to date, despite the intense research effort, only two therapeutic options, with very limited effects, are available. The purinergic system has been indicated as a
Autor:
Isabella, Orienti, Monica, Armida, Gabriella, Dobrowolny, Rita, Pepponi, Gabriella, Sollazzini, Antonella, Pezzola, Irene, Casola, Antonio, Musarò, Patrizia, Popoli, Rosa Luisa, Potenza
Publikováno v:
Neuroscience. 473
Amyotrophic lateral sclerosis (ALS) is the most frequent motor neuron disease for which effective treatment options are still lacking. ALS occurs in sporadic and familial forms which are clinically indistinguishable; about 20% of familial ALS cases a
Autor:
Irene Casola, Antonella Pèzzola, Gabriella Dobrowolny, Isabella Orienti, Monica Armida, Rita Pepponi, Patrizia Popoli, Rosa Luisa Potenza, Gabriella Sollazzini, Antonio Musarò
Amyotrophic lateral sclerosis (ALS) is the most frequent motor neuron disease for which effective treatment options are still lacking. ALS occurs in sporadic and familial forms which are clinically indistinguishable; about 20% of familial ALS cases a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9211217c9ac6406c4454b183497df4c7
http://hdl.handle.net/11573/1568497
http://hdl.handle.net/11573/1568497
Autor:
Roberta De Simone, Monica Armida, Antonella Pèzzola, Laura Ricceri, Alessia Butera, Monica Boirivant, Rosa Luisa Potenza
Publikováno v:
Neuroscience. 435
Autism Spectrum Disorders (ASD) are neurodevelopmental disorders characterized by social communication deficits and repetitive/stereotyped behaviours. We evaluated the effects of a chronic treatment with the immunomodulator drug Fingolimod (FTY720