Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ronny Falk"'
Autor:
Fadi Rofo, Jos Buijs, Ronny Falk, Ken Honek, Lars Lannfelt, Anna M. Lilja, Nicole G. Metzendorf, Tobias Gustavsson, Dag Sehlin, Linda Söderberg, Greta Hultqvist
Publikováno v:
Translational Neurodegeneration, Vol 10, Iss 1, Pp 1-16 (2021)
Abstract Background Amyloid-β (Aβ) immunotherapy is a promising therapeutic strategy in the fight against Alzheimer’s disease (AD). A number of monoclonal antibodies have entered clinical trials for AD. Some of them have failed due to the lack of
Externí odkaz:
https://doaj.org/article/e3112d378ac74be8899dc991771ba21a
Autor:
Linda Söderberg, Dag Sehlin, Jos Buijs, Nicole G. Metzendorf, Tobias Gustavsson, Ronny Falk, Fadi Rofo, Greta Hultqvist, Anna M. Lilja, Lars Lannfelt, Ken Honek
Publikováno v:
Translational Neurodegeneration, Vol 10, Iss 1, Pp 1-16 (2021)
Translational Neurodegeneration
Translational Neurodegeneration
Background Amyloid-β (Aβ) immunotherapy is a promising therapeutic strategy in the fight against Alzheimer’s disease (AD). A number of monoclonal antibodies have entered clinical trials for AD. Some of them have failed due to the lack of efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::359582bca4f3b37df6cd3645595fee07
https://doaj.org/article/e3112d378ac74be8899dc991771ba21a
https://doaj.org/article/e3112d378ac74be8899dc991771ba21a
Autor:
Jahan Salma, Matti Lam, Mohsen Moslem, Ronny Falk, Niklas Dahl, B-M Anderlid, Robin Pronk, Sara B. Linker, Anna Falk, Mansoureh Shahsavani, Jens Schuster, Kelly Day, Fred H. Gage
Publikováno v:
Molecular Psychiatry. 23:1674-1684
Lissencephaly comprises a spectrum of brain malformations due to impaired neuronal migration in the developing cerebral cortex. Classical lissencephaly is characterized by smooth cerebral surface and cortical thickening that result in seizures, sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb2b45dd34ace28e9e12b6efe84b4185
https://doi.org/10.1038/mp.2017.175
https://doi.org/10.1038/mp.2017.175
Autor:
Anna-Karin, Haylock, Johan, Nilvebrant, Anja, Mortensen, Irina, Velikyan, Marika, Nestor, Ronny, Falk
Publikováno v:
Oncotarget
Aim The aim of this study was to generate and characterize scFv antibodies directed to human CD44v6, as well as to radiolabel and evaluate top candidates in vitro and in vivo for their potential use in CD44v6-targeted molecular imaging in cancer pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ae6d5c94c38fe05481584da680b1a4e
https://pubmed.ncbi.nlm.nih.gov/29029420
https://pubmed.ncbi.nlm.nih.gov/29029420
Autor:
Liana Fasching, Marie E. Jönsson, Malin Parmar, Per Ludvik Brattås, Ronny Falk, Patric Jern, Jenny Nelander Wahlestedt, Anna Falk, Mansoureh Shahsavani, Johan Jakobsson
Publikováno v:
Cell reports. 18(1)
Endogenous retroviruses (ERVs), which make up 8% of the human genome, have been proposed to participate in the control of gene regulatory networks. In this study, we find a region- and developmental stage-specific expression pattern of ERVs in the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e33be457a286992b7f306c519bd82c2
https://pubmed.ncbi.nlm.nih.gov/28052240
https://pubmed.ncbi.nlm.nih.gov/28052240
Publikováno v:
FEMS Microbiology Letters. 215:139-147
An effort is presented to create expression vectors which would allow expression of an inserted gene fragment in three reading frames in a single vector from a single promoter but with three separate ribosome binding sites (RBS). Each expression fram
