Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Roopa Ramamoorthi"'
Autor:
Wilian A. Cortopassi, Emma Gunderson, Yasmin Annunciato, Antony.E.S. Silva, Amália dos Santos Ferreira, Carolina Bioni Garcia Teles, Andre S. Pimentel, Roopa Ramamoorthi, Marcos L Gazarini, Mario R. Meneghetti, Rafael.V.C. Guido, Dhelio B. Pereira, Matthew P. Jacobson, Antoniana U. Krettli, Anna Caroline C Aguiar
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 20, Iss , Pp 121-128 (2022)
Malaria is among the tropical diseases that cause the most deaths in Africa. Around 500,000 malaria deaths are reported yearly among African children under the age of five. Chloroquine (CQ) is a low-cost antimalarial used worldwide for the treatment
Externí odkaz:
https://doaj.org/article/0b9cbb46649a4e53a7ef050c9041a6cc
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 4, Iss 3, Pp 220-225 (2014)
Neglected tropical diseases (NTDs), malaria, and tuberculosis have a devastating effect on an estimated 1.6 billion people worldwide. The World Intellectual Property Organization (WIPO) Re:Search consortium accelerates the development of new drugs, v
Externí odkaz:
https://doaj.org/article/c4c2870a64c7469f996f90b2cabc50c4
Autor:
Kliment A. Verba, Jin Liu, Zheng Wang, Robert A. Drakas, Marc Adler, Dominique C. Mitchell, Aidan Keith, Richard T. Beresis, Luo Ding, Sarah Lively, Y. Christina Hwang, Tsz Kin M. Tsui, Tingting Qing, Changliang He, LeeAnn L. Wang, John D. Gordan, Vijay Ramani, Roopa Ramamoorthi
Publikováno v:
Cancer Research. 80:5228-5228
Cancer treatment has been considerably advanced by the relatively recent development of small molecules capable of inhibiting oncogenic kinase signaling, but exogenous enhancement of tumor suppressive signaling remains elusive. Here, we sought to des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11bf87beca4859d410465b0eddf85178
https://doi.org/10.1158/1538-7445.am2020-5228
https://doi.org/10.1158/1538-7445.am2020-5228
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 4, Iss 3, Pp 220-225 (2014)
International Journal for Parasitology: Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance
Graphical abstract
Highlights • WIPO Re:Search leverages pharmaceutical assets to advance anthelmintic research. • BIO Ventures for Global Health (BVGH) facilitates collaborations and capacity building. • Novartis scientists trained a Came
Highlights • WIPO Re:Search leverages pharmaceutical assets to advance anthelmintic research. • BIO Ventures for Global Health (BVGH) facilitates collaborations and capacity building. • Novartis scientists trained a Came
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05f4ca4bbf4b488b3cb8709753951ed9
http://www.sciencedirect.com/science/article/pii/S2211320714000256
http://www.sciencedirect.com/science/article/pii/S2211320714000256
Publikováno v:
Future medicinal chemistry. 7(6)
Schistosomiasis, one of 17 diseases deemed to be neglected by the World Health Organization, has received little attention from the biopharmaceutical industry. Due to this, only a handful of drugs have been developed to treat schistosomiasis, with on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18fe9beb7c2bf72ec841b1ee570cfa12
https://pubmed.ncbi.nlm.nih.gov/25996066
https://pubmed.ncbi.nlm.nih.gov/25996066
Publikováno v:
Chemical reviews. 114(22)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92bed12b1375932db4c7afbe64b56158
https://pubmed.ncbi.nlm.nih.gov/25229276
https://pubmed.ncbi.nlm.nih.gov/25229276
Autor:
Roopa Ramamoorthi, W. A. Pine, Anthony J. Sinskey, Gregory Stephanopoulos, Mattheos A. G. Koffas
Publikováno v:
Applied Microbiology and Biotechnology. 50:346-352
Pyruvate carboxylase is an important anaplerotic enzyme replenishing oxaloacetate consumed for biosynthesis during growth, or lysine and glutamic acid production in industrial fermentations. We used regions of homology from pyruvate carboxylase seque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2db37ea54ef0d2a6edb0e8b73ea85ea8
https://doi.org/10.1007/s002530051302
https://doi.org/10.1007/s002530051302
Autor:
Jennifer Dent, Lisa Marie Nelson, Katy M. Graef, Johannes Christian Wichard, Roopa Ramamoorthi
Publikováno v:
Pharmaceutical patent analyst. 2(5)
1BIO Ventures for Global Health, Seattle, WA, USA 2WIPO, Geneva, Switzerland *Author for correspondence: Tel.: +1 206 732 2131 E-mail: jdent@bvgh.org Advances in science, medicine and technology have enabled high-income countries to dramatically redu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b237c1040f1d5f2d968eaebebf1f4e
https://pubmed.ncbi.nlm.nih.gov/24237166
https://pubmed.ncbi.nlm.nih.gov/24237166
Autor:
David A. Brenner, Stefan Zahn, Claudia Hirth-Dietrich, Myung-Sam Cho, Paul Ng, Roopa Ramamoorthi, Greg Roldan, Clark Pan, Andreas Knorr, Baisong Mei, Nikki Feirt, Blair U. Bradford, Peggy Lum, Barbara Krebs, Adrian Tomkinson, Bodo Brocks, Ellen Cheung, Sabine Kraft, Michael Schauer, Christopher J. Parsons
Publikováno v:
Hepatology (Baltimore, Md.). 40(5)
Liver fibrosis is characterized by increased synthesis, and decreased degradation, of extracellular matrix (ECM) within the injured tissue. Decreased ECM degradation results, in part, from increased expression of tissue inhibitor of metalloproteinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::204e19c058cfdae82581260583d1316f
https://pubmed.ncbi.nlm.nih.gov/15389776
https://pubmed.ncbi.nlm.nih.gov/15389776
Methylobacterium extorquens AM1 pqqEF are genes required for synthesis of pyrroloquinoline quinone (PQQ). The nucleotide sequence of these genes indicates PqqE belongs to an endopeptidase family, including PqqF of Klebsiella pneumoniae, and M. extorq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::623b17bb7c385091a66037064494e24d
https://resolver.caltech.edu/CaltechAUTHORS:SPRIjbact96
https://resolver.caltech.edu/CaltechAUTHORS:SPRIjbact96
