Výsledky vyhledávání - "Rory D. Manion"

The expression of Nectin-4 on the surface of ovarian cancer cells alters their ability to adhere, migrate, aggregate, and proliferate

Autor: Petra C. Buchanan, Rory D. Manion, Kristin L.M. Boylan, Amy P.N. Skubitz, Dip M. Shukla, Cody Bruggemeyer, Kelly Braumberger

Publikováno v: Oncotarget

// Kristin L.M. Boylan 1 , Petra C. Buchanan 1 , Rory D. Manion 1 , Dip M. Shukla 1 , Kelly Braumberger 1 , Cody Bruggemeyer 1 , Amy P.N. Skubitz 1 1 Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA Corre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6524d8dc84c0277ea6d23a97f4172b83
https://doi.org/10.18632/oncotarget.14206

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Abstract A06: Synthetic peptides derived from the cell adhesion molecule Nectin-4 inhibit the formation of ovarian cancer 3D spheroids

Autor: Rory D. Manion, Heena Shah, Kristin L.M. Boylan, Amy P.N. Skubitz

Publikováno v: Clinical Cancer Research. 26:A06-A06

A unique aspect of ovarian cancer progression is the collection of ascites fluid in the abdominal cavity, which contains free-floating tumor cells in the form of single cells and also multicellular aggregates or spheroids. Spheroids are more resistan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0dfbed66d70d150b2ff2d79ae3497c8d
https://doi.org/10.1158/1557-3265.ovca19-a06

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Inhibition of Ovarian Cancer Cell Spheroid Formation by Synthetic Peptides Derived from Nectin-4

Autor: Keith M. Skubitz, Kristin L.M. Boylan, Rory D. Manion, Amy P.N. Skubitz, Heena Shah

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 4637, p 4637 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 13

The formation of 3D multicellular spheroids in the ascites fluid of ovarian cancer patients is an understudied component of the disease progression. Spheroids are less sensitive to chemotherapy, in part due to the protection afforded by their structu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aaaf2e28d54b25b2f2bc14c187be5fd
https://doi.org/10.3390/ijms21134637

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Propranolol Decreases Proliferation of Endothelial Cells Transformed by Kaposi's Sarcoma-Associated Herpesvirus and Induces Lytic Viral Gene Expression

Autor: Ryan S. Hanson, Shane C McAllister, Rory D. Manion

Publikováno v: Journal of virology. 89(21)

Kaposi's sarcoma (KS) is common in Africa, but economic constraints hinder successful treatment in most patients. Propranolol, a generic β-adrenergic antagonist, decreased proliferation of KS-associated herpesvirus (KSHV)-infected cells. Downregulat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01dbc43e00d3cc4cadb18d11f7964888
https://pubmed.ncbi.nlm.nih.gov/26269192

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