Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Rosa Bellavita"'
Autor:
Rosa Bellavita, Annarita Falanga, Francesco Merlino, Gabriella D’Auria, Nicola Molfetta, Anella Saviano, Francesco Maione, Umberto Galdiero, Maria Rosaria Catania, Stefania Galdiero, Paolo Grieco, Emanuela Roscetto, Lucia Falcigno, Elisabetta Buommino
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1, Pp 36-50 (2023)
AbstractThe increasing resistance of fungi to conventional antifungal drugs has prompted worldwide the search for new compounds. In this work, we investigated the antifungal properties of acylated Temporin L derivatives, Pent-1B and Dec-1B, against C
Externí odkaz:
https://doaj.org/article/39c43ad04aa145468deb70d283b01f6c
Autor:
Roberta Pacifico, Nunzio Del Gaudio, Guglielmo Bove, Lucia Altucci, Lydia Siragusa, Gabriele Cruciani, Menotti Ruvo, Rosa Bellavita, Paolo Grieco, Mauro F. A. Adamo
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1987-1994 (2022)
We have recently developed a new synthetic methodology that provided both N-aryl-5-hydroxytriazoles and N-pyridine-4-alkyl triazoles. A selection of these products was carried through virtual screening towards targets that are contemporary and valida
Externí odkaz:
https://doaj.org/article/f9c5fcf1b41543b299f0dd8f3efb65c3
Publikováno v:
Bioinorganic Chemistry and Applications, Vol 2023 (2023)
Numerous supramolecular platforms inspired by natural self-assembly are exploited as drug delivery systems. The spontaneous arrangement of single building blocks into inorganic and organic structures is determined and controlled by noncovalent forces
Externí odkaz:
https://doaj.org/article/05aeef66dc8b4684a54314abb14b987a
Autor:
Teresa Barra, Annarita Falanga, Rosa Bellavita, Vincenza Laforgia, Marina Prisco, Stefania Galdiero, Salvatore Valiante
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The blood–brain barrier (BBB) selectively protects the central nervous system (CNS) from external insults, but its function can represent a limit for the passage of therapeutic molecules. Numerous in vitro models of the BBB have been realized in or
Externí odkaz:
https://doaj.org/article/aa967a2bf7ec408c8caabee288283262
Publikováno v:
Biomolecules, Vol 13, Iss 7, p 1021 (2023)
Fungi in the genus Talaromyces occur in every environment in both terrestrial and marine contexts, where they have been quite frequently found in association with plants and animals. The relationships of symbiotic fungi with their hosts are often med
Externí odkaz:
https://doaj.org/article/50e39e15098f47caa3d1ca4cfd217d2b
Publikováno v:
Pharmaceuticals, Vol 16, Iss 3, p 439 (2023)
Antimicrobial peptides (AMPs) have recently gained attention as a viable solution for combatting antibiotic resistance due to their numerous advantages, including their broad-spectrum activity, low propensity for inducing resistance, and low cytotoxi
Externí odkaz:
https://doaj.org/article/5734553a75f747348590d8ce437d2f8e
Autor:
Rosa Bellavita, Angela Maione, Simone Braccia, Marica Sinoca, Stefania Galdiero, Emilia Galdiero, Annarita Falanga
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3092 (2023)
Chronic lung infections in cystic fibrosis (CF) patients are triggered by multidrug-resistant bacteria such as Pseudomonas aeruginosa, Achromobacter xylosoxidans, and Stenotrophomonas maltophilia. The CF airways are considered ideal sites for the col
Externí odkaz:
https://doaj.org/article/ba63f39ed2a14cea8f1dbde5c9f000fc
Autor:
Rosa Bellavita, Annarita Falanga, Elisabetta Buommino, Francesco Merlino, Bruno Casciaro, Floriana Cappiello, Maria Luisa Mangoni, Ettore Novellino, Maria Rosaria Catania, Rossella Paolillo, Paolo Grieco, Stefania Galdiero
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1751-1764 (2020)
The rapid development of antimicrobial resistance is pushing the search in the discovering of novel antimicrobial molecules to prevent and treat bacterial infections. Self-assembling antimicrobial peptides, as the lipidated peptides, are a novel and
Externí odkaz:
https://doaj.org/article/fbb519ebab4547f6a5bf64777c38cefb
Neuroprotective Effects of gH625-lipoPACAP in an In Vitro Fluid Dynamic Model of Parkinson’s Disease
Autor:
Teresa Barra, Annarita Falanga, Rosa Bellavita, Jessica Pisano, Vincenza Laforgia, Marina Prisco, Stefania Galdiero, Salvatore Valiante
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2644 (2022)
Parkinson’s disease (PD) is an aggressive and devastating age-related disorder. Although the causes are still unclear, several factors, including genetic and environmental, are involved. Except for symptomatic drugs, there are not, to date, any rea
Externí odkaz:
https://doaj.org/article/d77e01220d2347adbc9694f84d1114fd
Autor:
Carlo Gesualdo, Cornel Balta, Chiara Bianca Maria Platania, Maria Consiglia Trotta, Hildegard Herman, Sami Gharbia, Marcel Rosu, Francesco Petrillo, Salvatore Giunta, Alberto Della Corte, Paolo Grieco, Rosa Bellavita, Francesca Simonelli, Michele D’Amico, Anca Hermenean, Settimio Rossi, Claudio Bucolo
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
This study aimed to investigate the interactions between fingolimod, a sphingosine 1-phosphate receptor (S1PR) agonist, and melanocortin receptors 1 and 5 (MCR1, MCR5). In particular, we investigated the effects of fingolimod, a drug approved to trea
Externí odkaz:
https://doaj.org/article/8e236853c3f9447d8a2332342fb239dd