Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Roodolph S. Pierre"'
Autor:
Yiji Liao, Chen-Hao Chen, Tengfei Xiao, Bárbara de la Peña Avalos, Eloise V. Dray, Changmeng Cai, Shuai Gao, Neel Shah, Zhao Zhang, Avery Feit, Pengya Xue, Zhijie Liu, Mei Yang, Ji Hoon Lee, Han Xu, Wei Li, Shenglin Mei, Roodolph S. Pierre, Shaokun Shu, Teng Fei, Melissa Duarte, Jin Zhao, James E. Bradner, Kornelia Polyak, Philip W. Kantoff, Henry Long, Steven P. Balk, X. Shirley Liu, Myles Brown, Kexin Xu
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance We identified a group of DNA repair genes directly induced by EZH2 and repressed by EZH2 inhibitors. Expression of these genes predicts the response of wild-type EZH2-harboring solid tumors to EZH2 inhibitors. Most importantly, our findi
Autor:
Avery S. Feit, Teng Fei, X. Shirley Liu, Yiji Liao, Tengfei Xiao, Roodolph S. Pierre, Wei Li, Changmeng Cai, Pengya Xue, Melissa Duarte, Neel Shah, Jin Zhao, Philip W. Kantoff, Steven P. Balk, James Elliot Bradner, Han Xu, Henry W. Long, Chen-Hao Chen, Shaokun Shu, Shenglin Mei, Shuai Gao, Kexin Xu, Ji Hoon Lee, Zhijie Liu, Myles Brown, Kornelia Polyak, Mei Yang
SummaryDrugs that block the activity of the methyltransferase EZH2 are in clinical development for the treatment of non-Hodgkin lymphomas harboring gain-of-function EZH2 mutations that enhance its polycomb repressive function. In contrast, in castrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df40426e2c20bcfa188a435653183a96
https://doi.org/10.1101/2020.09.11.291534
https://doi.org/10.1101/2020.09.11.291534