Genetic mapping of distal femoral, stifle, and tibial radiographic morphology in dogs with cranial cruciate ligament disease.

Autor: Eleni Healey, Rachel J Murphy, Jessica J Hayward, Marta Castelhano, Adam R Boyko, Kei Hayashi, Ursula Krotscheck, Rory J Todhunter

Publikováno v: PLoS ONE, Vol 14, Iss 10, p e0223094 (2019)

Cranial cruciate ligament disease (CCLD) is a complex trait. Ten measurements were made on orthogonal distal pelvic limb radiographs of 161 pure and mixed breed dogs with, and 55 without, cranial cruciate partial or complete ligament rupture. Dogs wi

Externí odkaz: https://doaj.org/article/f3ce6ccc3a5948e7a06bc6c294532b45

Monitoring Hip and Elbow Dysplasia achieved modest genetic improvement of 74 dog breeds over 40 years in USA.

Autor: Yali Hou, Yachun Wang, Xuemei Lu, Xu Zhang, Qian Zhao, Rory J Todhunter, Zhiwu Zhang

Publikováno v: PLoS ONE, Vol 8, Iss 10, p e76390 (2013)

Hip (HD) and Elbow Dysplasia (ED) are two common complex developmental disorders of dogs. In order to decrease their prevalence and severity, the Orthopedic Foundation for Animals (OFA) has a voluntary registry of canine hip and elbow conformation ce

Externí odkaz: https://doaj.org/article/495bbe70574c46e09f8a53231a0d8516

Retrospective analysis for genetic improvement of hip joints of cohort labrador retrievers in the United States: 1970-2007.

Autor: Yali Hou, Yachun Wang, George Lust, Lan Zhu, Zhiwu Zhang, Rory J Todhunter

Publikováno v: PLoS ONE, Vol 5, Iss 2, p e9410 (2010)

Canine Hip Dysplasia (CHD) is a common inherited disease that affects dog wellbeing and causes a heavy financial and emotional burden to dog owners and breeders due to secondary hip osteoarthritis. The Orthopedic Foundation for Animals (OFA) initiate

Externí odkaz: https://doaj.org/article/1af293b4e1154b369ca3fd141dee0858

Complex Feline Disease Mapping Using a Dense Genotyping Array

Autor: Isabel Hernandez, Jessica J. Hayward, Jeff A. Brockman, Michelle E. White, Lara Mouttham, Elizabeth A. Wilcox, Susan Garrison, Marta G. Castelhano, John P. Loftus, Filipe Espinheira Gomes, Cheryl Balkman, Marjory B. Brooks, Nadine Fiani, Marnin Forman, Tom Kern, Bruce Kornreich, Eric Ledbetter, Santiago Peralta, Angela M. Struble, Lisa Caligiuri, Elizabeth Corey, Lin Lin, Julie Jordan, Danny Sack, Adam R. Boyko, Leslie A. Lyons, Rory J. Todhunter

Publikováno v: Frontiers in veterinary science. 9

The current feline genotyping array of 63k single nucleotide polymorphisms has proven its utility within breeds, and its use has led to the identification of variants associated with Mendelian traits in purebred cats. However, compared to single gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae226b7e8690cc43aadb385c53197fe6
https://pubmed.ncbi.nlm.nih.gov/35782544

Spontaneous dog osteoarthritis — a One Medicine vision

Autor: George Nuki, Rory J. Todhunter, Andrew A. Pitsillides, Richard Meeson, Gordon Blunn

Publikováno v: Nature Reviews. Rheumatology
Meeson, R L, Todhunter, R J, Blunn, G, Nuki, G & Pitsillides, A A 2019, ' Spontaneous dog osteoarthritis — a One Medicine vision ', Nature Reviews Rheumatology, vol. 15, no. 5, pp. 273-287 . https://doi.org/10.1038/s41584-019-0202-1

Osteoarthritis (OA) is a global disease that, despite extensive research, has limited treatment options. Pet dogs share both an environment and lifestyle attributes with their owners, and a growing awareness is developing in the public and among rese

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c36d725b177eb4a86850a15d8f33877d
http://europepmc.org/articles/PMC7097182