Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Roos H Mars-Groenendijk"'
Autor:
Armand Paauw, Holger C Scholz, Roos H Mars-Groenendijk, Lennard J M Dekker, Theo M Luider, Hans C van Leeuwen
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 1, p e0011006 (2023)
BackgroundBurkholderia mallei and Burkholderia pseudomallei are both potential biological threat agents. Melioidosis caused by B. pseudomallei is endemic in Southeast Asia and Northern Australia, while glanders caused by B. mallei infections are rare
Externí odkaz:
https://doaj.org/article/178b5c2ae2ef44629050dae49534dffa
Autor:
E. Spalburg, A.J. de Neeling, Gijsbert M. Grotenbreg, Daan Noort, Roos H. Mars-Groenendijk, Hermen S. Overkleeft, Annemiek D. Knijnenburg, Mark Overhand, G. A. Van Der Marel
Publikováno v:
Helvetica Chimica Acta. 95:2544-2561
This article presents a series of ring-extended gramicidin S derivatives, 9-14, that have four ornithine residues as polar protonated side chains and one modified turn region containing a mono-functionalized cis-δ-oxetane, δ-furanoid, or δ-pyranoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b532d020ae0c08c196ef2165a7433920
https://doi.org/10.1002/hlca.201200497
https://doi.org/10.1002/hlca.201200497
Autor:
Daan Noort, M.J. van Raaij, Annemiek D. Knijnenburg, A.J. de Neeling, Roos H. Mars-Groenendijk, Emile Spalburg, José M. Otero, Herman S. Overkleeft, Antonio L. Llamas-Saiz, P. Keizer, Varsha V. Kapoerchan, Mark Overhand, G. A. Van Der Marel
Publikováno v:
Bioorganic & Medicinal Chemistry. 20:6059-6062
A series of gramicidin S derivatives 4-15 are presented that have four ornithine residues as polar protonated side chains and two central hydrophobic amino acids with unaltered turn regions. These peptides were screened against human erthrocytes and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8c2c965e08ca04008f2834daa32239d
https://doi.org/10.1016/j.bmc.2012.08.038
https://doi.org/10.1016/j.bmc.2012.08.038
Autor:
Annemiek D. Knijnenburg, Mark Overhand, Daan Noort, Gijs A. van der Marel, Roos H. Mars-Groenendijk, Herman S. Overkleeft, Adriaan W. Tuin, José M. Otero, Antonio L. Llamas-Saiz, Albert J. de Neeling, Emile Spalburg, Mark J. van Raaij
Publikováno v:
Chemistry - A European Journal. 17:3995-4004
Monobenzylated sugar amino acids (SAAs) that differ in ether ring size (containing an oxetane, furanoid, and pyranoid ring) were synthesized and incorporated in one of the β-turn regions of the cyclo-decapeptide gramicidin S (GS). CD, NMR spectrosco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db1ab9defd3a674de0c4c92adc5eed1c
https://doi.org/10.1002/chem.201002895
https://doi.org/10.1002/chem.201002895
Autor:
Roos H. Mars-Groenendijk, Varsha V. Kapoerchan, Annemiek D. Knijnenburg, Mark Overhand, Daan Noort, Herman S. Overkleeft, Gijs A. van der Marel, Emile Spalburg, Albert J. de Neeling
Publikováno v:
Bioorganic & Medicinal Chemistry. 18:8403-8409
Ring extended Gramicidin S analogues containing adamantane amino acids and six cationic residues were designed and evaluated. Systematic replacement of the hydrophobic residues with adamantane amino acids resulted in a small set of compounds with var
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9720f732ec0cc00c1659eca008664a9b
https://doi.org/10.1016/j.bmc.2010.09.018
https://doi.org/10.1016/j.bmc.2010.09.018
Autor:
Floris J. Bikker, Roos H. Mars-Groenendijk, Helma Dijk-Knijnenburg, Edwin J.A. Veldhuizen, Linda C.L. Boele, Albert van Dijk, Wendy Esmeralda Kaman-Van Zanten, Henk P. Haagsman, E. Margo Molhoek
Publikováno v:
Molhoek, E M, van Dijk, A, Veldhuizen, E J A, Dijk-Knijnenburg, H, Mars-Groenendijk, R H, Boele, L C L, Kaman, W E, Haagsman, H P & Bikker, F J 2010, ' Chicken cathelicidin-2-derived peptides with enhanced immunomodulatory and antibacterial activities against biological warfare agents ', International Journal of Antimicrobial Agents, vol. 36, no. 3, pp. 271-274 . https://doi.org/10.1016/j.ijantimicag.2010.06.001
