Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Roopesh Krishnankutty"'
Autor:
Ilham Bettahi, Roopesh Krishnankutty, Morana Jaganjac, Noor Nabeel M. Suleiman, Manjunath Ramanjaneya, Jayakumar Jerobin, Shaimaa Hassoun, Meis Alkasem, Ibrahem Abdelhakam, Ahmad Iskandarani, Tareq A. Samra, Vidya Mohamed-Ali, Abdul Badi Abou-Samra
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2023)
BackgroundSkeletal muscle is the main site for insulin-dependent glucose disposal. The hyperinsulinemic euglycemic clamp (HIEC) is the gold standard for the assessment of insulin sensitivity (IS). We have previously shown that insulin sensitivity, me
Externí odkaz:
https://doaj.org/article/27b577be02a74089bd1c19eb0c59c7ac
Autor:
Marin Kuntic, Ivana Kuntic, Roopesh Krishnankutty, Adrian Gericke, Matthias Oelze, Tristan Junglas, Maria Teresa Bayo Jimenez, Paul Stamm, Margaret Nandudu, Omar Hahad, Karin Keppeler, Steffen Daub, Ksenija Vujacic-Mirski, Sanela Rajlic, Lea Strohm, Henning Ubbens, Qi Tang, Subao Jiang, Yue Ruan, Kenneth G. Macleod, Sebastian Steven, Thomas Berkemeier, Ulrich Pöschl, Jos Lelieveld, Hartmut Kleinert, Alex von Kriegsheim, Andreas Daiber, Thomas Münzel
Publikováno v:
Redox Biology, Vol 59, Iss , Pp 102580- (2023)
Worldwide, up to 8.8 million excess deaths/year have been attributed to air pollution, mainly due to the exposure to fine particulate matter (PM). Traffic-related noise is an additional contributor to global mortality and morbidity. Both health risk
Externí odkaz:
https://doaj.org/article/a3483da95ed34c90ad76ad47abd956f7
Autor:
Afsheen Raza, Abdul Q. Khan, Varghese Philipose Inchakalody, Sarra Mestiri, Zeenath Safira K. M. Yoosuf, Takwa Bedhiafi, Dina Moustafa Abo El-Ella, Nassiba Taib, Shereena Hydrose, Shayista Akbar, Queenie Fernandes, Lobna Al-Zaidan, Roopesh Krishnankutty, Maysaloun Merhi, Shahab Uddin, Said Dermime
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-16 (2022)
Abstract Colorectal cancer (CRC) is one of the most common cancers worldwide. The diagnosis, prognosis and therapeutic monitoring of CRC depends largely on tissue biopsy. However, due to tumor heterogeneity and limitations such as invasiveness, high
Externí odkaz:
https://doaj.org/article/5e82a513701045539425d72e1a459430
Autor:
Sara Al-Khawaga, MD, Roopesh Krishnankutty, PhD, Gulab Sher, PhD, Khairunnisa Hussain, MD, Joerg Buddenkotte, MD, PhD, Martin Steinhoff, MD, PhD
Publikováno v:
JAAD Case Reports, Vol 16, Iss , Pp 164-167 (2021)
Externí odkaz:
https://doaj.org/article/8208fc23ad1c440a977f7708da15ab0b
Autor:
Afsheen Raza, Maysaloun Merhi, Varghese Philipose Inchakalody, Roopesh Krishnankutty, Allan Relecom, Shahab Uddin, Said Dermime
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-11 (2020)
Abstract Introduction Cancer Immunotherapy has recently emerged as a promising and effective modality to treat different malignancies. Antigenic profiling of cancer tissues and determination of any pre-existing immune responses to cancer antigens may
Externí odkaz:
https://doaj.org/article/ed6d6e68f7fe4ff1b38b008b2b33167f
Autor:
Lubna Therachiyil, Roopesh Krishnankutty, Fareed Ahmad, Jericha M. Mateo, Shahab Uddin, Hesham M. Korashy
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6395 (2022)
Ovarian cancer (OC) ranks first in cancer-related deaths out of all female reproductive malignancies with high-pitched tumor relapse and chemoresistance. Several reports correlate cancer occurrences with exposure to xenobiotics via induction of a pro
Externí odkaz:
https://doaj.org/article/aef8b6997fc943be997d94d148b6ab72
Autor:
Lubna Therachiyil, Javeria Haroon, Fairooz Sahir, Kodappully S. Siveen, Shahab Uddin, Michal Kulinski, Joerg Buddenkotte, Martin Steinhoff, Roopesh Krishnankutty
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Colorectal cancer (CRC) forms one of the highest ranked cancer types in the world with its increasing incidence and mortality rates despite the advancement in cancer therapeutics. About 50% of human CRCs are reported to have defective p53 expression
Externí odkaz:
https://doaj.org/article/f9aa8d93b5794f61a66ae67e4d7f647b
Autor:
Ajaz A. Bhat, Najeeb Syed, Lubna Therachiyil, Sabah Nisar, Sheema Hashem, Muzafar A. Macha, Santosh K. Yadav, Roopesh Krishnankutty, Shanmugakonar Muralitharan, Hamda Al-Naemi, Puneet Bagga, Ravinder Reddy, Punita Dhawan, Anthony Akobeng, Shahab Uddin, Michael P. Frenneaux, Wael El-Rifai, Mohammad Haris
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 2, p 569 (2020)
Claudins, a group of membrane proteins involved in the formation of tight junctions, are mainly found in endothelial or epithelial cells. These proteins have attracted much attention in recent years and have been implicated and studied in a multitude
Externí odkaz:
https://doaj.org/article/49ea36261947487d8c6a133ffca9e798
Autor:
Maysaloun Merhi, Afsheen Raza, Varghese Philipose Inchakalody, Abdulqadir Jeprel Japer Nashwan, Niloofar Allahverdi, Roopesh Krishnankutty, Shahab Uddin, Abdul Rehman Zar Gul, Mohammed Ussama Al Homsi, Said Dermime
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Targeting the programmed cell death protein-1 (PD-1)/PD-1 ligand (PD-L1) pathway has been shown to enhance T cell-mediated antitumor immunity. Clinical responses are limited to subgroups of patients. The search for biomarkers of response is a strateg
Externí odkaz:
https://doaj.org/article/83ef72a25e804ec4bbd4b3c89444ff3c
Autor:
Kirti S Prabhu, Kodappully S Siveen, Shilpa Kuttikrishnan, Ahmad Iskandarani, Magdalini Tsakou, Iman W Achkar, Lubna Therachiyil, Roopesh Krishnankutty, Aijaz Parray, Michal Kulinski, Maysaloun Merhi, Said Dermime, Ramzi M Mohammad, Shahab Uddin
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180895 (2017)
The X-linked inhibitor of apoptosis (XIAP) is a viable molecular target for anticancer drugs that overcome apoptosis-resistance of malignant cells. XIAP is an inhibitor of apoptosis, mediating through its association with BIR3 domain of caspase 9. Em
Externí odkaz:
https://doaj.org/article/c429cea1ae88482caf73d07a2ad77fbd