Výsledky vyhledávání

In vitro inhibition of matrix metalloproteinases, invasion and growth of Fanconi anemia human FANCA and FANCC lymphoblasts by nutrient mixture

Autor: Roomi, M.W., Bhanap, B., Roomi, N.W., Niedzwiecki, A., Rath, M.

Aim: Fanconi anemia is a rare genetic disorder with high propensity for development of cancers, such as aplastic anemia, leukemia and head and neck cancers. Collagen digesting matrix metalloproteinase (MMP) enzymes have been implicated in for their r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1456::421f43f9533f9f45795b33ea608a6527
http://dspace.nbuv.gov.ua/handle/123456789/145369

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Repression of matrix metalloproteinases and inhibition of cell invasion by a nutrient mixture, containing ascorbic acid, lysine, proline, and green tea extract on human fanconi anemia fibroblast cell lines

Autor: Roomi, M.W., Roomi, N.W., Bhanap, B., Niedzwiecki, A., Rath, M.

Aim: Fanconi Anemia, an autosomal recessive disorder, is characterized by chromosomal abnormality leading to birth defects, progressive bone marrow failure, and a high probability of developing malignancy at an early age. Head and neck squamous cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1456::5744f6474d55777d29577b2e4d33d2ef
http://dspace.nbuv.gov.ua/handle/123456789/139121

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Inhibition of growth and expression of inflammation mediators in human leukemic cell line U-937 by a nutrient mixture

Autor: Roomi, M.W., Kalinovsky, T., Roomi, N.W., Rath, M., Niedzwiecki, A.

Aim - a nutrient mixture (NM) containing ascorbic acid, lysine, proline and green tea extract has exhibited anticancer activity in vitro and in vivo in a number of cancer cell lines. We investigated the effect of NM on human leukemic myeloid U-937 ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::43dd54719845efecd2f798c1b31c72b2
http://dspace.nbuv.gov.ua/handle/123456789/145227

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Nutrient mixture inhibits in vitro and in vivo growth of human acute promyelocytic leukemia HL-60 cells

Autor: Roomi, M.W., Roomi, N.W., Bhanap, B., Rath, M., Niedzwiecki, A.

Aim: Untreated acute promyelocytic leukemia is the most malignant form of acute leukemias, with median survival of less than one month. We investigated in vitro and in vivo synergistic effects of a nutrient mixture (NM) containing ascorbic acid, lysi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1456::2589bfedf8fe1997d90a84dda372e9e6
http://dspace.nbuv.gov.ua/handle/123456789/138674

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In vivo and in vitro antitumor effects of nutrient mixture in murine leukemia cell line P-388

Autor: Roomi, M.W., Roomi, N.W., Bhanap, B., Rath, M., Niedzwiecki, A.

Aim: Leukemia is characterized by uncontrolled marrow cell proliferation and metastatic foci. We investigated the antitumor potential of a nutrient mixture on malignant leukemia P-388 cells. Methods: The nutrient mixture containing lysine, proline, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1456::5e351d54ce8c6dc583d244a7a7d7a2a4
http://dspace.nbuv.gov.ua/handle/123456789/138629

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Ascorbate depletion increases growth and metastasis of melanoma cells in vitamin C deficient mice

Autor: Cha, J., Roomi, M.W., Ivanov, V., Kalinovsky, T., Niedzwiecki, A., Rath, M.

Aim: Our main objective was to determine the effect of ascorbate supplementation in mice unable to synthesize ascorbic acid (gulo KO) when challenged with murine B16FO cancer cells. Methods: Gulo KO female mice 36–40 weeks of age were deprived of o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1456::2a0afd72e90e3142bcdba329abba4a5b
http://dspace.nbuv.gov.ua/handle/123456789/138671

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Inhibition of invasion and MMPs by a nutrient mixture in human cancer cell lines: a correlation study

Autor: Roomi, M.W., Monterrey, J.C., Kalinovsky, T., Rath, M., Niedzwiecki, A.

The aim of this paper is to examine the correlation between in vitro MMP-2 and MMP-9 secretion and Matrigel invasion in 42 different human cancer cell lines (selected on the basis of organ malignancies) treated with a nutrient mixture (NM).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1456::c151bc3464e3b70ea043b7750b3f8ffc
http://dspace.nbuv.gov.ua/handle/123456789/32303

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Antiangiogenic properties of a nutrient mixture in a model of hemangioma

Autor: Roomi, M.W., Kalinovsky, T., Niedzwiecki, A., Rath, M.

The pathogenesis of hemangiomas is still largely unknown and the current therapy, such as systemic corticosteroid, vincristine, and interferon-alpha, is toxic and remains unsatisfactory. A nutrient mixture (NM) containing lysine, proline, ascorbic ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1456::bdad43d599fbfff1ffa4e572219dddee
http://dspace.nbuv.gov.ua/handle/123456789/138207

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Antineoplastic effects of nutrient mixture on Raji and Jurkat t cells: the two highly aggressive non hodgkin’s lymphoma cell lines

Autor: Roomi, M.W., Bhanap, B.A., Roomi, N.W., Rath, M., Niedzwiecki, A.

Non-Hodgkin lymphomas incidence has increased more than 70% in last 25 years. Aggressiveness, higher relapse rate, and treatment complications pose significant barriers. Decreased food intake and side effects of treatments make cancer patients vulner

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1456::0ac74fb87ece1059ba065948233a5077
http://dspace.nbuv.gov.ua/handle/123456789/134402

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