Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Rosa Karlic"'
Autor:
Marinela Krizanac, Paula Štancl, Paola Berenice Mass-Sanchez, Rosa Karlić, Diana Moeckel, Twan Lammers, Anastasia Asimakopoulos, Ralf Weiskirchen
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
IntroductionMetabolic dysfunction-associated fatty liver disease (MAFLD) has emerged as the leading cause of hepatocellular carcinoma (HCC) worldwide. Over the years, Perilipin 5 (PLIN5) has been recognized as a key regulator of both MAFLD and HCC de
Externí odkaz:
https://doaj.org/article/9a225a6bd56d487ba4820999a20b88ac
Autor:
Paola Berenice Mass-Sanchez, Marinela Krizanac, Paula Štancl, Marvin Leopold, Kathrin M. Engel, Eva Miriam Buhl, Josef van Helden, Nikolaus Gassler, Jürgen Schiller, Rosa Karlić, Diana Möckel, Twan Lammers, Steffen K. Meurer, Ralf Weiskirchen, Anastasia Asimakopoulos
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract The molecular mechanisms underlying the transition from nonalcoholic fatty liver disease (NAFLD) to hepatocellular carcinoma (HCC) are incompletely understood. During the development of NAFLD, Perilipin 5 (PLIN5) can regulate lipid metabolis
Externí odkaz:
https://doaj.org/article/2fdd9001212f423bba51c0fecc09dd17
Autor:
Andreja Petrović, Paula Štancl, Paula Gršković, Suzana Hančić, Rosa Karlić, Slavko Gašparov, Petra Korać
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10558 (2024)
Hepatocellular carcinoma (HCC) is the most prevalent primary liver cancer, ranking as the sixth most common cancer worldwide and the fourth leading cause of cancer-related deaths. Most HCC cases originate from cirrhotic livers, typically due to chron
Externí odkaz:
https://doaj.org/article/2307fc69c4ae4396bbb37c985da0de4d
Autor:
Anita Rogic, Ila Pant, Luca Grumolato, Ruben Fernandez-Rodriguez, Andrew Edwards, Suvendu Das, Aaron Sun, Shen Yao, Rui Qiao, Shabnam Jaffer, Ravi Sachidanandam, Guray Akturk, Rosa Karlic, Mihaela Skobe, Stuart A. Aaronson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Inflammatory breast cancer (IBC) is an aggressive form of breast cancer with a poor prognosis. Here the authors report the characterization of a human IBC cell line recapitulating the clinical and histopathological features of the human disease, and
Externí odkaz:
https://doaj.org/article/178a7e049b6748368cce8de609f3ab95
Autor:
Wei Jiao, Gurnit Atwal, Paz Polak, Rosa Karlic, Edwin Cuppen, PCAWG Tumor Subtypes and Clinical Translation Working Group, Alexandra Danyi, Jeroen de Ridder, Carla van Herpen, Martijn P. Lolkema, Neeltje Steeghs, Gad Getz, Quaid Morris, Lincoln D. Stein, PCAWG Consortium
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Some cancer patients first present with metastases where the location of the primary is unidentified; these are difficult to treat. In this study, using machine learning, the authors develop a method to determine the tissue of origin of a cancer base
Externí odkaz:
https://doaj.org/article/1eb66053b1d54801a9b93093526fbf22
Autor:
Wei Jiao, Gurnit Atwal, Paz Polak, Rosa Karlic, Edwin Cuppen, PCAWG Tumor Subtypes and Clinical Translation Working Group, Alexandra Danyi, Jeroen de Ridder, Carla van Herpen, Martijn P. Lolkema, Neeltje Steeghs, Gad Getz, Quaid D. Morris, Lincoln D. Stein, PCAWG Consortium
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/f3b78c29568a431fbf3f2c59497329d4
Autor:
Suvendu Das, Rui Qiao, Andrew K. Edwards, Stuart A. Aaronson, Ravi Sachidanandam, Ila Pant, Ruben Fernandez-Rodriguez, Luca Grumolato, Rosa Karlic, Shabnam Jaffer, Aaron Sun, Anita Rogic, Shen Yao, Mihaela Skobe, Guray Akturk
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Inflammatory Breast Cancer (IBC) is a highly aggressive malignancy with distinct clinical and histopathological features whose molecular basis is unresolved. Here we describe a human IBC cell line, A3250, that recapitulates key IBC features in a mous
Publikováno v:
N Engl J Med
Description of the development of Etiologic Index of BRCA1 and BRCA2, a proposed etiologic index, based on genomic variation in tumor cells and matched normal cells, that can be used to evaluate the relevance of germline pathogenic variants (GPVs) in
Autor:
Ruben Fernandez-Rodriguez, Sara Cuadrado-Castano, Aryana Javaheri, Yonina Bykov, Andrew Edwards, Ignacio Mena, Noelia Dasilva-Freire, Anita Rogic, Alice O. Kamphorst, Rosa Karlic, Amir Horowitz, Adolfo García-Sastre, Mihaela Skobe
Publikováno v:
Journal of Clinical Oncology. 40:e15050-e15050
e15050 Background: Avian paramyxoviruses (APMVs) are negative-sense, single-stranded RNA viruses, of which best known is APMV-1, commonly referred to as Newcastle disease virus (NDV). NDV has been extensively studied as an oncolytic virus (OV) and ha
Autor:
Gad Getz, Alan D. D'Andrea, Rosa Karlic, Yehuda Brody, Michael S. Lawrence, Yosef E. Maruvka, Andre Bernards, Julian M. Hess, Franziska Michor, Kent W. Mouw, Paz Polak, Lior Z. Braunstein, Prasanna Parasuraman, Atanas Kamburov, Nicholas J. Haradhvala, Adam J. Bass, Amnon Koren, Esther Rheinbay
Publikováno v:
Nat Biotechnol
Microsatellites (MSs) are tracts of variable-length repeats of short DNA motifs that exhibit high rates of mutation in the form of insertions or deletions (indels) of the repeated motif. Despite their prevalence, the contribution of somatic MS indels