Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Rory Geyer"'
Autor:
Paola Peshkepija, Wei Zhou, Chun Yu, Elizabeth Fleming, Karolina Palucka, Kin-Hoe Chow, Rory Geyer, Julia Oh
Human gut microbiota has co-evolved with human, and plays important roles in regulating the development and functioning of the host immune system. To study the human-specific microbiome-immunune interaction in an animal model is challenging as the an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::320be0e60ae4e33cf2f189c4479f47f9
https://doi.org/10.1101/2021.10.06.463343
https://doi.org/10.1101/2021.10.06.463343
Publikováno v:
The Journal of Immunology. 208:119.07-119.07
The neuroimmune response to stress has been linked to enhanced tumor proliferation, angiogenesis, and metastasis. In particular, signaling through β-adrenergic receptors has been demonstrated to promote a highly immunosuppressive tumor microenvironm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a460818adc851f515877dc708b241a4
https://doi.org/10.4049/jimmunol.208.supp.119.07
https://doi.org/10.4049/jimmunol.208.supp.119.07
Publikováno v:
The Journal of Immunology. 208:169.10-169.10
The sympathetic nervous system (SNS) innervates all lymphoid tissues and is, thus, well-positioned to influence the activity of immune cells. Accordingly, the coordinated responses of the SNS and immune system are crucial for immune responses to infe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89a340e1926d10b43eeb35b288d8c3ef
https://doi.org/10.4049/jimmunol.208.supp.169.10
https://doi.org/10.4049/jimmunol.208.supp.169.10
Publikováno v:
The Journal of Immunology. 206:98.34-98.34
Natural killer (NK) cells play a critical role in immune responses to certain viral infections and cancers by directly killing infected or transformed cells and producing cytokines that may enhance the function of other immune cells. NK cell effector
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9a405b234d455deb5f4ec67d0e41b26
https://doi.org/10.4049/jimmunol.206.supp.98.34
https://doi.org/10.4049/jimmunol.206.supp.98.34
Publikováno v:
Journal of Biological Chemistry. 288:6640-6650
Syx is a Rho-specific guanine nucleotide exchange factor (GEF) that localizes at cell-cell junctions and promotes junction stability by activating RhoA and the downstream effector Diaphanous homolog 1 (Dia1). Previously, we identified several molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61baab1157c73d861d39a65caee341d7
https://doi.org/10.1074/jbc.m112.432682
https://doi.org/10.1074/jbc.m112.432682
Autor:
Masahiro Yanagisawa, Derek C. Radisky, Evette S. Radisky, Rory Geyer, Lidiya Orlichenko, Panos Z. Anastasiadis, Davitte Khauv
Publikováno v:
Journal of Biological Chemistry. 285:19153-19161
The Rac1b splice isoform contains a 19-amino acid insertion not found in Rac1; this insertion leads to decreased GTPase activity and reduced affinity for GDP, resulting in the intracellular predominance of GTP-bound Rac1b. Here, using co-precipitatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a94ec5c7f440dc4bf12c405c6ca5b32b
https://doi.org/10.1074/jbc.m109.099382
https://doi.org/10.1074/jbc.m109.099382
Autor:
Siu P. Ngok, Laura J. Lewis-Tuffin, Lauren Johnston, Ryan W. Feathers, Rory Geyer, Panos Z. Anastasiadis, Antonis Kourtidis, Justus C. Dachsel
The role of RhoA in promoting directed cell migration has been complicated by studies showing that it is activated both in the front and the rear of migrating cells. We report here that the RhoA-specific guanine nucleotide exchange factor Syx is requ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad23073ae3b37abe7165f1d7b9f732ce
https://europepmc.org/articles/PMC3889543/
https://europepmc.org/articles/PMC3889543/
Autor:
Channing J. Der, Panos Z. Anastasiadis, Ryan W. Feathers, Rory Geyer, Natalia Mitin, Antonis Kourtidis, Siu P. Ngok
Publikováno v:
Journal of Cell Science.
Signaling events mediated by Rho family GTPases orchestrate cytoskeletal dynamics and cell junction formation. The activation of Rho GTPases is tightly regulated by guanine nucleotide exchange-factors (GEFs). In this study, we identified a novel Rhos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f13d731bade89300d9c05389cb2172d
https://doi.org/10.1242/jcs.123869
https://doi.org/10.1242/jcs.123869
Autor:
Karen L Moodie, Jay M. Baraban, Laura J. Lewis-Tuffin, Deborah Huveldt, Miaoliang Liu, Sudesh Agrawal, Antonis Kourtidis, Chuanshen Wu, Siu P. Ngok, Arie Horowitz, Peter Storz, Himabindu Reddy Seerapu, Ruth Marx, Panos Z. Anastasiadis, Rory Geyer
Publikováno v:
The Journal of Cell Biology
VEGF causes translocation of Syx from endothelial cell junctions, promoting junction disassembly, whereas Angtiopoietin-1 maintains Syx at the junctions and stabilizes them.
Vascular endothelial growth factor (VEGF) and Ang1 (Angiopoietin-1) hav
Vascular endothelial growth factor (VEGF) and Ang1 (Angiopoietin-1) hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65402e51baa2d64a92cf65afde19e7d0
https://pubmed.ncbi.nlm.nih.gov/23253477
https://pubmed.ncbi.nlm.nih.gov/23253477
Autor:
Ngok, Siu P., Geyer, Rory, Kourtidis, Antonis, Mitin, Natalia, Feathers, Ryan, Der, Channing, Anastasiadis, Panos Z.
Publikováno v:
Journal of Cell Science; Aug2013, Vol. 126 Issue 15, p3271-3277, 7p