Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Ronny, Martin"'
Autor:
Hesham Elsaman, Evgeny Golubtsov, Sean Brazil, Natanya Ng, Isabel Klugherz, Ronny Martin, Karl Dichtl, Christoph Müller, Johannes Wagener
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Azole antifungals inhibit the sterol C14-demethylase (CYP51/Erg11) of the ergosterol biosynthesis pathway. Here we show that the azole-induced synthesis of fungicidal cell wall carbohydrate patches in the pathogenic mold Aspergillus fumigatu
Externí odkaz:
https://doaj.org/article/c262d3c2fb6c430b9997fc04d609248a
Autor:
Benedikt Schrenker, Anna Zimmermann, Thorsten Koch, Grit Walther, Ronny Martin, Daniel Kampik, Oliver Kurzai, Johanna Theuersbacher
Publikováno v:
International Journal of Medical Microbiology, Vol 314, Iss , Pp 151602- (2024)
Purpose: Fusarium keratitis is a severe infection of the anterior eye, frequently leading to keratoplasty or surgical removal of the affected eye. A major risk factor for infection is the use of contact lenses. Inadequate hygiene precautions and mold
Externí odkaz:
https://doaj.org/article/4ceb52f3444e4916b1e424728ef9a415
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 608-614 (2022)
The human body is a dynamic ecosystem consisting of millions of microbes which are often comprised under the term microbiome. Compared to bacteria, which count for the overwhelming majority of the microbiome, the number of human-associated fungi is s
Externí odkaz:
https://doaj.org/article/caed53bb827646fe9a7a907318360908
Autor:
Christine Dunker, Melanie Polke, Bianca Schulze-Richter, Katja Schubert, Sven Rudolphi, A. Elisabeth Gressler, Tony Pawlik, Juan P. Prada Salcedo, M. Joanna Niemiec, Silvia Slesiona-Künzel, Marc Swidergall, Ronny Martin, Thomas Dandekar, Ilse D. Jacobsen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
The ability of the fungal pathogen Candida albicans to undergo yeast-to-hypha transition is believed to be a key virulence factor. Here, Dunker et al. show that a filament-deficient strain is attenuated in a mouse model of intraperitoneal infection,
Externí odkaz:
https://doaj.org/article/56c898d46b974e6fb75c3234ffc538fb
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Azole resistance of the fungal pathogen Aspergillus fumigatus is an emerging problem. To identify novel mechanisms that could mediate azole resistance in A. fumigatus, we analyzed the transcriptome of a mitochondrial fission/fusion mutant that exhibi
Externí odkaz:
https://doaj.org/article/cdb6488f55154a7ba1a4bccd52c5b250
Autor:
Sophia Ruben, Enrico Garbe, Selene Mogavero, Daniela Albrecht-Eckardt, Daniela Hellwig, Antje Häder, Thomas Krüger, Katrin Gerth, Ilse D. Jacobsen, Osama Elshafee, Sascha Brunke, Kerstin Hünniger, Olaf Kniemeyer, Axel A. Brakhage, Joachim Morschhäuser, Bernhard Hube, Slavena Vylkova, Oliver Kurzai, Ronny Martin
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT The capacity of Candida albicans to reversibly change its morphology between yeast and filamentous stages is crucial for its virulence. Formation of hyphae correlates with the upregulation of genes ALS3 and ECE1, which are involved in pathog
Externí odkaz:
https://doaj.org/article/92ada380a5544ab2b0f537336c459272
Autor:
Nancy A. Chow, José F. Muñoz, Lalitha Gade, Elizabeth L. Berkow, Xiao Li, Rory M. Welsh, Kaitlin Forsberg, Shawn R. Lockhart, Rodney Adam, Alexandre Alanio, Ana Alastruey-Izquierdo, Sahar Althawadi, Ana Belén Araúz, Ronen Ben-Ami, Amrita Bharat, Belinda Calvo, Marie Desnos-Ollivier, Patricia Escandón, Dianne Gardam, Revathi Gunturu, Christopher H. Heath, Oliver Kurzai, Ronny Martin, Anastasia P. Litvintseva, Christina A. Cuomo
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Candida auris has emerged globally as a multidrug-resistant yeast that can spread via nosocomial transmission. An initial phylogenetic study of isolates from Japan, India, Pakistan, South Africa, and Venezuela revealed four populations (clad
Externí odkaz:
https://doaj.org/article/d0e6412b3a924a919ec4a337fa135384
Autor:
Axel Hamprecht, Amelia E. Barber, Sibylle C. Mellinghoff, Philipp Thelen, Grit Walther, Yanying Yu, Priya Neurgaonkar, Thomas Dandekar, Oliver A. Cornely, Ronny Martin, Oliver Kurzai
Publikováno v:
Emerging Infectious Diseases, Vol 25, Iss 9, Pp 1763-1765 (2019)
The emerging yeast Candida auris has disseminated worldwide. We report on 7 cases identified in Germany during 2015–2017. In 6 of these cases, C. auris was isolated from patients previously hospitalized abroad. Whole-genome sequencing and epidemiol
Externí odkaz:
https://doaj.org/article/bb6072804d0e409fab9bb26b0a90b0a4
Autor:
Alexander M. Aldejohann, Ronny Martin, Jane Hecht, Sebastian Haller, Volker Rickerts, Grit Walther, Tim Eckmanns, Oliver Kurzai
Publikováno v:
Deutsches Ärzteblatt international.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57054a074cf5f3883cf05de561a771c2
https://doi.org/10.3238/arztebl.m2023.0047
https://doi.org/10.3238/arztebl.m2023.0047
Autor:
Enrico Garbe, Nadja Thielemann, Sina Hohner, Animesh Kumar, Slavena Vylkova, Oliver Kurzai, Ronny Martin
Publikováno v:
Microbiology Spectrum. 11
In recent years it was shown that secretion of the toxic peptide candidalysin from hyphae of the major human fungal pathogen Candida albicans contributes heavily to its virulence. The peptide is derived from a precursor protein which is encoded by th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60fb1eb02c821d3a87e43b033c38c07d
https://doi.org/10.1128/spectrum.00253-23
https://doi.org/10.1128/spectrum.00253-23