Zobrazeno 1 - 10 of 32 pro vyhledávání: '"Rosário Dominguez Crespo Hirata"'
1
Akademický článek
Genotyping of Mycobacterium tuberculosis isolates from alow-endemic setting in northwestern state of Paraná in Southern Brazil
Autor: Erika Noda Noguti, Clarice Queico Fujimura Leite, Ana Carolina Malaspina, Adolfo Carlos Barreto Santos, Rosário Dominguez Crespo Hirata, Mario Hiroyuki Hirata, Elsa Massae Mamizuka, Rosilene Fressatti Cardoso
Publikováno v: Memorias do Instituto Oswaldo Cruz, Vol 105, Iss 6, Pp 779-785 (2010)
The purpose of this study was to provide information about the genetic diversity and prevalent genotype of Mycobacterium tuberculosis in a low-endemic setting in northwestern state of Paraná in Southern Brazil. We employed spoligotyping and mycobact
Externí odkaz: https://doaj.org/article/45873b408a44426aaa5d7f474c96635a
Zobrazit plný text záznamu
2
Akademický článek
Characterization of ndh gene of isoniazid resistant and susceptible Mycobacterium tuberculosis isolates from Brazil
Autor: Rosilene Fressatti Cardoso, Marco Antonio Cardoso, Clarice Queico Fujimura Leite, Daisy Nakamura Sato, Elsa Masae Mamizuka, Rosário Dominguez Crespo Hirata, Fernando Fiúza de Mello, Mario Hiroyuki Hirata
Publikováno v: Memorias do Instituto Oswaldo Cruz, Vol 102, Iss 1, Pp 59-61 (2007)
Resistance in Mycobacterium tuberculosis to isoniazid (INH) is caused by mutations in the catalase-peroxidase gene (katG) , and within the inhA promoter and/or in structural gene. A small percentage (~ 10%) of INH-resistant strains do not present mut
Externí odkaz: https://doaj.org/article/e09efce34fef418899fd11f61f362a8e
Zobrazit plný text záznamu
3
Akademický článek
The low-density lipoprotein receptor-related protein 5 (LRP5) 4037C>T polymorphism: candidate for susceptibility to type 1 diabetes mellitus
Autor: Karla Simone Costa de Souza, Marcela Abbott Galvão Ururahy, Yonara Monique da Costa Oliveira, Melina Bezerra Loureiro, Heglayne Pereira Vital da Silva, Raul Hernandes Bortolin, André Ducati Luchessi, Ricardo Fernando Arrais, Rosário Dominguez Crespo Hirata, Maria das Graças Almeida, Mário Hiroyuki Hirata, Adriana Augusto de Rezende
Publikováno v: Archives of Endocrinology and Metabolism, Vol 62, Iss 4, Pp 480-484
ABSTRACT Objective: The present study has investigated the association between low-density lipoprotein receptor-related protein 5 (LRP5) 4037C>T polymorphism and type 1 diabetes mellitus (T1DM) susceptibility in a Brazilian population. Subjects and m
Externí odkaz: https://doaj.org/article/ef8965f1dca64b0692004c5059f1f1bf
Zobrazit plný text záznamu
4
Akademický článek
TREML4 polymorphisms increase the mRNA in blood leukocytes in the progression of atherosclerosis
Autor: Victor Hugo Rezende Duarte, Marina Sampaio Cruz, Adriana Bertolami, Mario Hiroyuki Hirata, Rosario Dominguez Crespo Hirata, André Ducati Luchessi, Vivian Nogueira Silbiger
Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract TREML4 and other members of the triggering receptor expressed in the myeloid cell family are associated with a risk of atherosclerosis and progression in coronary artery disease, acute coronary syndrome, and coronary artery calcification. He
Externí odkaz: https://doaj.org/article/b536ef4704e14459bdc95dbe8ed971f7
Zobrazit plný text záznamu
5
Akademický článek
The let-7b-5p, miR-326, and miR-125a-3p are associated with left ventricular systolic dysfunction in post-myocardial infarction
Autor: Raquel Costa Silva Dantas-Komatsu, Marina Sampaio Cruz, Paula Paccielli Freire, Rosiane Viana Zuza Diniz, Raul Hernandes Bortolin, Otávio Cabral-Marques, Kamilla Batista da Silva Souza, Mario Hiroyuki Hirata, Rosario Dominguez Crespo Hirata, Bruna Zavarize Reis, Igor Jurisica, Vivian Nogueira Silbiger, Andre Ducati Luchessi
