Výsledky vyhledávání - "Roosa E, Kallionpää"

Akademický článek

Neurotrophic tyrosine receptor kinase gene fusions in adult and pediatric patients with solid tumors: a clinicogenomic biobank and record linkage study of expression frequency and patient characteristics from Finland

Autor: Wei Zhang, Arndt A. Schmitz, Roosa E. Kallionpää, Merja Perälä, Niina Pitkänen, Mikko Tukiainen, Erika Alanne, Korinna Jöhrens, Renate Schulze-Rath, Bahman Farahmand, Jihong Zong

Publikováno v: Acta Oncologica, Vol 63, Iss 1 (2024)

Background: Neurotrophic tyrosine receptor kinase (NTRK) gene fusions are oncogenic drivers. Using the Auria Biobank in Finland, we aimed to identify and characterize patients with these gene fusions, and describe their clinical and tumor characteris

Externí odkaz: https://doaj.org/article/e095f9124f444d38a0377cda8832f56f

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Akademický článek

Increased incidence of melanoma in children and adolescents in Finland in 1990–2014: nationwide re-evaluation of histopathological characteristics

Autor: Emma K. Rousi, Roope A. Kallionpää, Roosa E. Kallionpää, Susanna M. Juteau, Lauri A. I. Talve, Micaela M. Hernberg, Pia P. Vihinen, Veli-Matti Kähäri, Ilkka O. Koskivuo

Publikováno v: Annals of Medicine, Vol 54, Iss 1, Pp 244-252 (2022)

Background Changes in the incidence of melanoma in children and adolescents have been reported in Europe and in the USA in the recent decades. Aims The aim of this study was to examine the incidence of paediatric and adolescent melanomas in Finland i

Externí odkaz: https://doaj.org/article/a40c86903f8d40769a966df1c6d68722

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Akademický článek

An assessment of prevalence of Type 1 CFI rare variants in European AMD, and why lack of broader genetic data hinders development of new treatments and healthcare access.

Autor: Amy V Jones, Darin Curtiss, Claire Harris, Tom Southerington, Marco Hautalahti, Pauli Wihuri, Johanna Mäkelä, Roosa E Kallionpää, Enni Makkonen, Theresa Knopp, Arto Mannermaa, Erna Mäkinen, Anne-Mari Moilanen, Tongalp H Tezel, SCOPE Study group, Nadia K Waheed

Publikováno v: PLoS ONE, Vol 17, Iss 9, p e0272260 (2022)

PurposeAdvanced age-related macular degeneration (AAMD) risk is associated with rare complement Factor I (FI) genetic variants associated with low FI protein levels (termed 'Type 1'), but it is unclear how variant prevalences differ between AMD patie

Externí odkaz: https://doaj.org/article/102db8fb14d347068d79affca482c0d2

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Subjective experiences during dexmedetomidine- or propofol-induced unresponsiveness and non-rapid eye movement sleep in healthy male subjects

Autor: Katja Valli, Linda Radek, Roosa E. Kallionpää, Annalotta Scheinin, Jaakko Långsjö, Kaike Kaisti, Oskari Kantonen, Jarno Korhonen, Tero Vahlberg, Antti Revonsuo, Harry Scheinin

Background: Anaesthetic-induced unresponsiveness and non-rapid eye movement (NREM) sleep share common neural pathways and neurophysiological features. We hypothesised that these states bear resemblance also at the experiential level. Methods: We comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c3e3869a19780373f51a86fc0046ea
http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-22701

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Decreased Thalamic Activity Is a Correlate for Disconnectedness During Anesthesia with Propofol, Dexmedetomidine and Sevoflurane but not S-Ketamine

Autor: Oskari Kantonen, Lauri Laaksonen, Michael Alkire, Annalotta Scheinin, Jaakko Långsjö, Roosa E Kallionpää, Kaike Kaisti, Linda Radek, Jarkko Johansson, Timo Laitio, Anu Maksimow, Joonas Scheinin, Mikko Nyman, Mika Scheinin, Olof Solin, Tero Vahlberg, Antti Revonsuo, Katja Valli, Harry Scheinin

Publikováno v: The Journal of Neuroscience. :JN-RM

Establishing the neural mechanisms responsible for the altered global states of consciousness during anesthesia and dissociating these from other drug-related effects remains a challenge in consciousness research. We investigated differences in brain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4f1a3a3638e21c06f62d38b019896aa8
https://doi.org/10.1523/jneurosci.2339-22.2023

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Abstract 925: NTRK gene fusion in adults and pediatrics with solid tumors: a record linkage study of expression frequency and patient characteristics using the Auria Biobank in Finland

Autor: Wei Zhang, Merja Perälä, Roosa E. Kallionpää, Niina Pitkänen, Korinna Jöhrens, Renate Schulze-Rath, Arndt A Schmitz, Helen Guo, Jihong Zong

Publikováno v: Cancer Research. 83:925-925

Introduction: Selective tropomyosin receptor kinase (TRK) inhibitors are targeted therapies for patients with solid tumors harboring a neurotrophic-receptor tyrosine kinase (NTRK) gene fusion. Estimates of the frequency of NTRK gene fusions and knowl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b134c3d008047c9981f012666f4593e1
https://doi.org/10.1158/1538-7445.am2023-925

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On no man's land: Subjective experiences during unresponsive and responsive sedative states induced by four different anesthetic agents

Autor: Harry Scheinin, Antti Revonsuo, Annalotta Scheinin, Roosa E. Kallionpää, Lauri T Laaksonen, Anu Maksimow, Ville Rajala, Nils Sandman, Lauri Koskinen, Timo Laitio, Linda Radek, Katja Valli

Publikováno v: Consciousness and cognition. 96

To understand how anesthetics with different molecular mechanisms affect consciousness, we explored subjective experiences recalled after responsive and unresponsive sedation induced with equisedative doses of dexmedetomidine, propofol, sevoflurane,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fced9773f99728304f2308635cdf7267
https://pubmed.ncbi.nlm.nih.gov/34801782

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