Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Rosa E Blanco"'
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0255196 (2021)
Retinoic acid (RA) plays major roles during nervous system development, and during regeneration of the adult nervous system. We have previously shown that components of the RA signaling pathway are upregulated after optic nerve injury, and that exoge
Externí odkaz:
https://doaj.org/article/660d8313c02a4ca9805a3e5534d908c4
Autor:
Rosa E Blanco, Giam S Vega-Meléndez, Valeria De La Rosa-Reyes, Clarissa Del Cueto, Jonathan M Blagburn
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0209733 (2019)
We have previously shown that a single application of the growth factors ciliary neurotrophic factor (CNTF) or fibroblast growth factor 2 (FGF-2) to the crushed optic nerve of the frog, Rana pipiens, increases the numbers and elongation rate of regen
Externí odkaz:
https://doaj.org/article/819d06682b1047ec89b97c4c71d0ee65
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162626 (2016)
After lesions to the mammalian optic nerve, the great majority of retinal ganglion cells (RGCs) die before their axons have even had a chance to regenerate. Frog RGCs, on the other hand, suffer only an approximately 50% cell loss, and we have previou
Externí odkaz:
https://doaj.org/article/0955dc6eb3274206851fca691f7c684b
Autor:
Sarah Kim, Kathleen Ochoa, Sierra E. Melli, Fawad A. K. Yousufzai, Zerian D. Barrera, Aela A. Williams, Gianna McIntyre, Esteban Delgado, James N. Bolish, Collin M. Macleod, Mary Boghos, Hayden P. Lens, Alex G. Ramos, Vincent B. Wilson, Kelly Maloney, Zachary M. Padron, Amaal H. Khan, Rosa E. Blanco, Ileana Soto
Publikováno v:
Scientific Reports. 13
Purkinje cell (PC) loss occurs at an early age in patients and animal models of Niemann-Pick Type C (NPC), a lysosomal storage disease caused by mutations in the Npc1 or Npc2 genes. Although degeneration of PCs occurs early in NPC, little is known ab
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 11, p e0255196 (2021)
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE, Vol 16, Iss 11, p e0255196 (2021)
PLoS ONE, Vol 16, Iss 11 (2021)
Retinoic acid (RA) plays major roles during nervous system development, and during regeneration of the adult nervous system. We have previously shown that components of the RA signaling pathway are upregulated after optic nerve injury, and that exoge
Publikováno v:
The FASEB Journal. 33
Autor:
Harriet M. Jackson, Zachary M. Padron, Ileana Soto, Bridget R. Boyle, Fawad A. K. Yousufzai, Kayla K. Green, Victoria L. Kuhnel, Gareth R. Howell, Sierra E. Melli, Larisa Kavetsky, Rosa E. Blanco
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Niemann Pick Type-C disease (NPC) is an inherited lysosomal storage disease (LSD) caused by pathogenic variants in the Npc1 or Npc2 genes that lead to the accumulation of cholesterol and lipids in lysosomes. NPC1 deficiency causes neurodegeneration,
Publikováno v:
The FASEB Journal. 34:1-1
Autor:
Giam S. Vega-Meléndez, Rosa E. Blanco, Jonathan M. Blagburn, Clarissa Del Cueto, Valeria De La Rosa-Reyes
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0209733 (2019)
PLoS ONE
PLoS ONE
We have previously shown that a single application of the growth factors ciliary neurotrophic factor (CNTF) or fibroblast growth factor 2 (FGF-2) to the crushed optic nerve of the frog, Rana pipiens, increases the numbers and elongation rate of regen
Publikováno v:
Journal of Neuroscience Research. 92:13-23
Neurotrophins such as ciliary neurotrophic factor (CNTF) and brain-derived neurotrophic factor (BDNF) and growth factors such as fibroblast growth factor (FGF-2) play important roles in neuronal survival and in axonal outgrowth during development. Ho