Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Rosa Gallagher"'
Autor:
Giri R. Gnawali, Koichi Okumura, Karolina Perez, Rosa Gallagher, Julia Wulfkuhle, Emanuel F. Petricoin, Sathish Kumar Reddy Padi, Jeremiah Bearss, Zhiyong He, Wei Wang, Andrew S. Kraft
Publikováno v:
Med Chem Res
Compound VBT-5445 was identified as an inhibitor to block the association of Pim and the protein Enhancer of Decapping 3 (EDC3), a Pim substrate, which normally functions to enhance the decapping of messenger RNA (mRNA). It was also shown to inhibit
Autor:
Jennifer Richer, Nicole Spoelstra, Alyse Winchester, Julia Wulfkuhlue, Rosa Gallagher, Sharon Sams, Gregory Vidal, Peter Kabos, Jennifer Diamond, Elena Shagisultanova, Anosheh Afghahi, Jose Mayordomo, Tessa McSpadded, Gloria Crawford, Virginia Borges, Dexiang Gao, Emanuel Petricoin, Anthony Elias
Publikováno v:
Cancer Research. 82:P1-17
Background: The clinical implications of the androgen receptor (AR), particularly in the context of aromatase inhibitor (AI) refractory metastatic breast cancer (MBC), are unclear. While AR is associated with more indolent primary tumors, in the abse