Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Rory A Fisher"'
Publikováno v:
PLoS Genetics, Vol 10, Iss 12, p e1004863 (2014)
Parkinson disease (PD) is characterized by the preferential, but poorly understood, vulnerability to degeneration of midbrain dopaminergic (mDA) neurons in the ventral substantia nigra compacta (vSNc). These sensitive mDA neurons express Pitx3, a tra
Externí odkaz:
https://doaj.org/article/1f472d059cf24ab8a8d4e9e26821ca85
Publikováno v:
PLoS Genetics, Vol 6, Iss 7, p e1001020 (2010)
Vertebrate development requires communication among cells of the embryo in order to define the body axis, and the Wnt-signaling network plays a key role in axis formation as well as in a vast array of other cellular processes. One arm of the Wnt-sign
Externí odkaz:
https://doaj.org/article/a5007ca04d574ad3a18b66bf9b0677e3
Autor:
Mackenzie M. Spicer, Jianqi Yang, Daniel Fu, Alison N. DeVore, Marisol Lauffer, Nilufer S. Atasoy, Deniz Atasoy, Rory A. Fisher
Hippocampal neuronal loss causes cognitive dysfunction in Alzheimer’s disease (AD). Adult hippocampal neurogenesis (AHN) is reduced in AD patients. Exercise stimulates AHN in rodents and improves memory and slows cognitive decline in AD patients. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::095993934aeeeb20b151da9a27c5acbf
https://doi.org/10.1101/2023.04.17.537272
https://doi.org/10.1101/2023.04.17.537272
Autor:
Rory A. Fisher, Mark E. Anderson, Robert M. Weiss, Adele Stewart, Zhan Gao, Jie Huang, Biswanath Maity, Jianqi Yang
PDF file - 251K, Figure S1. RGS6 is an essential mediator of Dox-induced increases in p53 in mouse atrium. Figure S2. Quantification of key apoptotic signaling proteins in ventricles of mice treated with Dox. Figure S3. Induction of RGS6 by Dox is tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bda37ce81e26134f7fb7f6576fd7a155
https://doi.org/10.1158/0008-5472.22399514.v1
https://doi.org/10.1158/0008-5472.22399514.v1
Doxorubicin (DXR), among the most widely used cancer chemotherapy agents, promotes cancer cell death via activation of ataxia telangiectasia mutated (ATM) and the resultant upregulation of tumor suppressor p53. The exact mechanism by which DXR activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe5fae54b21090f91d43addf7afc639
https://doi.org/10.1158/0008-5472.c.6502754.v1
https://doi.org/10.1158/0008-5472.c.6502754.v1
Autor:
Rory A. Fisher, Mark E. Anderson, Robert M. Weiss, Adele Stewart, Zhan Gao, Jie Huang, Biswanath Maity, Jianqi Yang
PDF file - 34K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::231dedbe9c3c4405349b778d32dd9c08
https://doi.org/10.1158/0008-5472.22399511.v1
https://doi.org/10.1158/0008-5472.22399511.v1
Autor:
Bandana Chakravarti, Jianqi Yang, Katelin E. Ahlers‐Dannen, Zili Luo, Heather A. Flaherty, David K. Meyerholz, Mark E. Anderson, Rory A. Fisher
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 11 (2017)
BackgroundCongenital heart defects are the most common birth defects worldwide. Although defective Notch signaling is the major cause of mouse embryonic death from cardiovascular defects, how Notch signaling is regulated during embryonic vasculogenes
Externí odkaz:
https://doaj.org/article/bbe0f47063ba4ad8b10c5236d1b87293
Autor:
Jianqi Yang, Alison N DeVore, Daniel A Fu, Mackenzie M Spicer, Mengcheng Guo, Samantha G Thompson, Katelin E Ahlers-Dannen, Federica Polato, Andre Nussenzweig, Rory A Fisher
Publikováno v:
Life Science Alliance. 6:e202201729
Precise determination of transgene zygosity is essential for use of transgenic mice in research. Because integration loci of transgenes are usually unknown due to their random insertion, assessment of transgene zygosity remains a challenge. Current z