Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Rory F. Finn"'
Autor:
Brad Evans, Keith A. Davis, Joe T. Collins, Keshab Bhattacharya, Anouk Dirksen, Jari I. Finneman, Paul W. Brown, Erin Pepin, Jeffrey S. Ryczek, Ratish Mangalathillam, William B. Wellborn, Mark John Pozzo, Rory F. Finn
Publikováno v:
Biopolymers.
A scalable, viable process was developed for the Fibroblast Growth Factor 21 (FGF21) protein-antibody conjugate, CVX-343, an extended half-life therapeutic for the treatment of metabolic disease. CVX-343 utilizes the CovX antibody scaffold technology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88789a43a56b3aaa1e140488c09b7a9f
https://pubmed.ncbi.nlm.nih.gov/28948603
https://pubmed.ncbi.nlm.nih.gov/28948603
Autor:
Rory F. Finn, Roger H. Pak
Publikováno v:
Sterile Product Development ISBN: 9781461479772
This chapter will begin with a brief review of the PEGylated biotherapeutic product landscape (commercial products and known molecules in development) and then discuss various product development approaches and issues. Several topics pertinent to PEG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8ceedfa0f1cfb07ecf68c6c3c44e5c4
https://doi.org/10.1007/978-1-4614-7978-9_4
https://doi.org/10.1007/978-1-4614-7978-9_4
Autor:
Mark W. Naylor, Rory F. Finn, Stephen G. Rogers, Richard M. Leimgruber, Roy L. Fuchs, Kimberly M. Magin, Andrew J. Reed, Bruce G. Hammond, Keith A. Kretzmer
Publikováno v:
Journal of Agricultural and Food Chemistry. 44:388-394
Tomato plants with delayed fruit ripening have been produced by stable insertion of the gene encoding the 1-aminocyclopropane-1-carboxylic acid deaminase (ACCd) protein into the tomato chromosome. Two approaches were used to assess the safety of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8b184a65b4e2211dda09e10ad049166
https://doi.org/10.1021/jf9504071
https://doi.org/10.1021/jf9504071
Autor:
Jennings Michael Girard, Denis M. Boyle, Nancy M. Kimack, Christine E. Smith, Rory F. Finn, Kimberly M. Magin, Roy L. Fuchs, Ronald B. Frazier, Andrew J. Reed, Richard M. Leimgruber, Bruce F. Bishop
Publikováno v:
Journal of Agricultural and Food Chemistry. 44:381-387
Tomato plants with delayed fruit ripening have been developed by introduction of the gene encoding the 1-aminocyclopropane-1-carboxylic acid deaminase (ACCd) protein into the tomato genome. The ACCd enzyme delays fruit ripening by decreasing ethylene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24d1035013ca1b7eb6b85b24e831e1cb
https://doi.org/10.1021/jf9504069
https://doi.org/10.1021/jf9504069
Autor:
William J. Salsgiver, Sharon A. Berberich, George Irvin Glover, Shaukat H. Rangwala, Christine E. Smith, Peter O. Olins, Rory F. Finn, William C. Stallings
Publikováno v:
Gene. 122:263-269
High levels of active HIV-1 protease (PR) were produced in Escherichia coli, amounting to 8–10% of total cell protein. High production levels were achieved by altering the following parameters: (1) codon preference of the coding region, (2) A + T-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2058c7c2de7fba4ccca37f1c5d327df0
https://doi.org/10.1016/0378-1119(92)90214-a
https://doi.org/10.1016/0378-1119(92)90214-a
Autor:
Rory F. Finn
Publikováno v:
PEGylated Protein Drugs: Basic Science and Clinical Applications ISBN: 9783764386788
Recombinant human growth hormone (hGH) is a well characterized molecule with broad acceptance as a treatment for growth hormone deficiencies (GHD). However, treatment with hGH requires daily injections due to the drug’s short duration of action. Ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f15d15542e86ca21fe40fd4af33d3b1
https://doi.org/10.1007/978-3-7643-8679-5_11
https://doi.org/10.1007/978-3-7643-8679-5_11
Autor:
Janet C. Mayden, Charles Steven Schasteen, Rory F. Finn, George Irvin Glover, Sharon A. McLafferty, Lea D. Bullock, R. Paul Levine
Publikováno v:
Molecular Immunology. 28:17-26
Synthetic peptides based on functionally equivalent (as defined by similar patterns of chemically equivalent amino acids) serine protease inhibitor (serpin) C-terminal sequences inhibit both classical and alternative pathways of complement activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a782ce7d7c4f9ce28b1e8aa5210b368b
https://doi.org/10.1016/0161-5890(91)90082-u
https://doi.org/10.1016/0161-5890(91)90082-u
Autor:
John P. Mckearn, Daniel B. Casey, Rory F. Finn, Ann M. Farese, Thomas J. MacVittie, Walter G. Smith, Ned R. Siegel, R. M. Vigneulle, Jon A. Klover
Publikováno v:
Stem cells (Dayton, Ohio). 19(6)
Leridistim, a member of the myelopoietin family of dual receptor agonists that binds interleukin-3 and G-CSF receptors, has been shown to enhance hematopoietic activity in rhesus monkeys above that observed with either cytokine alone or in combinatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ec81796a7a9e7b9f8531b4693cc13e7
https://pubmed.ncbi.nlm.nih.gov/11713343
https://pubmed.ncbi.nlm.nih.gov/11713343
Autor:
David E. Bartnicki, Robert A. Heeren, Richard M. Leimgruber, Mark Edward Gustafson, Arnold Hershman, Sharon A. Berberich, Glen J. Rogan, Roy L. Fuchs, Rory F. Finn
Publikováno v:
Bio/technology (Nature Publishing Company). 11(13)
The gene encoding neomycin phosphotransferase II (NPTII) has been used routinely as a selectable marker in the production of genetically engineered crops. To facilitate the safety assessment of this protein, the same coding sequence used for plant tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::755ab32e467496691d046c4833fbcfba
https://pubmed.ncbi.nlm.nih.gov/7764243
https://pubmed.ncbi.nlm.nih.gov/7764243
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