International Journal of Antimicrobial Agents
International Journal of Antimicrobial Agents, Elsevier, 2010, 36 (3), pp.271. ⟨10.1016/j.ijantimicag.2010.06.001⟩
International Journal of Antimicrobial Agents, 36(3), 271-274. Elsevier
International Journal of Antimicrobial Agents, 3, 36, 271-274
International Journal of Antimicrobial Agents
International Journal of Antimicrobial Agents, Elsevier, 2010, 36 (3), pp.271. ⟨10.1016/j.ijantimicag.2010.06.001⟩
International Journal of Antimicrobial Agents, 36(3), 271-274. Elsevier
International Journal of Antimicrobial Agents, 3, 36, 271-274
Host defence peptides (HDPs) are considered to be excellent candidates for the development of novel therapeutic agents. Recently, it was demonstrated that the peptide C1-15, an N-terminal segment of chicken HDP cathelicidin-2, exhibits potent antibac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f902ec9f4996614b3f22e2fecde55423
https://doi.org/10.1016/j.ijantimicag.2010.06.001
https://doi.org/10.1016/j.ijantimicag.2010.06.001
Autor:
Herman S. Overkleeft, Daan Noort, Gijsbert M. Grotenbreg, Albert J. de Neeling, Emile Spalburg, Gijsbert A. van der Marel, Mark Overhand, Annemiek D. Knijnenburg, Roos H. Mars-Groenendijk
Publikováno v:
ChemMedChem. 4:1976-1979
(Chemical Equation Presented) A series of ring-extended gramicidin S (GS) derivatives containing furanoid sugar amino acids were evaluated. Although the extended GS derivatives have a less well-defined secondary structure as determined by NMR and CD,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d33c7f22703e59550c9b245426d09837
https://doi.org/10.1002/cmdc.200900379
https://doi.org/10.1002/cmdc.200900379
Autor:
Mark Overhand, Emile Spalburg, Roos H. Mars-Groenendijk, Gijsbert M. Grotenbreg, Adriaan W. Tuin, Daan Noort, Albert J. de Neeling, Herman S. Overkleeft, Gijsbert A. van der Marel
Publikováno v:
Bioorganic & Medicinal Chemistry. 17:6233-6240
Loloatin C is a cyclic cationic antimicrobial peptide which is active against Gram positive as well as certain Gram negative bacteria. Unfortunately, it is equally potent against human erythrocytes. To probe the structure-activity relationship of thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c97411ef41386ab9890ebb09c2f07a7
https://doi.org/10.1016/j.bmc.2009.07.049
https://doi.org/10.1016/j.bmc.2009.07.049
Autor:
Gijsbert A. van der Marel, Herman S. Overkleeft, Gijsbert M. Grotenbreg, Daan Noort, Roos H. Mars-Groenendijk, Albert J. de Neeling, Emile Spalburg, Mark Overhand, Dimitrios Konstantinos Palachanis, Adriaan W. Tuin, Annelies Buizert
Publikováno v:
European Journal of Organic Chemistry. 2009:4231-4241
The synthesis of three new analogues of the cyclic cationic antimicrobial peptide Gramicidin S is described. These derivatives contain a modified turn region in which the DPhe-Pro motif has been replaced by a constrained furanoid sugar amino acid or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1560e470fe57e5c491d1dedc382c3084
https://doi.org/10.1002/ejoc.200900460
https://doi.org/10.1002/ejoc.200900460
Autor:
Eefje Engels, Daan Noort, Gijsbert A. van der Marel, José M. Otero, Mark J. van Raaij, Henk J. Busscher, Roos H. Mars-Groenendijk, Mark Overhand, Herman S. Overkleeft, Antonio L. Llamas-Saiz, Matthijs van der Knaap
Publikováno v:
Bioorganic & Medicinal Chemistry, 17(17), 6318-6328. PERGAMON-ELSEVIER SCIENCE LTD
The synthesis of new analogues of the cationic antimicrobial peptide gramicidin S, having a modified D-phenylalanine residue, their antibacterial properties against several Gram positive and negative strains, as well as their hemolytic activity is re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::decd45525d1fe99ce1e3c2371484b0c7
https://doi.org/10.1016/j.bmc.2009.07.042
https://doi.org/10.1016/j.bmc.2009.07.042