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da696738c3fda2224100b84ef970072
https://doi.org/10.1111/j.1574-6968.2002.tb11383.x
https://doi.org/10.1111/j.1574-6968.2002.tb11383.x
Autor:
Mathias Uhlén, Cecilia Eriksson, Sophia Hober, Margareta Ramström, Henrik Wernérus, Ronny Falk
Publikováno v:
Biotechnology journal. 6(1)
One commonly used strategy to gain information on the proteins in a cell is to isolate the proteins of interest by specific binders, often antibodies. Not only the specificity of the capturing antibodies but also the washing and elution conditions ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bdb8ec10c4c1ba89d4ce808c78f1136
https://pubmed.ncbi.nlm.nih.gov/21170982
https://pubmed.ncbi.nlm.nih.gov/21170982
Publikováno v:
Biomolecular engineering. 24(2)
With the completion of the human genome project (HUGO) during recent years, gene function, protein abundance and expression patterns in tissues and cell types have emerged as central areas for the scientific community. A mapped human proteome will ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca6bdcd2e9b402e0e5591bfb43aa66a8
https://pubmed.ncbi.nlm.nih.gov/17376740
https://pubmed.ncbi.nlm.nih.gov/17376740
Autor:
Mats Lindskog, Marcus Runeson, Dijana Cerjan, Jenny Ödling, Ronny Falk, Jinghong Wan, Kenneth Wester, Marianne Hansson, Joakim Westberg, Anna Asplund, Cristina Al-Khalili Szigyarto, Charlotta Agaton, Jenny Ottosson, Karin Larsson, Joakim Lundeberg, Lan Lan Xu, Johanna Steen, Mattias Forsberg, Åsa Sivertsson, Caroline Asplund, Henrik Wernérus, Sophia Hober, Jan Lund, Emma Öster, Wald Lodewyckx, Harry Brumer, IngMarie Olsson, Ulla Wrethagen, Erik Malm, Linn Fagerberg, Cecilia Eriksson, Johan Rockberg, Mathias Uhlén, Erik Björling, Asif Halimi, Annelie Waldén, Rebecca Rimini, Fredrik Pontén, Jenny Fall, Hanna Tegel, Caroline Kampf, Görel Hercules, My Hedhammar, Anna Sköllermo, Mårten Sundberg, Kristina Bergström, Peter Nilsson, Linda Paavilainen, Anja Persson, Eva Wahlund, Per Oksvold, Inga Hallin, Sara Strömberg, Elisabet Andersen, Pia Angelidou, Carl Hamsten, Maria Stenvall, Bahram Amini, Kristina Magnusson, Kristoffer Gumbel, Lisa Berglund, Marica Ekström, Samuel Tourle, Adila El-Obeid, Marcus Gry Björklund, Fredrik Sterky, Ann-Catrin Andersson
Publikováno v:
Karolinska Institutet
Antibody-based proteomics provides a powerful approach for the functional study of the human proteome involving the systematic generation of protein-specific affinity reagents. We used this strategy to construct a comprehensive, antibody-based protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5274a53a20ccc4078356d16adeb0872f
https://pubmed.ncbi.nlm.nih.gov/16127175
https://pubmed.ncbi.nlm.nih.gov/16127175
Autor:
Ingmarie Höidén Guthenberg, Lovisa Göstring, Mathias Uhlén, Charlotta Agaton, Sophia Hober, Ronny Falk
Publikováno v:
Journal of chromatography. A. 1043(1)
A high stringency protocol, suitable for systematic purification of polyclonal antibodies, is described. The procedure is designed to allow the generation of target protein-specific antibodies suitable for functional annotation of proteins. Antibodie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6b549a174f708a9e45a5a7451372167
https://pubmed.ncbi.nlm.nih.gov/15317410
https://pubmed.ncbi.nlm.nih.gov/15317410