Publikováno v: Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundAcute ST-elevation myocardial infarction (STEMI) can lead to adverse cardiac remodeling, resulting in left ventricular systolic dysfunction (LVSd) and heart failure. Epigenetic regulators, such as microRNAs, may be involved in the physiopat
Externí odkaz: https://doaj.org/article/e4ccea2392ee48ab8cc12fe422633058
Zobrazit plný text záznamu
6
Terapia gênica, doping genético e esporte: fundamentação e implicações para o futuro Gene therapy, genetic doping and sport: fundaments and implications for the future
Autor: Guilherme Giannini Artioli, Rosário Dominguez Crespo Hirata, Antonio Herbert Lancha Junior
Publikováno v: Revista Brasileira de Medicina do Esporte, Vol 13, Iss 5, Pp 349-354 (2007)
A busca pelo desempenho ótimo tem sido uma constante no esporte de alto rendimento. Para tanto, muitos atletas acabam utilizando drogas e métodos ilícitos, os quais podem ter importantes efeitos adversos. A terapia gênica é uma modalidade terap
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doajarticles::84c5314b57a3adcd7da2d242d15d93f7
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-86922007000500013
Zobrazit plný text záznamu
8
Akademický článek
Pharmacogenomics of mycophenolic acid in kidney transplantation: Contribution of immune response-related genes
Autor: Rosario Dominguez Crespo Hirata, Fabiana Dalla Vecchia Genvigir, Thiago Dominguez Crespo Hirata, Alvaro Cerda, Mario Hiroyuki Hirata
Publikováno v: Brazilian Journal of Pharmaceutical Sciences, Vol 58 (2023)
Abstract Mycophenolic acid (MPA) inhibits IMPDH, involved in the guanosine nucleotides synthesis, and prevents DNA replication in immune cells. The repression of cell and humoral immunity by MPA induces allograft tolerance preventing acute rejection
Externí odkaz: https://doaj.org/article/ec72674940c44452914d9844cc10747f
Zobrazit plný text záznamu
9
Akademický článek
Genetic Variant ABCC1 rs45511401 Is Associated with Increased Response to Statins in Patients with Familial Hypercholesterolemia
Autor: Carolina Dagli-Hernandez, Jéssica Bassani Borges, Elisangela da Silva Rodrigues Marçal, Renata Caroline Costa de Freitas, Augusto Akira Mori, Rodrigo Marques Gonçalves, Andre Arpad Faludi, Victor Fernandes de Oliveira, Glaucio Monteiro Ferreira, Gisele Medeiros Bastos, Yitian Zhou, Volker M. Lauschke, Alvaro Cerda, Mario Hiroyuki Hirata, Rosario Dominguez Crespo Hirata
Publikováno v: Pharmaceutics, Vol 14, Iss 5, p 944 (2022)
Statins are the first-line treatment for familial hypercholesterolemia (FH), but response is highly variable due to genetic and nongenetic factors. Here, we explored the association between response and genetic variability in 114 Brazilian adult FH p
Externí odkaz: https://doaj.org/article/ea95afb671784795ae2502ff288ed59a
Zobrazit plný text záznamu
10
Akademický článek
Circulating Extracellular Vesicles As Biomarkers and Drug Delivery Vehicles in Cardiovascular Diseases
Autor: Renata Caroline Costa de Freitas, Rosario Dominguez Crespo Hirata, Mario Hiroyuki Hirata, Elena Aikawa
Publikováno v: Biomolecules, Vol 11, Iss 3, p 388 (2021)
Extracellular vesicles (EVs) are composed of a lipid bilayer containing transmembrane and soluble proteins. Subtypes of EVs include ectosomes (microparticles/microvesicles), exosomes, and apoptotic bodies that can be released by various tissues into
Externí odkaz: https://doaj.org/article/054107eabfec48eeaee4b55af72a7fb2
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje