Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Rory Cristiane Fortes De Brito"'
Autor:
Lívia Mendes Carvalho, Francielle Carvalho Ferreira, Miriã Rodrigues Gusmão, Ana Flávia Pereira Costa, Rory Cristiane Fortes de Brito, Rodrigo Dian de Oliveira Aguiar-Soares, Alexandre Barbosa Reis, Jamille Mirelle de Oliveira Cardoso, Cláudia Martins Carneiro, Bruno Mendes Roatt, Ph.D
Publikováno v:
Current Research in Immunology, Vol 2, Iss , Pp 194-201 (2021)
Visceral leishmaniasis (VL) is a serious and neglected disease present worldwide. Chemotherapy using pentavalent antimony (SbV) is the most practical and inexpensive strategy available for the VL treatment today, however, it has high toxicity. Altern
Externí odkaz:
https://doaj.org/article/f03595e11cd24ad6a43095b62d4d2318
Autor:
Fernando Augusto Siqueira Mathias, Thais Lopes Valentim Di Paschoale Ostolin, Levi Eduardo Soares Reis, Jamille Mirelle de Oliveira Cardoso, Rory Cristiane Fortes De Brito, Rodrigo Dian de Oliveira Aguiar Soares, Bruno Mendes Roatt, Paula Melo de Abreu Vieira, Alexandre Barbosa Reis
Publikováno v:
Vaccines, Vol 11, Iss 2, p 395 (2023)
Background: The adjuvants’ optimal dose and the administration route can directly influence the epitope recognition patterns and profiles of innate response. We aimed to establish the effect and the optimal dose of adjuvant systems for proposing a
Externí odkaz:
https://doaj.org/article/d9d66d177a5f456a8c7df4cb3f7e576b
Autor:
Rodrigo Dian de Oliveira Aguiar-Soares, Bruno Mendes Roatt, Fernando Augusto Siqueira Mathias, Levi Eduardo Soares Reis, Jamille Mirelle de Oliveira Cardoso, Rory Cristiane Fortes de Brito, Henrique Gama Ker, Rodrigo Corrêa-Oliveira, Rodolfo Cordeiro Giunchetti, Alexandre Barbosa Reis
Publikováno v:
Vaccines, Vol 8, Iss 4, p 690 (2020)
In this study, we performed a phase I and II clinical trial in dogs to evaluate the toxicity and immunogenicity of LBSap-vaccine prototype, in comparison to Leishmune® and Leish-Tec® vaccines. Twenty-eight dogs were classified in four groups: (i) c
Externí odkaz:
https://doaj.org/article/f4679362f3784d5ca840d68a75cccafc
Autor:
Rory Cristiane Fortes De Brito, Jeronimo Conceição Ruiz, Jamille Mirelle de Oliveira Cardoso, Thais Lopes Valentim Di Paschoale Ostolin, Levi Eduardo Soares Reis, Fernando Augusto Siqueira Mathias, Rodrigo Dian de Oliveira Aguiar-Soares, Bruno Mendes Roatt, Rodrigo Corrêa-Oliveira, Daniela de Melo Resende, Alexandre Barbosa Reis
Publikováno v:
Vaccines, Vol 8, Iss 2, p 252 (2020)
Many vaccine candidates against visceral leishmaniasis (VL) have been proposed; however, to date, none of them have been efficacious for the human or canine disease. On this basis, the design of leishmaniasis vaccines has been constantly changing, an
Externí odkaz:
https://doaj.org/article/15f7aa4379184d07be04dad0e77b068f
Autor:
Rory Cristiane Fortes De Brito, Jamille Mirelle de Oliveira Cardoso, Levi Eduardo Soares Reis, Fernando Augusto Siqueira Mathias, Rodrigo Dian de Oliveira Aguiar-Soares, Andréa Teixeira-Carvalho, Bruno Mendes Roatt, Rodrigo Corrêa-Oliveira, Jeronimo Conceição Ruiz, Daniela de Melo Resende, Alexandre Barbosa Reis
Publikováno v:
Vaccines, Vol 7, Iss 4, p 162 (2019)
Reverse vaccinology or immunoinformatics is a computational methodology which integrates data from in silico epitope prediction, associated to other important information as, for example, the predicted subcellular location of the proteins used in the
Externí odkaz:
https://doaj.org/article/846a2a9d7b6d47d396d8111a020f5ce7
Autor:
João Filipe Pereira Vieira, Jamille Mirelle de Oliveira Cardoso, Rory Cristiane Fortes de Brito, Bruno Mendes Roatt, Cláudia Martins Carneiro, Diogo Garcia Valadares, Rodrigo Dian de Oliveira Aguiar-Soares, Alexandre Barbosa Reis
Publikováno v:
Molecular Immunology. 151:61-69
Autor:
Miriã Rodrigues Gusmão, Thaís Lopes Valentim Di Paschoali Ostolin, Lívia Mendes Carvalho, Ana Flávia Pereira Costa, Gabriel José Lucas Moreira, Jamille Mirelle de Oliveira Cardoso, Rodrigo Dian de Oliveira Aguiar-Soares, Alexandre Barbosa Reis, Rory Cristiane Fortes de Brito, Bruno Mendes Roatt
Publikováno v:
Vaccine. 40:5494-5503
In recent years, several advances have been observed in vaccinology especially for neglected tropical diseases (NTDs). One of the tools employed is epitope prediction by immunoinformatic approaches that reduce the time and cost to develop a vaccine.
Autor:
Isabela de Andrade Ferraz, Ana Maria Ravena Severino Carvalho, Rory Cristiane Fortes de Brito, Bruno Mendes Roatt, Vívian Tamietti Martins, Daniela Pagliara Lage, Luiza dos Reis Cruz, Fernanda Alvarenga Cardoso Medeiros, Denise Utsch Gonçalves, Manoel Otávio da Costa Rocha, Eduardo Antonio Ferraz Coelho, Tiago Antônio de Oliveira Mendes, Mariana Costa Duarte, Daniel Menezes-Souza
Publikováno v:
Applied Microbiology and Biotechnology. 106:4627-4641
Autor:
Thais Lopes Valentim Di Paschoale Ostolin, Alexandre Barbosa Reis, Bruno Mendes Roatt, Rory Cristiane Fortes de Brito, Fernando Augusto Siqueira Mathias, Frédéric Frézard, Guilherme Santos Ramos, Jamille Mirelle de Oliveira Cardoso, Hélida Monteiro de Andrade, João Filipe Pereira Vieira, Rodrigo Dian de Oliveira Aguiar-Soares, Levi Eduardo Soares Reis
Publikováno v:
Molecular Immunology. 141:70-78
This study compared the therapeutic potential of the chemotherapy using meglumine antimoniate encapsulated in a mixture of conventional and PEGylated liposomes (Nano Sbv) and immunotherapy with anti-canine IL-10 receptor-blocking monoclonal antibody
Autor:
João Filipe Pereira, Vieira, Jamille Mirelle, de Oliveira Cardoso, Rory Cristiane Fortes, de Brito, Bruno Mendes, Roatt, Cláudia Martins, Carneiro, Diogo Garcia, Valadares, Rodrigo Dian, de Oliveira Aguiar-Soares, Alexandre Barbosa, Reis
Publikováno v:
Molecular immunology. 151
Dogs are the most common domestic reservoir of Leishmania infantum, making canine visceral leishmaniasis (CVL) a serious public health issue. Identifying new methodologies that can mimic lymphoid and myeloid competence in naturally infected dogs coul