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pro vyhledávání: '"Root Tracy S"'
Autor:
Jane McLeod, David C. James, Leon P. Pybus, Andrew J. Racher, Stephen J. Wilkinson, Root Tracy S, Peter M. O'Callaghan
Publikováno v:
Biotechnology and Bioengineering. 108:2193-2204
In this study we have combined empirically derived mathematical models of intracellular Mab synthesis to quantitatively compare the degree to which individual cellular processes limit recombinant IgG(4) monoclonal antibody production by GS-CHO cells
Autor:
Andrew J. Racher, Elaine Martin, Christopher J. O’Malley, Gary Montague, Richard M. Alldread, Root Tracy S, Lang Dietmar, Jane F. Povey, Carol M. Trim, Marc Feary, Christopher Mark Smales
Publikováno v:
Journal of biotechnology. 184
Despite many advances in the generation of high producing recombinant mammalian cell lines over the last few decades, cell line selection and development is often slowed by the inability to predict a cell line's phenotypic characteristics (e.g. growt