Ageing of Plasmodium falciparum malaria sporozoites alters their motility, infectivity and reduces immune activation in vitro

Autor: Roos van Schuijlenburg, Samaneh Azargoshasb, Clarize M. de Korne, Jeroen C. Sijtsma, Sascha Bezemer, Alwin J. van der Ham, Els Baalbergen, Fiona Geurten, Laura M. de Bes-Roeleveld, Severine C. Chevalley-Maurel, Matthias N. van Oosterom, Fijs W. B. van Leeuwen, Blandine Franke-Fayard, Meta Roestenberg

Publikováno v: Malaria Journal, Vol 23, Iss 1, Pp 1-14 (2024)

Abstract Background Sporozoites (SPZ), the infective form of Plasmodium falciparum malaria, can be inoculated into the human host skin by Anopheline mosquitoes. These SPZ migrate at approximately 1 µm/s to find a blood vessel and travel to the liver

Externí odkaz: https://doaj.org/article/2581459e4177448180bc03a9a2272c08

Latent CMV Infection Is Associated With Lower Influenza Virus-Specific Memory T-Cell Frequencies, but Not With an Impaired T-Cell Response to Acute Influenza Virus Infection

Autor: Sara P. H. van den Berg, Josien Lanfermeijer, Ronald H. J. Jacobi, Marion Hendriks, Martijn Vos, Roos van Schuijlenburg, Nening M. Nanlohy, José A. M. Borghans, Josine van Beek, Debbie van Baarle, Jelle de Wit

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

Latent infection with cytomegalovirus (CMV) is assumed to contribute to the age-associated decline of the immune system. CMV induces large changes in the T-cell pool and may thereby affect other immune responses. CMV is expected to impact especially

Externí odkaz: https://doaj.org/article/48600be757ac4c13aa1cc289914a90e5

Plasmodium sporozoites induce regulatory macrophages.

Autor: Béatrice M F Winkel, Leonard R Pelgrom, Roos van Schuijlenburg, Els Baalbergen, Munisha S Ganesh, Heleen Gerritsma, Clarize M de Korne, Nikolas Duszenko, Marijke C C Langenberg, Séverine C Chevalley-Maurel, Hermelijn H Smits, Esther C de Jong, Bart Everts, Blandine Franke-Fayard, Meta Roestenberg

Publikováno v: PLoS Pathogens, Vol 16, Iss 9, p e1008799 (2020)

Professional antigen-presenting cells (APCs), like macrophages (Mϕs) and dendritic cells (DCs), are central players in the induction of natural and vaccine-induced immunity to malaria, yet very little is known about the interaction of SPZ with human

Externí odkaz: https://doaj.org/article/58c91a03f912407e8e352d2ee4e768ef

Generation of a genetically modified chimeric plasmodium falciparum parasite expressing plasmodium vivax circumsporozoite protein for malaria vaccine development

Autor: Takashi Imai, Rianne van der Laak, Fiona J. A. Geurten, Surendra Kumar Kolli, Miguel Prudêncio, Yukiko Miyazaki, Chris J. Janse, Brandon K. Wilder, Shahid M. Khan, Catherin Marin-Mogollon, Jai Ramesar, Shinya Miyazaki, Hans Kroeze, Koen J. Dechering, Arturo Reyes-Sandoval, Angelika Sturm, Roos van Schuijlenburg, Ahmed M. Salman, Blandine Franke-Fayard, António M. Mendes, Severine Chevalley-Maurel

Publikováno v: Frontiers in Cellular and Infection Microbiology, 10. FRONTIERS MEDIA SA
Frontiers in Cellular and Infection Microbiology
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)

Copyright © 2020 Miyazaki, Marin-Mogollon, Imai, Mendes, van der Laak, Sturm, Geurten, Miyazaki, Chevalley-Maurel, Ramesar, Kolli, Kroeze, van Schuijlenburg, Salman, Wilder, Reyes-Sandoval, Dechering, Prudencio, Janse, Khan and ̂ Franke-Fayard. Thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::160e8875c9bbd50967a63732bacc3167
https://www.frontiersin.org/articles/10.3389/fcimb.2020.591046/full

A supramolecular platform technology for bacterial cell surface modification

Autor: Meta Roestenberg, Mick M. Welling, Fijs W. B. van Leeuwen, Clarize M. de Korne, Nikolas Duszenko, Roos van Schuijlenburg, Beatrice M. F. Winkel, Danny M. van Willigen

Publikováno v: ACS Infectious Diseases, 6(7), 1734-1744. AMER CHEMICAL SOC
ACS Infectious Diseases

In an era of antimicrobial resistance, a better understanding of the interaction between bacteria and the sentinel immune system is needed to discover new therapeutic targets for combating bacterial infectious disease. Sentinel immune cells such as m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74080121b68dc785574c4f68f67c2ff4
https://hdl.handle.net/1887/3184365